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Pomalidomide 4'-alkylC5-acid

Pomalidomide 4'-alkylC5-acid Structure
Pomalidomide 4'-alkylC5-acid structure
CAS No.
2225940-49-6
Chemical Name:
Pomalidomide 4'-alkylC5-acid
Synonyms
Poma-C5-COOH;-alkylC5-acid;Pomalidomide-linker 3;Thalidomide-NH-C5-COOH;Thalidomide-4-NH-C5-COOH;Pomalidomide 4'-alkylC5-acid;Pomalidomide 4'-alkylC5-acid;6-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]hexanoic acid;6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexanoic acid;6-[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]hexanoic acid
CBNumber:
CB84902874
Molecular Formula:
C19H21N3O6
Molecular Weight:
387.39
MDL Number:
MFCD32063492
MOL File:
2225940-49-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:33:20
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Pomalidomide 4'-alkylC5-acid Properties

Boiling point 712.2±60.0 °C(Predicted)
Density 1.443±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 4.75±0.10(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Pomalidomide 4'-alkylC5-acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-44886 Pomalidomide-C5-acid 2225940-49-6 50MG $130 2026-05-24 Buy
BroadPharm bp-44886 Pomalidomide-C5-acid 2225940-49-6 100MG $230 2026-05-24 Buy
BroadPharm bp-44886 Pomalidomide-C5-acid 2225940-49-6 250MG $430 2026-05-24 Buy
BroadPharm bp-44886 Pomalidomide-C5-acid 2225940-49-6 500MG $750 2026-05-24 Buy
Matrix Scientific 294320 6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexanoic acid 2225940-49-6 50.00mg $100 2026-05-19 Buy
Product number Packaging Price Buy
bp-44886 50MG $130 Buy
bp-44886 100MG $230 Buy
bp-44886 250MG $430 Buy
bp-44886 500MG $750 Buy
294320 50.00mg $100 Buy

Pomalidomide 4'-alkylC5-acid Chemical Properties, Uses, Production

Description

Pomalidomide-C5-acid is an E3 ligase ligand-linker conjugate.

Uses

Pomalidomide 4'-alkylC5-acid (Example 3) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC5-acid can be used in the synthesis of PROTAC[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. Patent WO2018106870A1.

Pomalidomide 4'-alkylC5-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide 4'-alkylC5-acid Suppliers

Global Suppliers ( 48)
Supplier Tel Email Country ProdList Advantage
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
SHANGHAI FDC-CHEMICAL CO.,LTD 021-61469567 13774476675 sales@fdc-chemical.com China 10000 58
Shandong utilizing biological technology co., LTD 18669728830 15966937598 3407650895@qq.com China 5166 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Supplier Advantage
Beijing Ouhe Technology Co., Ltd 60
Daicel Chiral Technologies (China)CO.,LTD 65
Bide Pharmatech Ltd. 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Rechem science Co., Ltd. 58
Shanghai Chaolan Chemical Technology Center 58
Aikon International Limited 58
SHANGHAI FDC-CHEMICAL CO.,LTD 58
Shandong utilizing biological technology co., LTD 58
Shanghai Hongye Biotechnology Co. Ltd 58

Pomalidomide 4'-alkylC5-acid Spectrum

6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid(2225940-49-6)1HNMR

2225940-49-6 (Pomalidomide 4'-alkylC5-acid) Related Search:

E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3 Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[(4-Aminobutyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
β-Alanine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- 4-((4-azidobutyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-C5-NH2 hydrochloride

1of4

6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid Pomalidomide-linker 3 -alkylC5-acid 6-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexanoic acid Thalidomide-NH-C5-COOH 6-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]hexanoic acid Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Thalidomide-4-NH-C5-COOH Poma-C5-COOH Pomalidomide 4'-alkylC5-acid 6-[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]hexanoic acid Pomalidomide 4'-alkylC5-acid 2225940-49-6