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Pomalidomide-NH-PEG3-azide

Pomalidomide-NH-PEG3-azide Structure
Pomalidomide-NH-PEG3-azide structure
CAS No.
2271036-46-3
Chemical Name:
Pomalidomide-NH-PEG3-azide
Synonyms
IUN-36463;Pomalidomide-NH-PEG3-azide;Pomalidomide 4'-PEG3-azide;4-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;4-((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;4-[[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-
CBNumber:
CB18363902
Molecular Formula:
C21H26N6O7
Molecular Weight:
474.47
MDL Number:
MFCD32903293
MOL File:
2271036-46-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:53:00
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Pomalidomide-NH-PEG3-azide Properties

form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
HS Code  2933998090

Pomalidomide-NH-PEG3-azide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0110045 Pomalidomide 4'-PEG3-azide ≥96% 2271036-46-3 50mg $69 2026-06-04 Buy
ChemScene CS-0110045 Pomalidomide 4'-PEG3-azide ≥96% 2271036-46-3 100mg $117 2026-06-04 Buy
ChemScene CS-0110045 Pomalidomide 4'-PEG3-azide ≥96% 2271036-46-3 250mg $220 2026-06-04 Buy
ChemScene CS-0110045 Pomalidomide 4'-PEG3-azide ≥96% 2271036-46-3 500mg $439 2026-06-04 Buy
ChemScene CS-0110045 Pomalidomide 4'-PEG3-azide ≥96% 2271036-46-3 1g $592 2026-06-04 Buy
Product number Packaging Price Buy
CS-0110045 50mg $69 Buy
CS-0110045 100mg $117 Buy
CS-0110045 250mg $220 Buy
CS-0110045 500mg $439 Buy
CS-0110045 1g $592 Buy

Pomalidomide-NH-PEG3-azide Chemical Properties, Uses, Production

Uses

Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1degrader based on Rucaparib by using the PROTAC approach[1]. Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Cereblon

storage

Store at -20°C

References

[1] Shuai Wang, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. DOI:10.1038/s41589-019-0379-2

Pomalidomide-NH-PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-NH-PEG3-azide Suppliers

Global Suppliers ( 32)
Supplier Tel Email Country ProdList Advantage
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
SHANGHAI FDC-CHEMICAL CO.,LTD 021-61469567 13774476675 sales@fdc-chemical.com China 10000 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 025-86755008 17751752005 hszhang@bestfluorodrug.com China 2357 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 7201 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Supplier Advantage
Shanghai Rechem science Co., Ltd. 58
SHANGHAI FDC-CHEMICAL CO.,LTD 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Zhengzhou convergence chemical co., LTD 58
Hubei Kele Fine Chemical Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Bide Pharmatech Ltd. 58

View Latest Price from Pomalidomide-NH-PEG3-azide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-NH-PEG3-azide pictures 2025-06-07 Pomalidomide-NH-PEG3-azide
2271036-46-3
 100mg >98.00% 100mg Xian confluore Biological Technology Co., Ltd.

Pomalidomide-NH-PEG3-azide Spectrum

Pomalidomide-NH-PEG3-azide(2271036-46-3)1HNMR

2271036-46-3 (Pomalidomide-NH-PEG3-azide) Related Search:

Pomalidomide-NH-PEG2-azide Pomalidomide-NH-PEG6-azide Pomalidomide-PEG4-azide Pomalidomide-NH-PEG1-azide Pomalidomide-NH-PEG5-azide
1H-Isoindole-1,3(2H)-dione, 4-[(3-azidopropyl)amino]-2-(2,6-dioxo-3-piperidinyl)- Propanoic acid, 3-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]-, 2,2,2-trifluoroacetate (1:1) 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- 4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Poma-NH-C4-N3
4-((6-azidohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Propanoic acid, 3-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]-, 2,2,2-trifluoroacetate (1:1) Pomalidomide-PEG2-CO2H Pomalidomide-PEG4-CO2H Propanoic acid, 3-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]-, 2,2,2-trifluoroacetate (1:1)
4-((5-azidopentyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG3-CO2H 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-(2-hydroxyethoxy)ethyl]amino]-

1of4

Pomalidomide-NH-PEG3-azide IUN-36463 4-((2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide 4'-PEG3-azide 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)- 4-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione 4-[[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 2271036-46-3