1H-PYRAZOL-4-YLAMINE
- CAS No.
- 28466-26-4
- Chemical Name:
- 1H-PYRAZOL-4-YLAMINE
- Synonyms
- 1H-Pyrazol-4-amine;4-AMINOPYRAZOLE;4-AMINO-1H-PYRAZOLE;AKOS PAO-0001;H-PYRAZOL-4-YLAMINE;1H-Pyrazole-4-amine;4-Aminopyrazole 95%;1H-PYRAZOL-4-YLAMINE;1H-Pyrazol-4-amine (9CI, ACI)
- CBNumber:
- CB1840324
- Molecular Formula:
- C3H5N3
- Molecular Weight:
- 83.09
- MDL Number:
- MFCD01693729
- MOL File:
- 28466-26-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Aminopyrazole 95% | 700940 | 1g | $130 |
| 1H-Pyrazol-4-amine >98.0%(GC)(T) | P2523 | 1g | $77 |
| 4-Amino-1H-pyrazole | A628905 | 1g | $120 |
| 4-Amino-1H-pyrazole | A628905 | 5g | $250 |
| 4-Amino-1H-pyrazole | FA55418 | 10g | $350 |
| More product size | |||
| Melting point | 75-77°C |
|---|---|
| Boiling point | 142.17°C (rough estimate) |
| Density | 1.0248 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| form | powder to crystal |
| pka | 17.70±0.50(Predicted) |
| color | White to Brown to Dark purple |
| Sensitive | Hygroscopic |
| InChI | InChI=1S/C3H5N3/c4-3-1-5-6-2-3/h1-2H,4H2,(H,5,6) |
| InChIKey | AXINVSXSGNSVLV-UHFFFAOYSA-N |
| SMILES | N1C=C(N)C=N1 |
| CAS DataBase Reference | 28466-26-4 |
| NIST Chemistry Reference | 4-NH2-pyrazole(28466-26-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UQ4993000 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933199090 | |||||||||
| NFPA 704 |
|
1H-PYRAZOL-4-YLAMINE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 700940 | 4-Aminopyrazole 95% | 28466-26-4 | 1g | $130 | 2025-07-31 | Buy |
| TCI Chemical | P2523 | 1H-Pyrazol-4-amine >98.0%(GC)(T) | 28466-26-4 | 1g | $77 | 2025-07-31 | Buy |
| TRC | A628905 | 4-Amino-1H-pyrazole | 28466-26-4 | 1g | $120 | 2021-12-16 | Buy |
| TRC | A628905 | 4-Amino-1H-pyrazole | 28466-26-4 | 5g | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA55418 | 4-Amino-1H-pyrazole | 28466-26-4 | 10g | $350 | 2021-12-16 | Buy |
1H-PYRAZOL-4-YLAMINE Chemical Properties,Uses,Production
Form
powder
Uses
4-Aminopyrazole, is a versatile building block for the preparation of pharmaceutical and biologically active compounds. 4-Amino-1H-pyrazole, has also shown to have anticonvulsant activity, and thus can be used in the treatment of epileptic seizures.
Synthesis
2075-46-9
28466-26-4
4-Nitropyrazole (1.13 g, 10 mmol) was dissolved in methanol (10 mL) under hydrogen (1 atm) atmosphere and 10% Pd-C catalyst (0.1 g) was added. The reaction mixture was stirred at 25 °C for 12 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 4-aminopyrazole (860 mg, yield: 100%), which could be used in subsequent reactions without further purification.
References
[1] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0252; 0253
[2] ChemMedChem, 2016, p. 1695 - 1699
[3] Patent: CN105418616, 2016, A. Location in patent: Paragraph 0118; 0119
[4] Organic and Biomolecular Chemistry, 2013, vol. 11, # 3, p. 395 - 399
[5] Patent: WO2017/178510, 2017, A1. Location in patent: Page/Page column 297
1H-PYRAZOL-4-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | lee@unipharm-sd.com | China | 1202 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12071 | 58 |
View Lastest Price from 1H-PYRAZOL-4-YLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 1H-PYRAZOL-4-YLAMINE
28466-26-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2019-07-06 | 1H-PYRAZOL-4-YLAMINE
28466-26-4
|
US $1.00 / kg | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- 1H-PYRAZOL-4-YLAMINE
28466-26-4
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1H-PYRAZOL-4-YLAMINE
28466-26-4
- US $1.00 / kg
- 98%
- Career Henan Chemical Co
