Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
![Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Structure](CAS/20211123/GIF/444287-85-8.gif)
- CAS No.
- 444287-85-8
- Chemical Name:
- Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
- Synonyms
- TNF-α-IN-8;2-Azido-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl]acetamide;2-Azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide;Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
- CBNumber:
- CB210780264
- Molecular Formula:
- C15H12N6O5
- Molecular Weight:
- 356.3
- MDL Number:
- MOL File:
- 444287-85-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0643616 | TNF-α-IN-8 95.0% | 444287-85-8 | 5mg | $108 | 2026-06-04 | Buy |
| ChemScene | CS-0643616 | TNF-α-IN-8 95.0% | 444287-85-8 | 10mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0643616 | TNF-α-IN-8 95.0% | 444287-85-8 | 25mg | $350 | 2026-06-04 | Buy |
| ChemScene | CS-0643616 | TNF-α-IN-8 95.0% | 444287-85-8 | 50mg | $561 | 2026-06-04 | Buy |
| ChemScene | CS-0643616 | TNF-α-IN-8 95.0% | 444287-85-8 | 100mg | $899 | 2026-06-04 | Buy |
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Chemical Properties, Uses, Production
Uses
TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases[1]. TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References
[1] Robarge MJ, et al. ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF. WO/2002/059106. 2002.
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Becas pharmatech Ltd. | +86-13912903754 13912903754 | info@becaspharma.com | China | 3963 | 58 |
| Wuhan Brin Technology Co., Ltd. | 3456065315 13260619011 | 3456065315@qq.com | China | 2464 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38904 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Wuhan Huahan Dingcheng New Material Technology Co., Ltd | 18963961905 | huahandingcheng@sina.com | China | 484 | 58 |
| Nanjing XinRui ChemTech Co.,Ltd | 19850079587 | 3752448275@qq.com | China | 1792 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from Acetamide, 2-azido-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-19 | TNF-α-IN-8
444287-85-8
|
$2270.00 | 10g | TargetMol Chemicals Inc. |
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- TNF-α-IN-8
444287-85-8
- $2270.00
- TargetMol Chemicals Inc.
