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(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid structure

CAS No.: 80544-17-8

Chemical Name:: (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid

Synonyms: NICA;MICAAcid;Cefixime Impurity 9;Mannitol Impurity 65;Cefixime Impurity 39;Cefixime side chain acid;Cefoxime side chain acid;(Z)-(2-Aminothiazol-4-yl)-;Cefacoxime side chain acid;Cefixime side chain acid( TBKWCLS)

CBNumber:: CB2110046

Molecular Formula:: C8H9N3O5S

Molecular Weight:: 259.24

MDL Number:: MFCD07782100

MOL File:: 80544-17-8.mol

MSDS File:: SDS

Last updated:2026-05-27 23:53:07

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(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Properties

Melting point	>160°C (dec.)
Boiling point	481.1±51.0 °C(Predicted)
Density	1+-.0.1 g/cm3(Predicted)
storage temp.	Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
pka	2.40±0.10(Predicted)
form	Solid
color	White to Off-White
InChI	InChI=1S/C8H9N3O5S/c1-15-5(12)2-16-11-6(7(13)14)4-3-17-8(9)10-4/h3H,2H2,1H3,(H2,9,10)(H,13,14)/b11-6-
InChIKey	AGFYEFQBXHONNW-WDZFZDKYSA-N
SMILES	C(O)(=O)/C(/C1=CSC(N)=N1)=N\OCC(OC)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P302+P352-P304+P340-P305+P351+P338

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	V1753	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 98%(HPLC)	80544-17-8	5g	$16	2026-06-04	Buy
AK Scientific	V1753	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 98%(HPLC)	80544-17-8	25g	$21	2026-06-04	Buy
AK Scientific	V1753	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 98%(HPLC)	80544-17-8	100g	$73	2026-06-04	Buy
AK Scientific	V1753	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 98%(HPLC)	80544-17-8	500g	$327	2026-06-04	Buy
AK Scientific	J51600	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 95%	80544-17-8	5g	$12	2026-06-04	Buy

Product number	Packaging	Price	Buy
V1753	5g	$16	Buy
V1753	25g	$21	Buy
V1753	100g	$73	Buy
V1753	500g	$327	Buy
J51600	5g	$12	Buy

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Chemical Properties,Uses,Production

Uses

(Z)-2-(2-amino-4-thiazolyl)-2-methoxycarbonylmethoxyiminoacetic acid (cefixime side chain acid) is an important side chain for the synthesis of the third and fourth generation cephalosporins It is of great economic and practical value to strengthen its research and development.

Uses

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid can be used as an intermediate in organic synthesis.

Preparation

The synthesis of cefixime side chain acid takes tert-butyl acetoacetate as raw material, through the steps of oximation, etherification, chlorination, cyclization and hydrolysis, to synthesize (Z)-2-(2-amino Thiazol-4-yl)-2-methoxycarbonylmethoxyiminoacetic acid.

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Suppliers

Global( 151)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Qingdao Port Liwei Import and Export Co., Ltd	13853286203 13853286203	shy96321@163.com	China	40	58
JINAN MEIGAO BIOPHARMATECH CO. LTD	13853286203 18205419756	shy96321@163.com	China	20	58
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
shanghai science Bio-Pharmceutical.co,ltd.	021-021-57872719 13761402923	245662540@qq.com	China	299	60
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
XiaoGan ShenYuan ChemPharm co,ltd	15527621225; 15527621225	1791901229@qq.com	China	6746	52
China Langchem Inc.	0086-21-58956006		China	7798	57
Shanghai Jian Chao Chemical Technology Co., Ltd.	150-2103-5486 18017383231	983544897@qq.com	China	9336	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Qingdao Port Liwei Import and Export Co., Ltd	58
JINAN MEIGAO BIOPHARMATECH CO. LTD	58
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
shanghai science Bio-Pharmceutical.co,ltd.	60
Adamas Reagent, Ltd.	59
XiaoGan ShenYuan ChemPharm co,ltd	52
China Langchem Inc.	57
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
Bide Pharmatech Ltd.	60

View Lastest Price from (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-05-25	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 80544-17-8		1KG	99.0%+	300 MT	Shaanxi Dideu Medichem Co. Ltd
	2019-07-06	(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 80544-17-8	$7.00	1kg	99%	100kg	Career Henan Chemical Co

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid
80544-17-8
99.0%+
Shaanxi Dideu Medichem Co. Ltd

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid
80544-17-8
$7.00
99%
Career Henan Chemical Co

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Spectrum

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid(80544-17-8)¹HNMR

80544-17-8((Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid)Related Search:

Glycine Ethyl 2-(Chlorosulfonyl)acetate Ethyl acetate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Chloroacetic acid

Acetic anhydride (Z)-2-(2-Aminothiazol-4-yl)-2-(tert-butoxycarbonylmethoxyimino)acetic acid Diethyl thiophosphoryl-(Z)-2-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl)isopropoxyiminoacetate (Z)-2-(tert-Butoxycarbonylprop-2-oxyimino)-2-(2-tritylaminothiazol-4-yl)acetic acid Ethyl 2-(2-aminothiazole-4-yl)-2-(1-tert-butoxycarbonyl-1-methylethoxyimino)acetate

Cefixime (Z)-2-(tert-Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid 4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-, anhydride with diethyl hydrogen phosphate, (Z)- 4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-2-oxoethoxy]imino]-, anhydride with O,O-diethyl hydrogen phosphorothioate 4-Thiazoleacetic acid, 2-amino-alpha-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, anhydride with diethyl hydrogen phosphate, (Z)-

Poly(methyl methacrylate) isotactic (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid (Z)-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid

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NICA (Z)-2-Amino-ALPHA-[(2-methoxy-2-oxoethoxy)-imino]-4-thiazoleacetic acid MICAAcid (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-METHOXYCARBONYLMETHOXYIMINOACETIC ACID (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid (Z)-2-(2-METHOXY-2-OXOETHOXYIMINO)-2-(2-METHYLTHIAZOL-4-YL)ACETIC ACID (Z)-(2-Aminothiazol-4-yl)- (Z)-2-(2-AMinothiazol-4-yl)-2-((2-Methoxy-2-oxoethoxy)iMino)acetic acid Cefixime side chain acid Cefixime Impurity 9 (2-AMINOTHIAZOL-4-YL)-METHOXYCARBONYLMETHOXYIMINOACETIC ACID (2Z)-2-(2-amino-4-thiazolyl)-2-(2-methoxy-2-oxoethoxy)iminoacetic acid (Z)-2-(t-MethoxycarbonylMethoxyimino)-2-(2-Aminothiazol-4-yl)Acetic Acid 4-Thiazoleacetic acid, 2-amino-α-[(2-methoxy-2-oxoethoxy)imino]-, (αZ)- (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-methoxy-2-oxoethoxy)iminoacetic acid (Z)-2-(tert-Methoxycarbonyl Methoxyimino)-2-(2-Aminothiazol-... Cefoxime side chain acid Cefacoxime side chain acid Cefixime side chain acid( TBKWCLS) Mannitol Impurity 65 Cefixime Impurity 39 (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid - [M92223] 80544-17-8