ChemicalBook >> CAS DataBase List >>(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide structure

CAS No.: 135729-78-1

Chemical Name:: (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

Synonyms: Palonosetron Impurity 3;Palonosetron Impurity 27;Palonosetron Impurity 20;Palonosetron Impurity 1;Palonosetron Impurity 25;Palonosetron Intermediate;(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra;(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide;(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide;N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide

CBNumber:: CB21135547

Molecular Formula:: C18H24N2O

Molecular Weight:: 284.4

MDL Number:: MFCD27923863

MOL File:: 135729-78-1.mol

MSDS File:: SDS

Last updated:2026-05-27 23:53:30

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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Properties

Melting point	157-159oC
Boiling point	439.2±45.0 °C(Predicted)
Density	1.17
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.75±0.20(Predicted)
color	White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	465680	S-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide	135729-78-1	100mg	$418	2026-06-03	Buy
Usbiological	465680	S-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide	135729-78-1	250mg	$694	2026-06-03	Buy
Biosynth	KFA72978	(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide	135729-78-1	5mg	$900	2026-06-04	Buy
Biosynth	KFA72978	(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide	135729-78-1	50mg	$900	2026-06-04	Buy
Biosynth	KFA72978	(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide	135729-78-1	25mg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
465680	100mg	$418	Buy
465680	250mg	$694	Buy
KFA72978	5mg	$900	Buy
KFA72978	50mg	$900	Buy
KFA72978	25mg	$900	Buy

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Chemical Properties,Uses,Production

Uses

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide synthesis

Synthesis of (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide from 5,6,7,8-Tetrahydro-naphthalene-1-carbonyl chloride and (S)-quinuclidin-3-aMine

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Preparation Products And Raw materials

Raw materials

5,6,7,8-Tetrahydro-naphthalene-1-carbonyl chloride 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid (S)-quinuclidin-3-aMine Oxalyl chloride

Preparation Products

Palonosetron

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Suppliers

Global( 87)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
SynAsst Chemical.	021-60343070		China	12731	55
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Shandong Boluoda Biological Technology Co., Ltd.	0531-68651502	2310993908@qq.com	China	3157	58
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 15250997978	1511893459@qq.com	China	4777	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Zhengzhou Huiju Chemical Co., Ltd.	0371-55900031 18137872243	3927209986@qq.com	China	9997	55
Shenzhen SUNGENING Bio-Medical Co., Ltd.	0755-28967200 13631290199	wxf@sungening.com	China	9609	60
Aikon International Limited	025-58859352 19370895928	sales01@aikonchem.com	China	15078	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
SynAsst Chemical.	55
Quality Control Solutions Ltd.	56
Shandong Boluoda Biological Technology Co., Ltd.	58
Nanjing XiZe Biotechnology CO., Ltd.	55
Amadis Chemical Company Limited	58
Zhengzhou Huiju Chemical Co., Ltd.	55
Shenzhen SUNGENING Bio-Medical Co., Ltd.	60
Aikon International Limited	58

View Lastest Price from (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-21	(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1	$3.00	1KG	98%	200KG	Career Henan Chemical Co
	2020-02-01	(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide 135729-78-1	$1.00	1KG	98%	200kgs	Career Henan Chemical Co

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
135729-78-1
$3.00
98%
Career Henan Chemical Co

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
135729-78-1
$1.00
98%
Career Henan Chemical Co

135729-78-1((S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide)Related Search:

Formamide,Deionized Formamide Benzamide Chlorantraniliprole N,N-Dimethylformamide

2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline (3S)-AMinoquinuclidine-D1 Dihydrochloride (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide-d1 N,N-Diethyl-5,6,7,8-tetrahydronaphthalene-1-carboxamide 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid

Palonosetron Impurity 6 HCl Palonosetron Impurity 8 Palonosetron impurity Palonosetron Impurity 7 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

(R,S)-Palonosetron Hydrochloride PLSQ-001 TM4-qj (6R)-Hydroxy (R,S)-Palonosetron

1of4

(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Palonosetron Impurity 20 Palonosetron Impurity 27 N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide Palonosetron Impurity 25 Palonosetron Impurity 1 (S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxaMide N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl] 5,6,7,8-tetrahydronaphthalene-1-carboxamide Palonosetron Impurity 3 Palonosetron Intermediate 1-Naphthalenecarboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-5,6,7,8-tetrahydro- (S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetra 135729-78-1 Intermediate of palonosetron hcl