6-Quinolinylmethanol
- CAS No.
- 100516-88-9
- Chemical Name:
- 6-Quinolinylmethanol
- Synonyms
- quinolin-6-ylmethanol;CC 04509;ZINC01436222;6-quinolylmethanol;6-quinolinemethanol;4-cinnolinemethanol;RARECHEM AK ML 0560;6-QUINOLINYLMETHANOL;Quinoline-6-methanol;SDCCGMLS-0065932.P001
- CBNumber:
- CB2124355
- Molecular Formula:
- C10H9NO
- Molecular Weight:
- 159.18
- MDL Number:
- MFCD03789621
- MOL File:
- 100516-88-9.mol
- MSDS File:
- SDS
| Melting point | 79-80 ºC |
|---|---|
| Boiling point | 334.8±17.0 °C(Predicted) |
| Density | 1.218±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 14.02±0.10(Predicted) |
| Appearance | Light brown to yellow Solid |
| CAS DataBase Reference | 100516-88-9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H412-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P273-P501 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 6-24/25-26-36/37/39 |
| HazardClass | IRRITANT |
| HS Code | 29334900 |
6-Quinolinylmethanol price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS1166 | 6-Hydroxymethylquinoline 97% | 100516-88-9 | 1g | $55 | 2026-06-04 | Buy |
| Activate Scientific | AS1166 | 6-Hydroxymethylquinoline 97% | 100516-88-9 | 5g | $168 | 2026-06-04 | Buy |
| Activate Scientific | AS1166 | 6-Hydroxymethylquinoline 97% | 100516-88-9 | 25g | $456 | 2026-06-04 | Buy |
| Matrix Scientific | 062389 | Quinolin-6-ylmethanol | 100516-88-9 | 500.00mg | $237 | 2026-05-18 | Buy |
| ACHEMBLOCK | X180140 | 6-Quinolinylmethanol 97% | 100516-88-9 | 25G | $250 | 2026-05-27 | Buy |
6-Quinolinylmethanol Chemical Properties,Uses,Production
Chemical Properties
Light yellow or pink powder
Synthesis
38896-30-9
100516-88-9
General procedure for the synthesis of 6-hydroxymethylquinoline from methyl 6-quinolinecarboxylate: cooling of a 0.2 M solution of methyl 6-quinolinecarboxylate (0.300 g, 1.60 mmol) in THF (8 mL) and a 0.6 M solution of diisobutylaluminum hydride (DIBAL) (0.860 mL, 4.81 mmol) in THF in an acetone-dry ice bath at -78 °C ( 8mL). The DIBAL solution was transferred to the methyl ester solution via cannula and the resulting solution was stirred for 1 h at 0 °C. The reaction was quenched by the addition of methanol (8 mL) and acetic acid (1.37 mL, 24.0 mmol) at 0 °C. After stirring for 5 min, saturated sodium tartrate solution (16 mL) was added. Stirring was continued for 20 min, followed by dilution of the reaction mixture with EtOAc (50 mL) and water (10 mL). The aqueous layer was extracted with EtOAc (3 x 50 mL). The organic phases were combined and washed once with 15 mL of water. The organic layer was dried with Na2SO4, filtered and concentrated under reduced pressure. Purification by column chromatography (50-90% EtOAc/hexane) afforded 0.236 g (93%) of 6-hydroxymethylquinoline (S3a) as a pale yellow oil.1H NMR (500 MHz, CDCl3): δ 4.89 (s, 2H), 7.35 (dd, 1H, J=4.0,8.0), 7.65 (dd, 1H, J=1.5, 9.0), 7.77 (s, 1H), 8.01 (d, 1H, J=9.0), 8.08 (d, 1H, J=4.0), 8.80 (dd, 1H, J=1.5,4.0).13C-NMR (125MHz, CDCl3): δ64.8,121.5,125.0,128.3,129.0,129.4. 136.4,139.9,147.7,150.2. HRMS-FAB (m/z): calculated value for [MH]+ C10H10NO, 160.0762; measured value: 160.0766.
References
[1] Journal of the American Chemical Society, 2008, vol. 130, # 20, p. 6404 - 6410
[2] Patent: WO2009/75778, 2009, A2. Location in patent: Page/Page column 49-50
[3] Patent: WO2004/7491, 2004, A1. Location in patent: Page 55-56
[4] Patent: WO2017/40449, 2017, A1. Location in patent: Paragraph 00363
[5] Patent: WO2011/18454, 2011, A1. Location in patent: Page/Page column 56
6-Quinolinylmethanol Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Youken Biotechnology Co., Ltd. | 15107073929 | 1150046738@qq.com | China | 464 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1399 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd. | 010-81520996 13439320863 | hengpugao@126.com | China | 159 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1996 | 58 |
View Lastest Price from 6-Quinolinylmethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-15 | 6-Quinolinylmethanol
100516-88-9
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | 6-Quinolinylmethanol
100516-88-9
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | 6-Quinolinylmethanol
100516-88-9
|
$1.00 | 1kg | 98% | 100KG | Career Henan Chemical Co |
-
- 6-Quinolinylmethanol
100516-88-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-Quinolinylmethanol
100516-88-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 6-Quinolinylmethanol
100516-88-9
- $1.00
- 98%
- Career Henan Chemical Co
