N 556
- CAS No.
- 110816-78-9
- Chemical Name:
- N 556
- Synonyms
- N 556;KY-556;KY556,KY 556;5,5'-[[2-(Lysyloxy)propane-1,3-diyl]bisoxy]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl]·2hydrochloride
- CBNumber:
- CB21363858
- Molecular Formula:
- C33H36N2O12.2ClH
- Molecular Weight:
- 725.571
- MDL Number:
- MFCD06809908
- MOL File:
- 110816-78-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 225-228 °C |
|---|---|
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| color | White to off-white |
| FDA UNII | W7074H45IM |
N 556 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | KEA81678 | KY-556 | 110816-78-9 | 1mg | $925.47 | 2026-06-04 | Buy |
| Biosynth | KEA81678 | KY-556 | 110816-78-9 | 5mg | $2615.45 | 2026-06-04 | Buy |
| Biosynth | KEA81678 | KY-556 | 110816-78-9 | 10mg | $4184.8 | 2026-06-04 | Buy |
| Biosynth | KEA81678 | KY-556 | 110816-78-9 | 25mg | $7846.5 | 2026-06-04 | Buy |
| Biosynth | KEA81678 | KY-556 | 110816-78-9 | 50mg | $12554 | 2026-06-04 | Buy |
N 556 Chemical Properties,Uses,Production
Uses
KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases.
in vivo
The oral anti-allergic effect of KY-556 (N-556) is investigated. N-556 (10-100 mg/kg, p.o.) inhibits dose-dependently the 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats, and the duration of action is longer than that of intravenous Disodium cromoglycate (DSCG). N-556 (20 and 100 mg/kg once a day for 20 consecutive days, p.o.) tends to inhibit the histamine release from actively sensitized rat lung fragments. N-556 (100 mg/kg, p.o.) shows the prolongation of survival time in the rat systemic anaphylaxis. N-556 (100 mg/kg, p.o.) significantly inhibits the increased airway resistance in experimental asthma in rats[1].
References
[1] Nakamura S, et al. Effects of N-556 on experimental allergy models in rats. Arerugi. 1990 Dec;39(12):1621-8. PMID:2096808
N 556 Preparation Products And Raw materials
Raw materials
Preparation Products
N 556 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16103 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
110816-78-9(N 556)Related Search:
1of3
