(S)-3-Piperidine-3-carboxylic acid
- CAS No.
- 851956-01-9
- Chemical Name:
- (S)-3-Piperidine-3-carboxylic acid
- Synonyms
- L(+)-NIPECOTIC ACID HCL;(S)-(+)-Nipecotic acid HCl;L(+)-nipecotic acid hydrochloride;(S)-3-Piperidine-3-carboxylic acid;(3S)-3-Piperidinecarboxylic acid hydrochloride;(3S)-piperidine-3-carboxylic acid hydrochloride;(S)-3-Piperidine-3-CarboxylicAcid hydrochloride;(3S)-3-Piperidinecarboxylic acid hydrochloride salt
- CBNumber:
- CB21502811
- Molecular Formula:
- C6H11NO2.ClH
- Molecular Weight:
- 165.62
- MDL Number:
- MFCD00211281
- MOL File:
- 851956-01-9.mol
- MSDS File:
- SDS
| storage temp. | Inert atmosphere,Room Temperature |
|---|---|
| Appearance | White to off-white Solid |
| FDA UNII | 7R91429V3L |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
(S)-3-Piperidine-3-carboxylic acid price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 64552 | L(+)-NIPECOTIC ACID HCL 97% | 851956-01-9 | 5G | $34 | 2026-04-30 | Buy |
| AstaTech | 64552 | L(+)-NIPECOTIC ACID HCL 97% | 851956-01-9 | 25G | $139 | 2026-04-30 | Buy |
| AstaTech | 64552 | L(+)-NIPECOTIC ACID HCL 97% | 851956-01-9 | 100G | $499 | 2026-04-30 | Buy |
| aablocks | AA004VZH | (S)-Piperidine-3-carboxylic acid hydrochloride 98% | 851956-01-9 | 1g | $8 | 2026-05-28 | Buy |
| aablocks | AA004VZH | (S)-Piperidine-3-carboxylic acid hydrochloride 97% | 851956-01-9 | 5g | $26 | 2026-05-28 | Buy |
(S)-3-Piperidine-3-carboxylic acid Chemical Properties, Uses, Production
Synthesis
88495-54-9
851956-01-9
The general steps for the synthesis of (S)-piperidine-3-carboxylic acid hydrochloride from N-Boc-(S)-3-carboxylic acid piperidine are as follows: Step 1. Preparation of (3S)-piperidine-3-carboxylic acid hydrochloride (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid (4.0 g, 0.017 mol) was dissolved in dichloromethane (10 mL, 0.2 mol), and a 1,4-dioxane solution (30 mL) of 4.0 M hydrogen chloride was added. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the volatiles were removed by vacuum distillation to give (3S)-piperidine-3-carboxylic acid hydrochloride in quantitative yield. The crude product did not require further purification and could be used directly in subsequent steps.LCMS analysis showed m/z 166.2 (M + H)+.
References
[1] Patent: US2006/4049, 2006, A1. Location in patent: Page/Page column 49
[2] Patent: WO2012/131379, 2012, A1. Location in patent: Page/Page column 25
[3] Patent: US2014/206703, 2014, A1. Location in patent: Paragraph 0106; 0107
(S)-3-Piperidine-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-3-Piperidine-3-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| The future of Shanghai Industrial Co., Ltd. | 021-61552785 | sales@shshiji.com | China | 9531 | 55 |
| SINO High Goal Chemical Technology Co., Ltd. | 021-57646680 18306277365 | sunkai@chembiobanksh.com | China | 2039 | 55 |
| Chengdu Firster Pharmaceutical Co., Ltd. | 028-87078428 028-87074958 | chengzhenyong@cdfirster.com | China | 2580 | 60 |
| Sichuan Ampebiochem Co., Ltd. | 028-65294243 18682730901 | sales@ampebiochem.com | China | 1000 | 58 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| SanoChem (Chengdu) Tech. Co., Ltd. | 28-87999436 02887999436 | sales@sano-chem.com | China | 3792 | 55 |
| parabiochem | 025-83453382-8005 | sale@parabiochem.com | China | 9577 | 55 |
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