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2-Fluoro-4-nitrobenzonitrile

2-Fluoro-4-nitrobenzonitrile Structure
2-Fluoro-4-nitrobenzonitrile structure
CAS No.
34667-88-4
Chemical Name:
2-Fluoro-4-nitrobenzonitrile
Synonyms
2-Fluoro-4-nitrobenzonitrile;2-Fluoro-4-nitrobenzonitrile ,98%;Benzonitrile, 2- fluoro- 4- nitro-
CBNumber:
CB2166124
Molecular Formula:
C7H3FN2O2
Molecular Weight:
166.11
MDL Number:
MFCD04038715
MOL File:
34667-88-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:24
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2-Fluoro-4-nitrobenzonitrile Properties

Melting point 0°C
Boiling point 0°C
Density 1.41±0.1 g/cm3(Predicted)
Flash point 0°C
storage temp. Sealed in dry,Room Temperature
Appearance Off-white to light yellow Solid
CAS DataBase Reference 34667-88-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37/39-36
RIDADR  3439
HS Code  29269090

2-Fluoro-4-nitrobenzonitrile price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 276665 2-Fluoro-4-nitro-benzonitrile Asreported 34667-88-4 5g $345 2026-06-03 Buy
Usbiological 276665 2-Fluoro-4-nitro-benzonitrile Asreported 34667-88-4 10g $473 2026-06-03 Buy
Usbiological 276665 2-Fluoro-4-nitro-benzonitrile Asreported 34667-88-4 25g $638 2026-06-03 Buy
Usbiological 276665 2-Fluoro-4-nitro-benzonitrile Asreported 34667-88-4 50g $858 2026-06-03 Buy
Usbiological 276665 2-Fluoro-4-nitro-benzonitrile Asreported 34667-88-4 100g $1168 2026-06-03 Buy
Product number Packaging Price Buy
276665 5g $345 Buy
276665 10g $473 Buy
276665 25g $638 Buy
276665 50g $858 Buy
276665 100g $1168 Buy

2-Fluoro-4-nitrobenzonitrile Chemical Properties, Uses, Production

Chemical Properties

Light yellow solid

Synthesis

2-Fluoro-4-nitro-benzamide

350-32-3

2-FLUORO-4-NITROBENZONITRILE

34667-88-4

General procedure for the synthesis of 2-fluoro-4-nitrobenzonitrile from 2-fluoro-4-nitrobenzamide: A mixture of 2-fluoro-4-nitrobenzamide (0.83 g, 4.6 mmol) and phosphorus pentoxide/hexamethyldisiloxane in 1,2-dichloroethane (20 mL) was heated and refluxed for 4 hr at 100 °C under nitrogen atmosphere. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently filtered through a silicone plug, washed first with hexane (200 mL) and then with 5% methanol/chloroform mixture (400 mL). The methanol/chloroform washings were combined and concentrated under reduced pressure to give 2-fluoro-4-nitrobenzonitrile (0.71 g, 95% yield) as a beige solid.1H NMR (DMSO-d6) data were as follows: δ 8.46 (dd, J = 9.5, 2.0 Hz, 1H), 8.37-8.22 (m, 2H).

References

[1] Journal of Heterocyclic Chemistry, 1997, vol. 34, # 4, p. 1163 - 1172
[2] Patent: US6344459, 2002, B1. Location in patent: Page column 70-71
[3] European Journal of Medicinal Chemistry, 2018, vol. 143, p. 1325 - 1344
[4] Journal of Medicinal Chemistry, 2001, vol. 44, # 23, p. 3856 - 3871

2-Fluoro-4-nitrobenzonitrile synthesis

1427-07-2
34667-88-4
Synthesis of 2-Fluoro-4-nitrobenzonitrile from 2-Fluoro-4-nitrotoluene

2-Fluoro-4-nitrobenzonitrile Preparation Products And Raw materials

Raw materials

Ethanol Potassium carbonate Chromium(VI) oxide Triethylamine Tetrahydrofuran
Trifluoroacetic anhydride Diethyl ether Ethyl acetate Oxalyl chloride 2-Fluoro-4-nitrotoluene
Sulfuric acid 2-Fluoro-4-nitrobenzoic acid 2-Fluoro-4-nitrobenzoyl chloride 2-Fluoro-4-nitro-benzamide 2 4-Dinitrobenzonitrile 97
1-Bromo-2,4-dinitrobenzene

1of4

Preparation Products

2,4-Difluorobenzonitrile 4-Amino-2-fluorobenzonitrile

2-Fluoro-4-nitrobenzonitrile Suppliers

Global Suppliers ( 139)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Capot Chemical Co., Ltd 66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Shanghai Harvest Chemical Industrial Co., Ltd. 64
China DongFan Chemical Co.,LTD 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Tianjin Jinyuda Chemical Co., Ltd. 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55

View Latest Price from 2-Fluoro-4-nitrobenzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-FLUORO-4-NITROBENZONITRILE pictures 2019-07-12 2-FLUORO-4-NITROBENZONITRILE
34667-88-4
 $1.00 1KG 99% 100kg Career Henan Chemical Co

2-Fluoro-4-nitrobenzonitrile Spectrum

2-FLUORO-4-NITROBENZONITRILE(34667-88-4)1HNMR2-FLUORO-4-NITROBENZONITRILE(34667-88-4)19FNMR

34667-88-4 (2-Fluoro-4-nitrobenzonitrile) Related Search:

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4-Nitrobenzonitrile

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Benzonitrile, 2- fluoro- 4- nitro- 2-Fluoro-4-nitrobenzonitrile ,98% 2-Fluoro-4-nitrobenzonitrile 34667-88-4 207979-19-4 C7H3N2O2F Fluorine series