5-Pyrimidinemethanol
- CAS No.
- 25193-95-7
- Chemical Name:
- 5-Pyrimidinemethanol
- Synonyms
- PYRIMIDIN-5-YLMETHANOL;RARECHEM AK ML 0566;5-pyrimidinemethanol;Pyrimidine-5-methanol;5-Pyrimidinylmethanol;5-(HYDROXYMETHYL)PYRIMIDINE;5-(Hydroxymethyl)pyrimidi...;5-Pyrimidinemethanol (7CI,9CI);5-(Hydroxymethyl)pyrimidine 97%;(PYRIMIDIN-5-YL)METHANOL,PURITY
- CBNumber:
- CB2211431
- Molecular Formula:
- C5H6N2O
- Molecular Weight:
- 110.11
- MDL Number:
- MFCD03789623
- MOL File:
- 25193-95-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Pyrimidinemethanol | 437058 | 500mg | $382 |
| 5-Pyrimidinemethanol | 437058 | 1g | $552 |
| 5-(Hydroxymethyl)pyrimidine Asreported | 296187 | 500mg | $360 |
| 5-(Hydroxymethyl)pyrimidine Asreported | 296187 | 1g | $592 |
| 5-(Hydroxymethyl)pyrimidine Asreported | 296187 | 2g | $827 |
| More product size | |||
| Melting point | 51-52 °C |
|---|---|
| Boiling point | 250.8±15.0 °C(Predicted) |
| Density | 1.227±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 13.43±0.10(Predicted) |
| color | Yellow |
| CAS DataBase Reference | 25193-95-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302+H332-H314-H317-H412 |
| Precautionary statements | P261-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 |
| HS Code | 2933599590 |
5-Pyrimidinemethanol price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 437058 | 5-Pyrimidinemethanol | 25193-95-7 | 500mg | $382 | 2026-06-03 | Buy |
| Usbiological | 437058 | 5-Pyrimidinemethanol | 25193-95-7 | 1g | $552 | 2026-06-03 | Buy |
| Usbiological | 296187 | 5-(Hydroxymethyl)pyrimidine Asreported | 25193-95-7 | 500mg | $360 | 2026-06-03 | Buy |
| Usbiological | 296187 | 5-(Hydroxymethyl)pyrimidine Asreported | 25193-95-7 | 1g | $592 | 2026-06-03 | Buy |
| Usbiological | 296187 | 5-(Hydroxymethyl)pyrimidine Asreported | 25193-95-7 | 2g | $827 | 2026-06-03 | Buy |
5-Pyrimidinemethanol Chemical Properties,Uses,Production
Uses
5-Pyrimidinemethanol is a reagent used in the synthesis of melanin-concentrating hormone receptor 1 antagonists.Also used in the preparation of annulated 5-aryl-substituted pyridines.
Synthesis
10070-92-5
25193-95-7
Step 3. Synthesis of 5-pyrimidinemethanol. 5-Pyrimidinecarboxaldehyde (2 g, 18.50 mmol, 1.00 eq.) and sodium borohydride (2 g) were dissolved in methanol (100 mL) and the reaction was stirred for 30 min at 0-10 °C. Upon completion of the reaction, the solvent was removed by vacuum concentration and the resulting residue was purified by silica gel column chromatography with dichloromethane/methanol (50:1, v/v) as eluent to give 1.2 g (59% yield) of the target compound 5-pyrimidine methanol as a light yellow solid. Mass spectrometry result: m/z = 111.0 [M + H]+.
References
[1] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0218
[2] Patent: WO2013/19621, 2013, A1. Location in patent: Page/Page column 41
[3] Journal of Organic Chemistry, 2000, vol. 65, # 26, p. 9261 - 9264
[4] Patent: WO2009/45381, 2009, A1. Location in patent: Page/Page column 29-30
[5] Patent: WO2009/45386, 2009, A1. Location in patent: Page/Page column 32-33
5-Pyrimidinemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9040 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
View Lastest Price from 5-Pyrimidinemethanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 5-Pyrimidinemethanol
25193-95-7
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2021-07-13 | 5-Pyrimidine methanol
25193-95-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-09 | 5-Pyrimidine methanol
25193-95-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-Pyrimidinemethanol
25193-95-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-Pyrimidine methanol
25193-95-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-Pyrimidine methanol
25193-95-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
