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Pyrimidine-5-carboxaldehyde

Pyrimidine-5-carboxaldehyde structure

CAS No.: 10070-92-5

Chemical Name:: Pyrimidine-5-carboxaldehyde

Synonyms: PYRIMIDINE-5-CARBALDEHYDE;5-FORMYLPYRIMIDINE;5-PYRIMIDINECARBOXALDEHYDE;RARECHEM AK ML 0565;PyriMidin-5-carbaldehyde;5-Pyrimidinecarbaldehyde;Pyrimidine-5-formaldehyde;PYRIMIDINE-5-CARBOXALDEHYDE;PYRIMIDINE-5-CARBOXYALDEHYDE;Pyrimidine-5-carboxylaldehyde

CBNumber:: CB8412180

Molecular Formula:: C5H4N2O

Molecular Weight:: 108.1

MDL Number:: MFCD03426065

MOL File:: 10070-92-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:04:22

Product description	Number	Pack Size	Price
pyrimidine-5-carboxaldehyde Aldrich^CPR	CDS004733	100 mg	$93.2
Pyrimidine-5-carboxaldehyde Asreported	286546	1g	$383
Pyrimidine-5-carboxaldehyde Asreported	286546	2g	$535
Pyrimidine-5-carboxaldehyde Asreported	286546	5g	$735
Pyrimidine-5-carboxaldehyde Asreported	286546	10g	$1012
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Pyrimidine-5-carboxaldehyde Properties

Melting point	39-43°C
Boiling point	80-82°C 4mm
Density	1.23
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form	solid
pka	1.15±0.10(Predicted)
color	Light yellow to yellow
InChI	InChI=1S/C5H4N2O/c8-3-5-1-6-4-7-2-5/h1-4H
InChIKey	FREJAOSUHFGDBW-UHFFFAOYSA-N
SMILES	C1=NC=C(C=O)C=N1
CAS DataBase Reference	10070-92-5(CAS DataBase Reference)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-43-22

Safety Statements

26-36/37/39-36-36/37

WGK Germany

WGK 3

HazardClass

IRRITANT

HS Code

2933599590

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

NFPA 704

	0
2		0

Pyrimidine-5-carboxaldehyde price More Price(73)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	CDS004733	pyrimidine-5-carboxaldehyde Aldrich^CPR		100 mg	$93.2	2026-04-30	Buy
Usbiological	286546	Pyrimidine-5-carboxaldehyde Asreported	10070-92-5	1g	$383	2026-06-03	Buy
Usbiological	286546	Pyrimidine-5-carboxaldehyde Asreported	10070-92-5	2g	$535	2026-06-03	Buy
Usbiological	286546	Pyrimidine-5-carboxaldehyde Asreported	10070-92-5	5g	$735	2026-06-03	Buy
Usbiological	286546	Pyrimidine-5-carboxaldehyde Asreported	10070-92-5	10g	$1012	2026-06-03	Buy

Product number	Packaging	Price	Buy
CDS004733	100 mg	$93.2	Buy
286546	1g	$383	Buy
286546	2g	$535	Buy
286546	5g	$735	Buy
286546	10g	$1012	Buy

Pyrimidine-5-carboxaldehyde Chemical Properties,Uses,Production

Uses

Pyrimidine-5-carboxaldehyde is used in the preparation of (S)- and (R)-pyrimidyl alkanol by reacting with diisopropylzinc and (n-butyl)ethyl(n-hexyl)(n-propyl)methane.

Synthesis

Under nitrogen, a solution of 5-bromopyrimidine (1 g, 6.3 mmol) in 60 mL anhydrous THF was added BuLi (2.5 M, 2.6 mL, 6.5 mmol) at -78° C. The resulting yellow solution was stirred for 20 min, after which ethyl formate (0.55 mL, 6.7 mmol) was added dropwise over 5 min. After 20 min, the reaction was quenched with 1.5 M THF/HCl solution (4.5 mL, 6.7 mmol). The cold bath was removed, and the reaction mixture was stirred for 1 h. THF was removed in vacco, 10 mL of water was then added. The mixture was extracted with CHCl3 (2*10 mL), and the combined organics were dried (MgSO4) and concentrated. The crude product was purified via flash column chromatography (5 per cent MeOH/CHCl3) to give 0.35 g (51 per cent) of the titled Pyrimidine-5-carboxaldehyde.

References

[1] Journal of medicinal chemistry, 2004, vol. 47, # 20, p. 4829 - 4837
[2] Patent: US2005/70712, 2005, A1. Location in patent: Page/Page column 42
[3] Patent: US2005/171131, 2005, A1. Location in patent: Page/Page column 41
[4] Patent: US9212138, 2015, B2. Location in patent: Page/Page column 42
[5] ChemMedChem, 2017, vol. 12, # 3, p. 257 - 270

Pyrimidine-5-carboxaldehyde synthesis

Synthesis of Pyrimidine-5-carboxaldehyde from 3-Pyridyl bromide and 5-Bromopyrimidine and Sodium carbonate and Ethyl formate

Pyrimidine-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Nitrogen Ethyl formate Tetrahydrofuran Diethyl ether Ethyl acetate

Hydrochloric acid 5-Bromopyrimidine Magnesium sulfate Petroleum ether n-Butyllithium

2,2-diethoxyacetic acid 5-Pyrimidinemethanol

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Preparation Products

α-Methyl-5-pyriMidineMethanol 2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE triflumezopyrim

Pyrimidine-5-carboxaldehyde Suppliers

Global( 320)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32998	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10817	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from Pyrimidine-5-carboxaldehyde manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	Pyrimidine-5-carboxaldehyde 10070-92-5	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2025-05-12	Pyrimidine-5-carboxaldehyde 10070-92-5		1kg	95%	5-10 MTs	PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
2021-07-13	Pyrimidine-5-carbaldehyde 10070-92-5	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Pyrimidine-5-carboxaldehyde
10070-92-5
$1.10
99.00%
Dideu Industries Group Limited

Pyrimidine-5-carboxaldehyde
10070-92-5
$0.00
95%
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Pyrimidine-5-carbaldehyde
10070-92-5
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Pyrimidine-5-carboxaldehyde Spectrum

Pyrimidine-5-carboxaldehyde(10070-92-5)¹HNMR

10070-92-5(Pyrimidine-5-carboxaldehyde)Related Search:

Formaldehyde Sulfadiazine Fluorocytosine Pyrimidine Uracil

Silver sulfadiazine 5-METHYLCYTOSINE PYRIMIDINE-4-CARBOXALDEHYDE Pyrimidine-5-boronic acid pinacol ester 2-Pyrimidinecarboxamide (6CI,7CI,9CI)

Pyrimidine-2-carboxylic acid 5-Pyrimidinecarboxylic acid Pyrrole-2-carboxaldehyde PYRROLE-2-CARBONITRILE Pyrrole-2-carboxylic acid

5-PYRIMIDINECARBOXAMIDE PYRIMIDINE-4-CARBOXYLIC ACID METHYL ESTER 4,6-PYRIMIDINE DICARBOXYLIC ACID

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RARECHEM AK ML 0565 PYRIMIDINE-5-CARBOXYALDEHYDE PYRIMIDINE-5-CARBOXALDEHYDE 5-PYRIMIDINECARBOXALDEHYDE 5-Pyrimidinecarboxaldehyde (7CI,8CI,9CI) 5-Pyrimidinecarbaldehyde Pyrimidine-5-carboxylaldehyde PyriMidin-5-carbaldehyde 5-Formylpyrimidine, 5-Formyl-1,3-diazine PyriMidine-5-carbaldehyde 5-ForMylpyriMidine Pyrimidine-5-carboxaldehyde ISO 9001：2015 REACH Pyrimidine-5-formaldehyde 5-FORMYLPYRIMIDINE PYRIMIDINE-5-CARBALDEHYDE 10070-92-5 Heterocycle-Pyrimidine series Aromatics Heterocycles PYRIMIDINE Aldehyde Building Blocks Pyrimidines Boronic Acid Heterocyclic Compounds