O-Phospho-L-threonine
- CAS No.
- 1114-81-4
- Chemical Name:
- O-Phospho-L-threonine
- Synonyms
- H-THR(PO3H2)-OH;O-Phosphothreonine;Threonine phosphate;O-Phospho-L-threonine;L-THREONINE O-PHOSPHATE;Oxo-Phospho-L-Threonine;L-Threonine, O-phosphono-;(2S,3R)-O-Phosphothreonine;O-Phospho-
L -threonine;L-Threonine dihydrogen phosphate
- CBNumber:
- CB2213596
- Molecular Formula:
- C4H10NO6P
- Molecular Weight:
- 199.1
- MDL Number:
- MFCD00069578
- MOL File:
- 1114-81-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 169 °C |
|---|---|
| Boiling point | 454.0±55.0 °C(Predicted) |
| Density | 1.671±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | NH4OH 1 M: 0.1 g/mL, clear, colorless |
| pka | 1.73±0.10(Predicted) |
| form | A solid |
| color | white |
| optical activity | -9.7°(C=0.01g/mI, H2O, 20°C, 589nm) |
| BRN | 1727078 |
| InChI | 1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1 |
| InChIKey | USRGIUJOYOXOQJ-GBXIJSLDSA-N |
| SMILES | C[C@@H](OP(O)(O)=O)[C@H](N)C(O)=O |
| FDA UNII | 3L4WX7B1EI |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
O-Phospho-L-threonine price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P1053 | O-Phospho-L-threonine | 1114-81-4 | 250mg | $84.5 | 2023-06-20 | Buy |
| Sigma-Aldrich | P1053 | O-Phospho-L-threonine | 1114-81-4 | 1g | $269 | 2023-06-20 | Buy |
| Cayman Chemical | 35057 | O-Phospho-L-Threonine ≥95% | 1114-81-4 | 100mg | $46 | 2026-04-30 | Buy |
| Cayman Chemical | 35057 | O-Phospho-L-Threonine ≥95% | 1114-81-4 | 250mg | $85 | 2026-04-30 | Buy |
| Cayman Chemical | 35057 | O-Phospho-L-Threonine ≥95% | 1114-81-4 | 500mg | $157 | 2026-04-30 | Buy |
O-Phospho-L-threonine Chemical Properties, Uses, Production
Uses
O-Phospho-L-threonine is a threonine derivative[1].
Definition
ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).
Biochem/physiol Actions
O-Phospho-L-threonine is an amino acid derivative.
IC 50
Human Endogenous Metabolite
Purification Methods
Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368
O-Phospho-L-threonine Preparation Products And Raw materials
O-Phospho-L-threonine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Halyn Biotech Co.,Ltd. | 0518-85253680 19051883673 | export@halynbio.com | China | 35 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11775 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9259 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
View Latest Price from O-Phospho-L-threonine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | O-PHOSPHO-L-THREONINE
1114-81-4
|
1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd |
-
- O-PHOSPHO-L-THREONINE
1114-81-4
- $0.10
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
