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CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE structure

CAS No.: 13149-00-3

Chemical Name:: CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

Synonyms: HHPA;CIS-CYCLOHEXANE-1,2-DICARBOXYLIC ANHYDRIDE;CIS-HHPA;Perospirone Impurity 6;Paracetamol Impurity 36;CIS-HEXAHYDROPHTHALIC ANHYDRIDE;Hexahydro-2-benzofuran-1,3-dione;HEXAHYDROPHTHALIC ACID ANHYDRIDE;HHPA,Hexahydrophthalic anhydride;cis-Hexahydroisobenzofuran-1,3-dione

CBNumber:: CB2228246

Molecular Formula:: C8H10O3

Molecular Weight:: 154.16

MDL Number:: MFCD00005926

MOL File:: 13149-00-3.mol

MSDS File:: SDS

Last updated:2026-02-10 11:39:28

Product description	Number	Pack Size	Price
cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	C0478	25g	$17
cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	C0478	100g	$33
cis-Hexahydroisobenzofuran-1,3-dione 97%	CM158620	1000g	$69
cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	C0478	500g	$65
(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione	H294030	25g	$185
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CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Properties

Melting point	32-34 °C(lit.)
Boiling point	158 °C17 mm Hg(lit.)
Density	1.23
refractive index	1.4750 (estimate)
Flash point	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Crystalline Low Melting Solid
color	White to almost white
Sensitive	Moisture Sensitive
BRN	83214
Stability	Moisture Sensitive
Substances of Very High Concern (SVHC) Candidate List	cis-cyclohexane-1,2-dicarboxylic anhydride (13149-00-3)
CAS DataBase Reference	13149-00-3(CAS DataBase Reference)
FDA UNII	B52Z7TNV87

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS08

Signal word

Danger

Hazard statements

H317-H318-H334

Precautionary statements

P261-P272-P280-P284-P302+P352+P333+P313+P363-P304+P340+P342+P311-P305+P351+P338+P310-P501-P280a-P304+P340-P305+P351+P338-P501a

Hazard Codes

Risk Statements

41-42/43

Safety Statements

23-24-26-37/39

WGK Germany

10-21

HS Code

29420000

NFPA 704

	1
2		0

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C0478	cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	13149-00-3	25g	$17	2026-04-30	Buy
TCI Chemical	C0478	cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	13149-00-3	100g	$33	2026-04-30	Buy
Chemenu	CM158620	cis-Hexahydroisobenzofuran-1,3-dione 97%	13149-00-3	1000g	$69	2026-05-20	Buy
TCI Chemical	C0478	cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC)	13149-00-3	500g	$65	2026-04-30	Buy
TRC	H294030	(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione	13149-00-3	25g	$185	2021-12-16	Buy

Product number	Packaging	Price	Buy
C0478	25g	$17	Buy
C0478	100g	$33	Buy
CM158620	1000g	$69	Buy
C0478	500g	$65	Buy
H294030	25g	$185	Buy

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Chemical Properties,Uses,Production

Chemical Properties

white to almost white cryst. low melting solid

Uses

(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.

Purification Methods

It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.]

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE synthesis

Synthesis of CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE from (1R,2R)-(-)-1,2-Cyclohexanedicarboxylic acid

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Tetrachlorophthalic anhydride trans-1,2-Cyclohexanedicarboxylic acid (1R,2R)-(-)-1,2-Cyclohexanedicarboxylic acid (+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE cis-Hexahydrophthalic acid

cis-1,2,3,6-Tetrahydrophthalic anhydride

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Preparation Products

2-hydroxyhexahydro-1H-isoindole-1,3(2H)-dione

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Suppliers

Global( 223)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Puyang Huicheng Electronic Materials Co., Ltd.	+86-0393-+86-0393-8910800 +8615839383373	info@huichengchem.com	China	530	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Shanghai Daeyeon Chemicals Co., Ltd	021-64478606 +8615900664856	daeyeon001@vip.163.com	China	2062	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Baoji Guokang Healthchem Co., Ltd.	+86-0917-3909592 +86-13892490616	gksales1@gk-bio.com	China	9078	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Puyang Huicheng Electronic Materials Co., Ltd.	58
SIMAGCHEM CORP	58
Shanghai Daeyeon Chemicals Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Baoji Guokang Healthchem Co., Ltd.	58

View Lastest Price from CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE 13149-00-3	US $0.00-0.00 / KG	1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2021-07-13	Cis-1,2-Cyclohexanedicarboxylic Anhydride 13149-00-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	Cis-1,2-Cyclohexanedicarboxylic Anhydride 13149-00-3	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
13149-00-3
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Spectrum

CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)MS CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)¹HNMR CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)¹³CNMR CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)IR1 CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)IR2 CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)IR3 CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE(13149-00-3)Raman

13149-00-3(CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE)Related Search:

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2-Cyano-3-ethoxy-2-proenoicacidethylester 3-Isobenzofuranedione,hexahydro-,cis-1 cis-cyclohexane-1,2-dicarboxylicacidanhydride Hexahydro-2-benzofuran-1,3-dione (3aS)-3aα,4,5,6,7,7aα-Hexahydroisobenzofuran-1,3-dione (3aα,7aα)-Octahydroisobenzofuran-1,3-dione 3aα,4,5,6,7,7aα-Hexahydroisobenzofuran-1,3-dione (1R)-Cyclohexane-1β,2α-dicarboxylic anhydride (3aR)-1,3,3aβ,4,5,6,7,7aα-Octahydroisobenzofuran-1,3-dione (3aR,7aR)-3a,4,5,6,7,7a-Hexahydroisobenzofuran-1,3-dione cis-1,2-Cyclohexanedicarboxylic anhydride,99% cis-1,2-Cyclohexanedicarboxylic anhydride, 98%% cis-1,2-Cyclohexanedicarboxylic anhydride, 99% 1KG cis-1,2-Cyclohexanedicarboxylic anhydride, 99% 250GR cis-1,2-Cyclohexanedicarboxylic anhydride, 99% 5GR cis-Hexahydroisobenzofuran-1,3-dione HHPA),cis-1,2-Cyclohexanedicarboxylican cis-Cyclohexan-1,2-dicarbonsureanhydrid CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE (HHPA) 1,3-Isobenzofurandione, hexahydro-, (3aR,7aS)-rel- CIS-1,2-CYCLOHEXANEDECARBOXYLICANHYDRIDE CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE CIS-HEXAHYDROPHTHALIC ANHYDRIDE CIS-HHPA CIS-CYCLOHEXANE-1,2-DICARBOXYLIC ANHYDRIDE HEXAHYDROPHTHALIC ACID ANHYDRIDE HHPA HHPA,Hexahydrophthalic anhydride (3aR,7aS)-Hexahydro-isobenzofuran-1,3-dione 1,3-Isobenzofurandione, hexahydro-, cis- cis-Hexahydrophthalic anhydride cis-HHPA cis-1,2-CyclohexanedicarboxylicAnhydride> 1,2-Cyclohexanedicarboxylic anhydride, cis CYCLOHEXANE-1,2-DICARBOXYLIC ANHYDRI Perospirone Impurity 6 (3aS,7aR)-3a,4,5,6,7,7a-hexahydro-2-benzofuran-1,3-dione Paracetamol Impurity 36 cis-1,2-Cyclohexanedicarboxylic acid anhydride 13149-00-3 Building Blocks Carbonyl Compounds Carboxylic Acid Anhydrides Organic Building Blocks Pharmaceutical Intermediates