cis-1,2-Cyclohexanedicarboxylic anhydride
- CAS No.
- 13149-00-3
- Chemical Name:
- cis-1,2-Cyclohexanedicarboxylic anhydride
- Synonyms
- HHPA;CIS-CYCLOHEXANE-1,2-DICARBOXYLIC ANHYDRIDE;CIS-HHPA;Perospirone Impurity 6;Paracetamol Impurity 36;CIS-HEXAHYDROPHTHALIC ANHYDRIDE;Hexahydro-2-benzofuran-1,3-dione;HEXAHYDROPHTHALIC ACID ANHYDRIDE;HHPA,Hexahydrophthalic anhydride;cis-Hexahydroisobenzofuran-1,3-dione
- CBNumber:
- CB2228246
- Molecular Formula:
- C8H10O3
- Molecular Weight:
- 154.16
- MDL Number:
- MFCD00005926
- MOL File:
- 13149-00-3.mol
- MSDS File:
- SDS
| Melting point | 32-34 °C(lit.) |
|---|---|
| Boiling point | 158 °C17 mm Hg(lit.) |
| Density | 1.23 |
| refractive index | 1.4750 (estimate) |
| Flash point | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Crystalline Low Melting Solid |
| color | White to almost white |
| Sensitive | Moisture Sensitive |
| BRN | 83214 |
| Exposure limits | TLV-CEILING: 0.005 mg/m3, Inhalable fraction and vapor |
| Stability | Moisture Sensitive |
| Substances of Very High Concern (SVHC) Candidate List | cis-cyclohexane-1,2-dicarboxylic anhydride (13149-00-3) |
| CAS DataBase Reference | 13149-00-3(CAS DataBase Reference) |
| FDA UNII | B52Z7TNV87 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H334 | |||||||||
| Precautionary statements | P261-P272-P280-P284-P302+P352+P333+P313+P363-P304+P340+P342+P311-P305+P351+P338+P310-P501-P280a-P304+P340-P305+P351+P338-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 41-42/43 | |||||||||
| Safety Statements | 23-24-26-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29420000 | |||||||||
| NFPA 704 |
|
cis-1,2-Cyclohexanedicarboxylic anhydride price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0478 | cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC) | 13149-00-3 | 25g | $17 | 2026-04-30 | Buy |
| TCI Chemical | C0478 | cis-1,2-Cyclohexanedicarboxylic Anhydride >99.0%(GC) | 13149-00-3 | 100g | $33 | 2026-04-30 | Buy |
| TRC | TRC-H294030-5G | (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione | 13149-00-3 | 5g | $183 | 2026-06-03 | Buy |
| TRC | TRC-H294030-50G | (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione | 13149-00-3 | 50g | $293 | 2026-06-03 | Buy |
| TRC | TRC-H294030-25G | (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione | 13149-00-3 | 25g | $252 | 2026-06-03 | Buy |
cis-1,2-Cyclohexanedicarboxylic anhydride Chemical Properties,Uses,Production
Chemical Properties
white to almost white cryst. low melting solid
Uses
(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.
Purification Methods
It has been obtained by heating the trans-acid or anhydride at 200o. Crystallise it from *C6H6/Et2O or distil it. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Abell J Org Chem 22 769 1957, Beilstein 17 II 452, 17 III/IV 5931.]


cis-1,2-Cyclohexanedicarboxylic anhydride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Puyang Huicheng Electronic Material Co. Ltd. | 0393-0393-8910800 15039333257 | info@huichengchem.com | China | 588 | 64 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
View Lastest Price from cis-1,2-Cyclohexanedicarboxylic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
13149-00-3
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
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2021-07-13 | Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
![]() |
2021-07-10 | Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- CIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
13149-00-3
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-

- Cis-1,2-Cyclohexanedicarboxylic Anhydride
13149-00-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
cis-1,2-Cyclohexanedicarboxylic anhydride Spectrum
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