cis-1,4-Cyclohexanedicarboxybic acid
- CAS No.
- 619-81-8
- Chemical Name:
- cis-1,4-Cyclohexanedicarboxybic acid
- Synonyms
- CIS-1,4-CYCLOHEXANEDICARBOXYLIC ACID;cis-Cyclohexane-1,4-dicarboxylic acid;Cyclohexanedicarboxylicacid;CIS-HEXAHYDROTEREPHTHALIC ACID;Cis-1,4-CyclohexanedicarboxylicAci;CIS-1,4-CYCLOHEXANEDICARBOXYBIC ACID;1,4-Cyclohexanedicarboxylic acid, cis-;cis-1,4-Cyclohexanedicarboxylic Acid >rac-(1s,4s)-cyclohexane-1,4-dicarboxylic acid
- CBNumber:
- CB7135648
- Molecular Formula:
- C8H12O4
- Molecular Weight:
- 172.18
- MDL Number:
- MFCD00064950
- MOL File:
- 619-81-8.mol
- MSDS File:
- SDS
| Melting point | 168 °C |
|---|---|
| Boiling point | 384.1±35.0 °C(Predicted) |
| Density | 1.3200 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Ethanol,Ether,Chloroform,Methanol |
| pka | 4.51±0.25(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| CAS DataBase Reference | 619-81-8(CAS DataBase Reference) |
| FDA UNII | 68QED0R44U |
| NIST Chemistry Reference | cis-Hexahydroterephthalic acid(619-81-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| HS Code | 29172090 | |||||||||
| NFPA 704 |
|
cis-1,4-Cyclohexanedicarboxybic acid price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0789 | cis-1,4-Cyclohexanedicarboxylic Acid >90.0%(GC) | 619-81-8 | 25g | $94 | 2026-04-30 | Buy |
| TCI Chemical | C0789 | cis-1,4-Cyclohexanedicarboxylic Acid >90.0%(GC) | 619-81-8 | 100g | $257 | 2026-04-30 | Buy |
| AK Scientific | U276 | cis-1,4-Cyclohexanedicarboxylic acid 90% | 619-81-8 | 1g | $17 | 2026-06-04 | Buy |
| AK Scientific | U276 | cis-1,4-Cyclohexanedicarboxylic acid 90% | 619-81-8 | 5g | $48 | 2026-06-04 | Buy |
| AK Scientific | U276 | cis-1,4-Cyclohexanedicarboxylic acid 90% | 619-81-8 | 25g | $138 | 2026-06-04 | Buy |
cis-1,4-Cyclohexanedicarboxybic acid Chemical Properties, Uses, Production
Definition
ChEBI: 1,4-cyclohexanedicarboxylic acid is a dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4.
Synthesis
100-21-0
619-81-8
The general procedure for synthesizing cis-1,4-cyclohexanedicarboxylic acid from terephthalic acid was as follows: 200 g of terephthalic acid, 15 g of the Pd-Pt/C catalyst of Examples 1 to 14 and 1000 g of water were added to an autoclave, and stirring was initiated. The reaction system was first purged with nitrogen three times, followed by hydrogen replacement three times. The hydrogen pressure was adjusted to 4 MPa, the reaction temperature was maintained at 200°C, and hydrogen was continuously supplied under this condition for 3 hours. At the end of the reaction, the catalyst was removed by filtration while hot. The filtrate was cooled and filtered again to collect the filter cake. The filter cake was dried at 120°C to obtain the solid product. The solid product was analyzed by liquid chromatography to determine the contents of 1,4-cyclohexanedicarboxylic acid and trans-1,4-cyclohexanedicarboxylic acid therein, from which the yield of 1,4-cyclohexanedicarboxylic acid and the selectivity of trans-1,4-cyclohexanedicarboxylic acid were calculated, and the specific results are listed in Table 2.
References
[1] Patent: CN103769089, 2016, B. Location in patent: Paragraph 0029; 0030
[2] RSC Advances, 2017, vol. 7, # 30, p. 18178 - 18188
[3] Patent: CN105237341, 2016, A. Location in patent: Paragraph 0014
[4] Patent: KR2017/36493, 2017, A. Location in patent: Paragraph 0057; 0058; 0059
[5] Patent: KR2018/35585, 2018, A. Location in patent: Paragraph 0117-0121; 0145; 0146
cis-1,4-Cyclohexanedicarboxybic acid Preparation Products And Raw materials
Raw materials
Preparation Products
cis-1,4-Cyclohexanedicarboxybic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Shanghai Targsense Scientific Co., Ltd. | 18916626092 | targsense@qq.com | China | 110 | 65 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from cis-1,4-Cyclohexanedicarboxybic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
|
1kg | 99% | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
![]() |
2020-01-09 | cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
|
$1.00 | 1KG | 85.0-99.8% | 20tons | Career Henan Chemical Co |
-

- cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
- $1.00
- 85.0-99.8%
- Career Henan Chemical Co
cis-1,4-Cyclohexanedicarboxybic acid Spectrum
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