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cis-1,4-Cyclohexanedicarboxybic acid

CAS No.
619-81-8
Chemical Name:
cis-1,4-Cyclohexanedicarboxybic acid
Synonyms
CIS-1,4-CYCLOHEXANEDICARBOXYLIC ACID;cis-Cyclohexane-1,4-dicarboxylic acid;Cyclohexanedicarboxylicacid;CIS-HEXAHYDROTEREPHTHALIC ACID;Cis-1,4-CyclohexanedicarboxylicAci;CIS-1,4-CYCLOHEXANEDICARBOXYBIC ACID;1,4-Cyclohexanedicarboxylic acid, cis-;cis-1,4-Cyclohexanedicarboxylic Acid >rac-(1s,4s)-cyclohexane-1,4-dicarboxylic acid
CBNumber:
CB7135648
Molecular Formula:
C8H12O4
Molecular Weight:
172.18
MDL Number:
MFCD00064950
MOL File:
619-81-8.mol
MSDS File:
SDS
Last updated:2026-05-28 02:58:05

cis-1,4-Cyclohexanedicarboxybic acid Properties

Melting point 168 °C
Boiling point 384.1±35.0 °C(Predicted)
Density 1.3200
storage temp. Sealed in dry,Room Temperature
solubility soluble in Ethanol,Ether,Chloroform,Methanol
pka 4.51±0.25(Predicted)
form powder to crystal
color White to Almost white
CAS DataBase Reference 619-81-8(CAS DataBase Reference)
FDA UNII 68QED0R44U
NIST Chemistry Reference cis-Hexahydroterephthalic acid(619-81-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
HS Code  29172090
NFPA 704
0
1 0

cis-1,4-Cyclohexanedicarboxybic acid price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C0789 cis-1,4-Cyclohexanedicarboxylic Acid >90.0%(GC) 619-81-8 25g $94 2026-04-30 Buy
TCI Chemical C0789 cis-1,4-Cyclohexanedicarboxylic Acid >90.0%(GC) 619-81-8 100g $257 2026-04-30 Buy
AK Scientific U276 cis-1,4-Cyclohexanedicarboxylic acid 90% 619-81-8 1g $17 2026-06-04 Buy
AK Scientific U276 cis-1,4-Cyclohexanedicarboxylic acid 90% 619-81-8 5g $48 2026-06-04 Buy
AK Scientific U276 cis-1,4-Cyclohexanedicarboxylic acid 90% 619-81-8 25g $138 2026-06-04 Buy
Product number Packaging Price Buy
C0789 25g $94 Buy
C0789 100g $257 Buy
U276 1g $17 Buy
U276 5g $48 Buy
U276 25g $138 Buy

cis-1,4-Cyclohexanedicarboxybic acid Chemical Properties, Uses, Production

Definition

ChEBI: 1,4-cyclohexanedicarboxylic acid is a dicarboxylic acid that is cyclohexane substituted by carboxy groups at positions 1 and 4.

Synthesis

Terephthalic acid

100-21-0

cis-1,4-Cyclohexanedicarboxybic acid

619-81-8

The general procedure for synthesizing cis-1,4-cyclohexanedicarboxylic acid from terephthalic acid was as follows: 200 g of terephthalic acid, 15 g of the Pd-Pt/C catalyst of Examples 1 to 14 and 1000 g of water were added to an autoclave, and stirring was initiated. The reaction system was first purged with nitrogen three times, followed by hydrogen replacement three times. The hydrogen pressure was adjusted to 4 MPa, the reaction temperature was maintained at 200°C, and hydrogen was continuously supplied under this condition for 3 hours. At the end of the reaction, the catalyst was removed by filtration while hot. The filtrate was cooled and filtered again to collect the filter cake. The filter cake was dried at 120°C to obtain the solid product. The solid product was analyzed by liquid chromatography to determine the contents of 1,4-cyclohexanedicarboxylic acid and trans-1,4-cyclohexanedicarboxylic acid therein, from which the yield of 1,4-cyclohexanedicarboxylic acid and the selectivity of trans-1,4-cyclohexanedicarboxylic acid were calculated, and the specific results are listed in Table 2.

References

[1] Patent: CN103769089, 2016, B. Location in patent: Paragraph 0029; 0030
[2] RSC Advances, 2017, vol. 7, # 30, p. 18178 - 18188
[3] Patent: CN105237341, 2016, A. Location in patent: Paragraph 0014
[4] Patent: KR2017/36493, 2017, A. Location in patent: Paragraph 0057; 0058; 0059
[5] Patent: KR2018/35585, 2018, A. Location in patent: Paragraph 0117-0121; 0145; 0146

cis-1,4-Cyclohexanedicarboxybic acid Preparation Products And Raw materials

cis-1,4-Cyclohexanedicarboxybic acid Suppliers

Global Suppliers ( 122)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shanghai Targsense Scientific Co., Ltd. 18916626092 targsense@qq.com China 110 65
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75

View Latest Price from cis-1,4-Cyclohexanedicarboxybic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
cis-1,4-Cyclohexanedicarboxybic acid pictures 2026-02-02 cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
1kg 99% 2000tons Shaanxi Dideu Medichem Co. Ltd
cis-1,4-Cyclohexanedicarboxybic acid pictures 2020-01-09 cis-1,4-Cyclohexanedicarboxybic acid
619-81-8
$1.00 1KG 85.0-99.8% 20tons Career Henan Chemical Co
1,4-Cyclohexanedicarboxylic acid, cis- CIS-HEXAHYDROTEREPHTHALIC ACID CIS-1,4-CYCLOHEXANEDICARBOXYBIC ACID CIS-1,4-CYCLOHEXANEDICARBOXYLIC ACID Cyclohexanedicarboxylicacid cis-Cyclohexane-1,4-dicarboxylic acid cis-1,4-Cyclohexanedicarboxylic Acid > Cis-1,4-CyclohexanedicarboxylicAci rac-(1s,4s)-cyclohexane-1,4-dicarboxylic acid 619-81-8 4-Substituted Cyclohexanecarboxylic Acids chiral 4-Substituted Cyclohexanecarboxylic Acids