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2-Chloro-5-methylsulfanylbenzoic acid

2-Chloro-5-methylsulfanylbenzoic acid structure

CAS No.: 51546-12-4

Chemical Name:: 2-Chloro-5-methylsulfanylbenzoic acid

Synonyms: TOME-1;LABOTEST-BB LT00452880;Gene-rich cluster protein C8;Trigger of mitotic entry protein 1;2-CHLORO-5-(METHYLTHIO)BENZOIC ACID;2-Chloro-5-methylsulfanylbenzoicaci;2-CHLORO-5-METHYLSULFANYLBENZOIC ACID;Benzoic acid, 2-chloro-5-(methylthio)-;Cell division cycle-associated protein 3;2-CHLORO-5-(METHYLTHIO)BENZOIC ACID TECH 98.0%

CBNumber:: CB2228534

Molecular Formula:: C8H7ClO2S

Molecular Weight:: 202.66

MDL Number:: MFCD00009721

MOL File:: 51546-12-4.mol

MSDS File:: SDS

Last updated:2026-01-13 11:17:01

Product description	Number	Pack Size	Price
2-Chloro-5-(methylthio)benzoic acid technical grade, 96%	245380	10g	$327
Anti-CDCA3, C-Terminal antibody produced in rabbit affinity isolated antibody	SAB4503278	100μG	$485
2-Chloro-5-(methylthio)benzoic acid technical grade, 96%	245380	50g	$600
2-Chloro-5-(methylthio)benzoic acid	184513	1.00g	$120
2-Chloro-5-(methylthio)benzoic acid	184513	5.00g	$380
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2-Chloro-5-methylsulfanylbenzoic acid Properties

Melting point	136-137 °C (lit.)
Boiling point	342.4±32.0 °C(Predicted)
Density	1.42
storage temp.	Sealed in dry,Room Temperature
pka	2.74±0.25(Predicted)
form	solid
Appearance	White to off-white Solid
biological source	rabbit
InChI	1S/C8H7ClO2S/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)
InChIKey	HJDZJDJRUVAYTR-UHFFFAOYSA-N
SMILES	CSc1ccc(Cl)c(c1)C(O)=O
UNSPSC Code	12352203
NACRES	NA.41

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs	Respiratory system
PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39-36
WGK Germany	3
HS Code	2930909899
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

2-Chloro-5-methylsulfanylbenzoic acid price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	245380	2-Chloro-5-(methylthio)benzoic acid technical grade, 96%	51546-12-4	10g	$327	2026-04-30	Buy
Sigma-Aldrich	SAB4503278	Anti-CDCA3, C-Terminal antibody produced in rabbit affinity isolated antibody	51546-12-4	100μG	$485	2023-01-07	Buy
Sigma-Aldrich	245380	2-Chloro-5-(methylthio)benzoic acid technical grade, 96%	51546-12-4	50g	$600	2023-01-07	Buy
Matrix Scientific	184513	2-Chloro-5-(methylthio)benzoic acid	51546-12-4	1.00g	$120	2026-05-18	Buy
Matrix Scientific	184513	2-Chloro-5-(methylthio)benzoic acid	51546-12-4	5.00g	$380	2026-05-18	Buy

Product number	Packaging	Price	Buy
245380	10g	$327	Buy
SAB4503278	100μG	$485	Buy
245380	50g	$600	Buy
184513	1.00g	$120	Buy
184513	5.00g	$380	Buy

2-Chloro-5-methylsulfanylbenzoic acid Chemical Properties,Uses,Production

Uses

2-Chloro-5-(methylthio)benzoic acid may be used in chemical synthesis studies.

Synthesis

Benzoic acid, 2-chloro-5-(methylthio)-, methyl ester

886973-19-9

544-92-3

Benzoic acid, 2-cyano-5-(methylthio)-, methyl ester

127510-97-8

51546-12-4

Methyl 2-chloro-5-(methylthio)benzoate (23.2 g, 106.9 mmol) and cuprous cyanide (19.2 g, 213.8 mmol) were dissolved in 100 mL of N-methylpyrrolidone. The reaction mixture was heated at 160 °C for 72 hours. The progress of the reaction was monitored by LCMS, which showed the presence of cyanide ester and hydrolyzed acid in a 1:1 ratio. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently treated with 250 mL of water and 300 mL of ethyl acetate and filtered through diatomaceous earth. After separating the organic and aqueous phases, the aqueous phase was extracted with 2 x 250 mL of ethyl acetate. The organic phases were combined, washed with 250 mL of water, dried over MgSO4 and concentrated to give an oily crude product. The crude product was purified by combi fast silica gel column chromatography using a hexane solution of 0-20% ethyl acetate as eluent, resulting in methyl 2-cyano-5-(methylthio)benzoate (6.14 g, 28% yield) as a white solid.The LCMS analysis showed the following: retention time (Rt) = 2.42 min; mass-to-charge ratio (m/z) [M + H]+ = 208.

References

[1] Patent: WO2006/67462, 2006, A1. Location in patent: Page/Page column 61

2-Chloro-5-methylsulfanylbenzoic acid Preparation Products And Raw materials

Raw materials

Benzoic acid, 2-chloro-5-(methylthio)-, methyl ester Copper(I) Cyanide

Preparation Products

2-Chloro-5-methylsulfanylbenzoic acid Suppliers

Global( 82)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Nanjing jinheyou Trading Co., Ltd.	15705188088	admin@jheyou.com	CHINA	1268	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	10000	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49967	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
Nanjing jinheyou Trading Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from 2-Chloro-5-methylsulfanylbenzoic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-02-18	2-Chloro-5-methylsulfanylbenzoic acid 51546-12-4	US $7.00 / KG	1KG	99%	100kg	Career Henan Chemical Co
	2019-11-08	2-Chloro-5-methylsulfanylbenzoic acid 51546-12-4	US $0.00 / g	1g	98%min	20kg/month	Nanjing jinheyou Trading Co., Ltd.

2-Chloro-5-methylsulfanylbenzoic acid
51546-12-4
US $7.00 / KG
99%
Career Henan Chemical Co

2-Chloro-5-methylsulfanylbenzoic acid
51546-12-4
US $0.00 / g
98%min
Nanjing jinheyou Trading Co., Ltd.

2-Chloro-5-methylsulfanylbenzoic acid Spectrum

2-Chloro-5-methylsulfanylbenzoic acid(51546-12-4)MS 2-Chloro-5-methylsulfanylbenzoic acid(51546-12-4)¹HNMR 2-Chloro-5-methylsulfanylbenzoic acid(51546-12-4)¹³CNMR 2-Chloro-5-methylsulfanylbenzoic acid(51546-12-4)IR1 2-Chloro-5-methylsulfanylbenzoic acid(51546-12-4)IR2

51546-12-4(2-Chloro-5-methylsulfanylbenzoic acid)Related Search:

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LABOTEST-BB LT00452880 2-CHLORO-5-(METHYLTHIO)BENZOIC ACID 2-CHLORO-5-METHYLSULFANYLBENZOIC ACID 2-CHLORO-5-(METHYLTHIO)BENZOIC ACID TECH 98.0% 2-CHLORO-5-(METHYLTHIO)BENZOIC ACID, TEC H., 96% Benzoic acid, 2-chloro-5-(methylthio)- Anti-CDCA3, C-Terminal antibody produced in rabbit Cell division cycle-associated protein 3 3-Carboxy-4-chlorothioanisole, 2-Chloro-5-(methylsulphanyl)benzoic acid 2-Chloro-5-(Methylthio)benzoic acid technical grade, 96% Gene-rich cluster protein C8 TOME-1 Trigger of mitotic entry protein 1 2-Chloro-5-methylsulfanylbenzoicaci 51546-12-4 C8H7O2ClS ClC6H3SCH3CO2H Organic Building Blocks Building Blocks C8 Carboxylic Acids Carbonyl Compounds C8 Carbonyl Compounds Carboxylic Acids