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N-(3-Bromopropyl)phthalimide

N-(3-Bromopropyl)phthalimide structure

CAS No.: 5460-29-7

Chemical Name:: N-(3-Bromopropyl)phthalimide

Synonyms: 2-(3-BROMO-PROPYL)-ISOINDOLE-1,3-DIONE;2-(3-BroMopropyl)isoindoline-1.3-dione;AKOS 226-47;AURORA KA-570;TIMTEC-BB SBB003049;LABOTEST-BB LT00455358;(3-bromopropyl)phthalimide;N-(3-Bromopropyl)phthahmide;N-(3-bromopropyl)pthalimide;GAMMA-BROMOPROPYLPHTHALIMIDE

CBNumber:: CB2237116

Molecular Formula:: C11H10BrNO2

Molecular Weight:: 268.11

MDL Number:: MFCD00005904

MOL File:: 5460-29-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:50:33

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N-(3-Bromopropyl)phthalimide Properties

Melting point	72-74 °C(lit.)
Boiling point	361℃
Density	1.578
refractive index	1.6320 (estimate)
Flash point	172℃
storage temp.	Inert atmosphere,Room Temperature
solubility	<1g/l
form	Crystalline Powder or Crystals
pka	-2.21±0.20(Predicted)
color	White to light beige
BRN	157547
InChI	InChI=1S/C11H10BrNO2/c12-6-3-7-13-10(14)8-4-1-2-5-9(8)11(13)15/h1-2,4-5H,3,6-7H2
InChIKey	VKJCJJYNVIYVQR-UHFFFAOYSA-N
SMILES	C1(=O)C2=C(C=CC=C2)C(=O)N1CCCBr
CAS DataBase Reference	5460-29-7(CAS DataBase Reference)
FDA UNII	VQG2G776PS
UNSPSC Code	12352111
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Risk Statements

36/37/38

Safety Statements

22-24/25

WGK Germany

HS Code

29251900

Storage Class

11 - Combustible Solids

NFPA 704

	1
2		0

N-(3-Bromopropyl)phthalimide price More Price(74)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B80003	N-(3-Bromopropyl)phthalimide 98%	5460-29-7	25g	$52.9	2026-04-30	Buy
Sigma-Aldrich	B80003	N-(3-Bromopropyl)phthalimide 98%	5460-29-7	100g	$128	2026-04-30	Buy
TCI Chemical	B1328	N-(3-Bromopropyl)phthalimide >98.0%(HPLC)(N)	5460-29-7	25g	$58	2026-04-30	Buy
TCI Chemical	B1328	N-(3-Bromopropyl)phthalimide >98.0%(HPLC)(N)	5460-29-7	500g	$619	2026-04-30	Buy
Usbiological	239899	N-(3-Bromopropyl)phthalimide 98+% ≥98%		25g	$177	2026-06-03	Buy

Product number	Packaging	Price	Buy
B80003	25g	$52.9	Buy
B80003	100g	$128	Buy
B1328	25g	$58	Buy
B1328	500g	$619	Buy
239899	25g	$177	Buy

N-(3-Bromopropyl)phthalimide Chemical Properties, Uses, Production

Chemical Properties

white powder

Uses

N-(3-Bromopropyl)phthalimide is used in synthesis of several organic compounds including that of flavonoid derivatives which act as selective ABCC1 modulators with potential use as pharmacological tools for investigation of the role of ABCC1. It is also used in the synthesis of Hederagenin which is a triterpene template for the development of new antitumor compounds.

reaction suitability

reagent type: cross-linking reagent

Synthesis

1074-82-4

109-64-8

5460-29-7

In 50 mL of DMF, 0.025 mol of phthalimide potassium salt, 0.10 mol of 1,3-dibromopropane and 0.5 g of TBAB were added and the reaction was carried out at 70°C for 2.0 hours. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water and extracted with ethyl acetate. The organic phase was sequentially washed with water, dried, concentrated and allowed to stand overnight to give 5.91 g of N-(3-bromopropyl)phthalimide as a white solid with a melting point of 70-73°C and a yield of 88.3%.

Purification Methods

Place it in a Soxhlet and extract it with Et2O, whereby the bis-phthalimido impurity is not extracted. Evaporate the Et2O and recrystallise the residue from EtOH, aqueous EtOH or pet ether. [Gabriel & Weiner Chem Ber 21 2669 1888, Gaudry Can J Chem 31 1060 1953, Beilstein 21/10 V 1277.]

References

[1] Patent: CN107382980, 2017, A. Location in patent: Paragraph 0035; 0036; 0037; 0038
[2] Patent: CN107540647, 2018, A. Location in patent: Paragraph 0049-0051
[3] European Journal of Medicinal Chemistry, 2018, vol. 149, p. 69 - 78
[4] Chemistry - A European Journal, 2014, vol. 20, # 6, p. 1530 - 1538
[5] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 7, p. 1223 - 1227

N-(3-Bromopropyl)phthalimide Preparation Products And Raw materials

Raw materials

N-(3-Hydroxypropyl)phthalimide 1H-Isoindol-1-one, 3-hydroxy- SODIUM PHTHALIMIDE Potassium phthalimide 1,3-Dibromopropane

N,N-Dimethylformamide Tetrabutylammomium bromide

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Preparation Products

N,N-Dibutyl-1,3-propanediamine N-(3-Aminopropyl)morpholine N,N-dipropylpropane-1,3-diamine 1-(3-Aminopropyl)piperidine 2-[3-(pyridin-2-ylsulfanyl)propyl]-2,3-dihydro-1H-isoindole-1,3-dione

2-(3-(3,5-Dimethoxyphenoxy)Propyl)Isoindoline-1,3-Dione {[3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propyl]sulfanyl}methanimidamide hydrobromide 4-[3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propoxy]benzaldehyde Ethyl 2-(3-N-phthalimidopropyl)acetoacetate Diethyl [3-(N-phthalimido)propyl]phosphonate, 97%

2-(3-(Methylthio)propyl)isoindoline-1,3-dione

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N-(3-Bromopropyl)phthalimide Suppliers

Global Suppliers ( 336)

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Highfine Biotech Co., Ltd	0512-69209928 18796809688	zhouyingxiang@highfine.com	China	472	75
Anhui Yongsheng Pharmaceutical Technology Co., Ltd	3307 18017383231	983544897@qq.com	China	943	58
Shandong Libixi Biopharmaceutical Technology Co., Ltd.	15318973357; 15318973357	1460285141@qq.com	China	9642	58
Shanghai Sunway Pharmaceutical Technology Co., Ltd	13761987713	hxzheng@sunwaypharm.cn	China	8663	57
Suzhou Sino Rare Chemical Co., Ltd.	0512-62857507	sales@sinorarechem.com	China	999	58
Shanghai Chiyuan Technology Co., Ltd	13818304948	55992407@qq.com	China	124	58
Shanghai Qiao Chemical Science Co., Ltd	021-58892003	info@qiaochem.com	China	6065	65
YiZheng HaiFan Chemical CO., LTD.	0514-83468749 13852506708	zcw@yzhaifan.com	China	49	58
Creasyn Finechem(Tianjin) Co., Ltd.	022-83946278 13820372920	sales@creasyn.com	China	967	68
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76

Supplier	Advantage
Suzhou Highfine Biotech Co., Ltd	75
Anhui Yongsheng Pharmaceutical Technology Co., Ltd	58
Shandong Libixi Biopharmaceutical Technology Co., Ltd.	58
Shanghai Sunway Pharmaceutical Technology Co., Ltd	57
Suzhou Sino Rare Chemical Co., Ltd.	58
Shanghai Chiyuan Technology Co., Ltd	58
Shanghai Qiao Chemical Science Co., Ltd	65
YiZheng HaiFan Chemical CO., LTD.	58
Creasyn Finechem(Tianjin) Co., Ltd.	68
J & K SCIENTIFIC LTD.	76

View Latest Price from N-(3-Bromopropyl)phthalimide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-24	N-(3-bromopropyl)phthalimide 5460-29-7		25kgs/paper drum	98%	50 tons	YiZheng HaiFan Chemical CO., LTD.
2026-08-25	N-(3-Bromopropyl)phthalimide 5460-29-7	$3.00-9.00		99%		ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-06-08	N-(3-Bromopropyl)phthalimide?? 5460-29-7		1kg	99%	1	Jinan Ruitong Biotech Co., Ltd.

N-(3-bromopropyl)phthalimide
5460-29-7
$0.00
98%
YiZheng HaiFan Chemical CO., LTD.

N-(3-Bromopropyl)phthalimide
5460-29-7
$3.00-9.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

N-(3-Bromopropyl)phthalimide??
5460-29-7
99%
Jinan Ruitong Biotech Co., Ltd.

N-(3-Bromopropyl)phthalimide Spectrum

N-(3-BROMOPROPYL)PHTHALIMIDE(5460-29-7)¹HNMR N-(3-BROMOPROPYL)PHTHALIMIDE(5460-29-7)¹³CNMR N-(3-BROMOPROPYL)PHTHALIMIDE(5460-29-7)IR1 N-(3-BROMOPROPYL)PHTHALIMIDE(5460-29-7)Raman

5460-29-7 (N-(3-Bromopropyl)phthalimide) Related Search:

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N-Methylphthalimide N,N-Diethylformamide N,N-Dimethylbenzamide N-Benzyl-N-propylamine Triethylamine hydrobromide

Diethylamine hydrobromide (3-Bromo-propyl)-dimethyl-amine Dimethylamine hydrobromide N-Benzylformamide N-(3-Bromopropyl)phthalimide

Benzylamine hydrobromide N-Methyl-o-toluamide CHEMBRDG-BB 9070943

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AURORA KA-570 GAMMA-BROMOPROPYLPHTHALIMIDE LABOTEST-BB LT00455358 2-(3-BROMO-PROPYL)-ISOINDOLE-1,3-DIONE 2-(3-BROMOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE AKOS 226-47 TIMTEC-BB SBB003049 2-(3-Bromoprop-1-yl)-1H-isoindole-1,3(2H)-dione, 2-(3-Bromoprop-1-yl)isoindoline-1,3-dione N-(3-Bromoprop-1-yl)phthalimide 1-Phthalimido-3-bromopropane 2-(3-Bromopropyl)-1H-isoindol-1,3(2H)-dione N-(3-BroMopropyl)phthaliMide, 98% 25GR N-(3-BROMOPROPYL)PHTHALIMIDE FOR SYNTHES 2-(BroMopropyl)-1,3-dihydro-1,3-dioxoisoindole N-(3-BroMopropyl)phthaliMide 98% N-(3-Bromopropyl)phthahmide BROMOPROPYLPHTHALIMIDEN3()-- N-(3-Bromopropyl)-Phthalimide~97% N-(3-Bromopropyl)phthalimide,98% 1H-Isoindole-1,3(2H)-dione, 2-(3-bromopropyl)- (3-bromopropyl)phthalimide N-(3-bromopropyl)pthalimide 2-(3-bromopropyl)isoindoline-1,3-dione hydrochloride N-(3-Bromopropyl)phthalimide > Dimethyl 26-bromo terephthalate N-(3-Bromopropyl)phthalimide 2-(3-BroMopropyl)isoindoline-1.3-dione N-(3-Bromopropyl)phthalimide N-(3-Bromopropyl)-1,2-phenylenediamine 5460-29-7 N-Substituted Phthalimides N-Substituted Maleimides, Succinimides & Phthalimides AMINE Cyclic Imides Organic Building Blocks Building Blocks Carbonyl Compounds alkyl bromide N-Substituted Maleimides, Succinimides & Phthalimides N-Substituted Phthalimides Bifunctional CrosslinkersOrganic Building Blocks Carbonyl Compounds Cyclic Imides Linkers Peptide Synthesis