D-DESTHIOBIOTIN
- CAS No.
- 533-48-2
- Chemical Name:
- D-DESTHIOBIOTIN
- Synonyms
- DESTHIOBIOTIN;Dethiobiotin;6-((4R,5S)-5-Methyl-2-oxoiMidazolidin-4-yl)hexanoic acid;ethiobiotin;CAS_533-48-2;D-Dethiobiotin;D-DESTHIOBIOTIN;DL-DESTHIOBIOTIN;Desulfurized biotin;D-desulfurized biotin
- CBNumber:
- CB2259792
- Molecular Formula:
- C10H18N2O3
- Molecular Weight:
- 214.26
- MDL Number:
- MFCD00213804
- MOL File:
- 533-48-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| d-Desthiobiotin ≥98% (TLC) | D1411 | 500mg | $200 |
| d-Desthiobiotin ≥98% (TLC) | D1411 | 1g | $341 |
| D-Desthiobiotin | 71610-M | 1g | $477 |
| D-Desthiobiotin | 30418 | 100mg | $56 |
| D-Desthiobiotin | 30418 | 250mg | $118 |
| Melting point | 156-158° |
|---|---|
| alpha | D21 +10.7° (c = 2) |
| Boiling point | 354.4°C (rough estimate) |
| Density | 1.1404 (rough estimate) |
| refractive index | 1.4550 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| pka | 4.77±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1 |
| InChIKey | AUTOLBMXDDTRRT-UHFFFAOYSA-N |
| SMILES | C1(=O)N[C@@H](C)[C@@H](CCCCCC(O)=O)N1 |
| FDA UNII | 71U5JB52KS |
| UNSPSC Code | 41106500 |
| NACRES | NA.56 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
D-DESTHIOBIOTIN price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D1411 | d-Desthiobiotin ≥98% (TLC) | 533-48-2 | 500mg | $200 | 2025-07-31 | Buy |
| Sigma-Aldrich | D1411 | d-Desthiobiotin ≥98% (TLC) | 533-48-2 | 1g | $341 | 2025-07-31 | Buy |
| Sigma-Aldrich | 71610-M | D-Desthiobiotin | 1g | $477 | 2025-07-31 | Buy | |
| Cayman Chemical | 30418 | D-Desthiobiotin | 533-48-2 | 100mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 30418 | D-Desthiobiotin | 533-48-2 | 250mg | $118 | 2024-03-01 | Buy |
D-DESTHIOBIOTIN Chemical Properties,Uses,Production
Uses
D-Desthiobiotin is an analogue of Biotin (B389040) that binds less tightly to biotin-binding proteins such as Avidin and is easily displaced by Biotin.
Definition
ChEBI: (4R,5S)-dethiobiotin is the (4R,5S)-isomer of dethiobiotin. It is a conjugate acid of a (4R,5S)-dethiobiotin(1-). It is an enantiomer of a (4S,5R)-dethiobiotin.
Biological Activity
Desthiobiotin is a non-sulfur containing biotin derivative th at binds less strongly to biotin-binding proteins and is easily dislocated by biotin.
IC 50
Microbial Metabolite; Human Endogenous Metabolite
Purification Methods
Dissolve desthiobiotin in 0.5% Na2CO3, filter, acidify with HCl to Congo Red, concentrate to a small volume (2-3 mL) to give fine needles, filter it off and recrystallise it twice from H2O, m 157-158o. It also crystallises from 95% EtOH. The methyl ester crystallises from MeOH and sublimes at 100o/high vacuum, m 69-70o, [] D +2.6o (c 2, CHCl3). [Melville et al. Science 98 497 1943, J Am Chem Soc 66 1422 1944, Beilstein 25 III/IV 1543.]
D-DESTHIOBIOTIN Preparation Products And Raw materials
D-DESTHIOBIOTIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Pure Research Chemicals | +86-13564847951 +86-18019592524 | info@purerechem.com | China | 1000 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9258 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18843 | 58 |
View Lastest Price from D-DESTHIOBIOTIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-09 | D-Desthiobiotin
533-48-2
|
US $44.00 / mL | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-11-18 | D-DESTHIOBIOTIN USP/EP/BP
533-48-2
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-06-07 | Dethiobiotin
533-48-2
|
US $0.00 / g | 5g | >95.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-
- D-Desthiobiotin
533-48-2
- US $44.00 / mL
- 99.88%
- TargetMol Chemicals Inc.
-
- D-DESTHIOBIOTIN USP/EP/BP
533-48-2
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Dethiobiotin
533-48-2
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
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