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5-cyclopropylpyridin-3-aMine

CAS No.
1314353-68-8
Chemical Name:
5-cyclopropylpyridin-3-aMine
Synonyms
5-cyclopropylpyridin-3-aMine;5-cyclopropylpyridine-3-amine;3-Amino-5-cyclopropylpyridine;3-Pyridinamine, 5-cyclopropyl-
CBNumber:
CB22631332
Molecular Formula:
C8H10N2
Molecular Weight:
134.18
MDL Number:
MFCD19543987
MOL File:
1314353-68-8.mol
MSDS File:
SDS
Last updated:2026-05-28 00:04:56
Product description Number Pack Size Price
3-Amino-5-cyclopropylpyridine ≥95% OR42287 250mg $58
3-Amino-5-cyclopropylpyridine ≥95% OR42287 1g $177
3-Amino-5-cyclopropylpyridine ≥95% OR42287 5g $879
5-Cyclopropylpyridin-3-amine 95% AS111202 1g $276
5-Cyclopropylpyridin-3-amine 95% AS111202 5g $1043

5-cyclopropylpyridin-3-aMine Properties

Boiling point 308.6±30.0 °C(Predicted)
Density 1.188±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 6.54±0.20(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
HS Code  2933399990

5-cyclopropylpyridin-3-aMine price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR42287 3-Amino-5-cyclopropylpyridine ≥95% 1314353-68-8 250mg $58 2026-06-04 Buy
Apolloscientific OR42287 3-Amino-5-cyclopropylpyridine ≥95% 1314353-68-8 1g $177 2026-06-04 Buy
Apolloscientific OR42287 3-Amino-5-cyclopropylpyridine ≥95% 1314353-68-8 5g $879 2026-06-04 Buy
Activate Scientific AS111202 5-Cyclopropylpyridin-3-amine 95% 1314353-68-8 1g $276 2026-06-04 Buy
Activate Scientific AS111202 5-Cyclopropylpyridin-3-amine 95% 1314353-68-8 5g $1043 2026-06-04 Buy
Product number Packaging Price Buy
OR42287 250mg $58 Buy
OR42287 1g $177 Buy
OR42287 5g $879 Buy
AS111202 1g $276 Buy
AS111202 5g $1043 Buy

5-cyclopropylpyridin-3-aMine Chemical Properties,Uses,Production

Synthesis

3-Amino-5-bromopyridine

13535-01-8

Cyclopropylboronic acid

411235-57-9

5-cyclopropylpyridin-3-aMine

1314353-68-8

General procedure for the synthesis of 5-cyclopropylpyridin-3-amine from 5-bromo-3-aminopyridine and cyclopropylboronic acid: To a solution of 5-bromopyridin-3-amine (4.75 g, 27.45 mmol) in dioxane (45 mL) was added cyclopropylboronic acid (4.75 g, 55.30 mmol), cesium carbonate (Cs2CO3, 28 g, 85.67 mmol) in sequence , tetrakis(triphenylphosphine)palladium (1.66 g, 1.44 mmol), and water (5 mL), and mixed with stirring at room temperature. The reaction mixture was heated to 100 °C with continuous stirring for 15 hours. After the reaction was completed, it was cooled to room temperature and the reaction mixture was diluted with water (200 mL). The mixture was extracted with ethyl acetate (500 mL x 3) and the organic phases were combined. The organic phase was washed with saturated brine and dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed by concentration under reduced pressure and the residue was purified by fast column chromatography using hexane/ethyl acetate (0% to 100% gradient) as eluent to afford 5-cyclopropylpyridin-3-amine as a light brown oil (2.08 g, 56% yield). Mass spectrum (MS): m/z = 135.0 [M + H]+.

References

[1] Patent: WO2017/106607, 2017, A1. Location in patent: Paragraph 00477
[2] Patent: EP2762476, 2014, A1. Location in patent: Paragraph 0174
[3] Patent: US2014/309225, 2014, A1. Location in patent: Paragraph 0700; 0701; 0702; 0703

5-cyclopropylpyridin-3-aMine Preparation Products And Raw materials

5-cyclopropylpyridin-3-aMine Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Yushan Wanfang Biotechnology Co., Ltd.
+86-025-84918180 +86-18014482516 3552541679@qq.com China 995 58
Jilin Chinese Academy of Sciences-yanshen Technology
18143011203 info@chemextension.com China 42052 58
Aladdin Scientific
tp@aladdinsci.com United States 54746 58
Compound Net Biotechnology Inc.
15266686121 sales@compound-net.com China 2913 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7885 64
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4976 55
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518 shyysw007@163.com China 89667 60
Shanghai Rlavie Technology Co., Ltd. 021-67759270 17717059219 sales@rlavie.com China 1850 55

5-cyclopropylpyridin-3-aMine Spectrum

5-cyclopropylpyridin-3-aMine 3-Pyridinamine, 5-cyclopropyl- 3-Amino-5-cyclopropylpyridine 5-cyclopropylpyridine-3-amine 1314353-68-8