3-Amino-5-bromopyridine
- CAS No.
- 13535-01-8
- Chemical Name:
- 3-Amino-5-bromopyridine
- Synonyms
- 5-BROMOPYRIDIN-3-AMINE;5-BROMO-PYRIDIN-3-YLAMINE;CHEMBRDG-BB 4006048;5-brompyridin-3-amin;3-AMino-5-broMopyridi;5-BROMO-3-PYRIDINAMINE;3-Amino-5-Bromopyridie;5-BROMO-3-AMINOPYRIDINE;3-amino-5-bronopyridine;3-AMINO-5-BROMOPYRIDINE
- CBNumber:
- CB8426565
- Molecular Formula:
- C5H5BrN2
- Molecular Weight:
- 173.01
- MDL Number:
- MFCD01646060
- MOL File:
- 13535-01-8.mol
- MSDS File:
- SDS
| Melting point | 65-69 °C |
|---|---|
| Boiling point | 149-150 °C(Press: 12 Torr) |
| Density | 1.710±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 3.81±0.20(Predicted) |
| form | Powder |
| color | White to yellow to brown |
| InChI | InChI=1S/C5H5BrN2/c6-4-1-5(7)3-8-2-4/h1-3H,7H2 |
| InChIKey | MDQXGHBCDCOOSM-UHFFFAOYSA-N |
| SMILES | C1=NC=C(Br)C=C1N |
| CAS DataBase Reference | 13535-01-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi,O | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| RIDADR | Cool, dry,tightly closed | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
3-Amino-5-bromopyridine price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 667129 | 3-Amino-5-bromopyridine 97% | 13535-01-8 | 10g | $108.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | 667129 | 3-Amino-5-bromopyridine 97% | 13535-01-8 | 1g | $39.8 | 2023-06-20 | Buy |
| TRC | A602078 | 3-Amino-5-bromopyridine | 13535-01-8 | 250mg | $55 | 2021-12-16 | Buy |
| TRC | A602078 | 3-Amino-5-bromopyridine | 13535-01-8 | 1g | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA45810 | 3-Amino-5-bromopyridine | 13535-01-8 | 25g | $50 | 2021-12-16 | Buy |
3-Amino-5-bromopyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow Cryst
Uses
3-Amino-5-bromopyridine is used in green preparation of tryptamine salicylic acid compounds as antitumor agent.
Synthesis
28733-43-9
13535-01-8
General procedure for the synthesis of 5-bromo-3-aminopyridine from 5-bromonicotinamide: 1. To a pre-cooled 340 ml aqueous solution containing 31.8 g (0.79 mol) of sodium hydroxide and 40.7 g (0.255 mol) of bromine, 42.0 g (0.209 mol) of commercially available 5-bromonicotinamide was added. 2. The reaction mixture was gradually warmed to room temperature, followed by heating the reaction at 70 °C for 1 hour. 3. Upon completion of the reaction, the resulting brown suspension was allowed to cool to room temperature. 4. The aqueous phase was treated with saturated brine and then extracted three times with a 1:1 solvent mixture of THF and tert-butyl methyl ether. 5. The organic phases were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure. 6. 39.1 g of the dark brown residue obtained from the concentration was purified by fast chromatography (eluent: heptane/ethyl acetate 1:1) to yield 5-bromo-3-aminopyridine as a brown solid (total yield 70.2 g, 70% yield).
References
[1] ChemMedChem, 2014, vol. 9, # 1, p. 217 - 232
[2] Patent: US2006/160857, 2006, A1. Location in patent: Page/Page column 56
[3] Patent: US2006/199960, 2006, A1. Location in patent: Page/Page column 21
[4] Patent: US2006/217387, 2006, A1. Location in patent: Page/Page column 31
[5] Patent: US2003/199511, 2003, A1. Location in patent: Page/Page column 23
3-Amino-5-bromopyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12580 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Hebei Junhua Import and Export Co., LTD | +86-18503288844 | junhua1@hb-junhua.com | China | 957 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
View Lastest Price from 3-Amino-5-bromopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-15 | 3-Amino-5-bromopyridine
13535-01-8
|
US $0.00 / kg | 1kg | 97% | 1000 | Hebei Junhua Import and Export Co., LTD | |
 |
2025-08-08 | 3-Amino-5-bromopyridine
13535-01-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-25 | 3-Amino-5-bromopyridine
13535-01-8
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-Amino-5-bromopyridine
13535-01-8
- US $0.00 / kg
- 97%
- Hebei Junhua Import and Export Co., LTD
-
- 3-Amino-5-bromopyridine
13535-01-8
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 3-Amino-5-bromopyridine
13535-01-8
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
