CATHEPSIN S
- CAS No.
- 71965-46-3
- Chemical Name:
- CATHEPSIN S
- Synonyms
- CTSS;CASS;MGC3886;FLJ50259;CATHEPSIN S;EC 3.4.22.27;Mini Sample Mouse CTSS;Cathepsin S Active human;CATHEPSIN S, BOVINE SPLEEN;Cathepsin S from Human, recombinant
- CBNumber:
- CB2295857
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD02264373
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | -70°C |
|---|---|
| form | aqueous solution |
| color | White to off-white |
| biological source | human |
| Specific Activity | ≥8100pmol/min-μg |
| Major Application | life science and biopharma |
| FDA UNII | ZTW006P2O9 |
| UNSPSC Code | 12352204 |
| NACRES | NA.54 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H360D |
| Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Eye Irrit. 2 Repr. 1B Skin Irrit. 2 |
CATHEPSIN S price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP0292 | Cathepsin S Active human recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE) | 71965-46-3 | 10μG | $722 | 2026-04-30 | Buy |
| Usbiological | 545797 | Cathepsin S PurifiedbyProteinAandpeptideaffinitychromatography. | 200ul | $559 | 2026-06-03 | Buy | |
| Usbiological | 521935 | CTSS Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy | |
| Usbiological | 521935 | CTSS Purifiedbyimmunoaffinitychromatography. | 200ul | $944 | 2026-06-03 | Buy | |
| Usbiological | 309410 | Cathepsin S PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy |
CATHEPSIN S Chemical Properties, Uses, Production
Uses
Active human cathepsin S is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Active human cathepsin S has been used in a study to assess the pathogenesis of Alzheimer′s disease. Active human cathepsin S has also been used in a study to investigate the optimization of selectivity of Azepanone-based inhibitors.
General Description
Human cathepsin S (GenBank Accession No. NM_004079.3), CD33 signal peptide(amino acids 1-16) + cathepsin S (amino acids 17-331), with C-terminal HIS tag, MW = 37 kDa, expressed in FreeStyle 293-F cells.
Biological Activity
Cathepsin S, as a lysosomal protease, facilitates the breakdown of unwanted and damaged proteins in the endo-lysosomal pathway. Moreover, it plays specific roles, such as contributing to major histocompatibility complex (MHC) class II antigen presentation by aiding in the degradation of the invariant chain. Dysregulation of cathepsin S has been associated with various pathological conditions, such as cancer, arthritis, and cardiovascular disease. Cathepsin S is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It is also used as a biomarker for atherosclerosis, diabetes, adiposity, and atherogenesis. Moreover, it acts as a promising target against brain-penetrating and for the treatment of multiple sclerosis and neuropathic pain.
CATHEPSIN S Preparation Products And Raw materials
Raw materials
Preparation Products
CATHEPSIN S Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1592 | 58 |
| Aopeisai Biotechnology (Shanghai) Co., Ltd | 13061929770 | 3004391297@qq.com | China | 1780 | 58 |
| Elabscience | 15608650971 | 1092989564@qq.com | China | 2895 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Supplier | Advantage |
|---|---|
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Biolab Reagents | 58 |
| ACROBiosystems | 58 |
| Aopeisai Biotechnology (Shanghai) Co., Ltd | 58 |
| Elabscience | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 58 |
| shlmai | 58 |
| Creative Enzymes | 58 |
