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Ethyl 1H-indazole-5-carboxylate

CAS No.
192944-51-7
Chemical Name:
Ethyl 1H-indazole-5-carboxylate
Synonyms
Ethyl Indazole-5-carboxylate;ETHYL 1H-INDAZOLE-5-CARBOXYLAT;5-(Ethoxycarbonyl)-1H-indazole;EthylIndazole-5-carboxylate>Ethyl 1H-indazole-5-carboxylate;Ethyl1H-indazole-5-carboxylate,95%;Indazole-5-carboxylic Acid Ethyl Ester;1H-INDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;1H-Indazole-5-carboxylicacid,ethylester(9CI)
CBNumber:
CB2298449
Molecular Formula:
C10H10N2O2
Molecular Weight:
190.2
MDL Number:
MFCD03426220
MOL File:
192944-51-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:37

Ethyl 1H-indazole-5-carboxylate Properties

Melting point 122-124℃
Boiling point 353.9±15.0 °C(Predicted)
Density 1.272±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form powder to crystal
pka 12.81±0.40(Predicted)
color White to Yellow to Orange
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29339900
NFPA 704
1
0 0

Ethyl 1H-indazole-5-carboxylate price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical E1067 Ethyl Indazole-5-carboxylate >98.0%(GC) 192944-51-7 1g $109 2026-04-30 Buy
TCI Chemical E1067 Ethyl Indazole-5-carboxylate >98.0%(GC) 192944-51-7 5g $327 2026-04-30 Buy
Usbiological 275811 Ethyl 1H-Indazole-5-carboxylate Asreported 192944-51-7 250mg $355 2026-06-03 Buy
Usbiological 275811 Ethyl 1H-Indazole-5-carboxylate Asreported 192944-51-7 500mg $489 2026-06-03 Buy
Usbiological 275811 Ethyl 1H-Indazole-5-carboxylate Asreported 192944-51-7 1g $819 2026-06-03 Buy
Product number Packaging Price Buy
E1067 1g $109 Buy
E1067 5g $327 Buy
275811 250mg $355 Buy
275811 500mg $489 Buy
275811 1g $819 Buy

Ethyl 1H-indazole-5-carboxylate Chemical Properties, Uses, Production

Synthesis

ETHYL 1-ACETYL-1H-INDAZOLE-5-CARBOXYLATE

192944-50-6

ETHYL 1H-INDAZOLE-5-CARBOXYLATE

192944-51-7

Ethyl 1-acetyl-1H-indazole-5-carboxylate was used as a raw material, which was dissolved in a mixed solvent consisting of concentrated hydrochloric acid (15 mL), water (15 mL) and ethanol (30 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the pH of the reaction mixture was adjusted to slightly basic with 25% ammonia. Subsequently, the alkalized mixture was extracted with chloroform. The organic phases were combined and purified by hexane crystallization. After completion of crystallization, the resulting crystals were collected by filtration and dried to give the final ethyl 5-indazolecarboxylate (6.45 g, 48% yield) as a light brown powder.

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 1, p. 41 - 58
[2] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0286

Ethyl 1H-indazole-5-carboxylate Preparation Products And Raw materials

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1H-INDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 1H-Indazole-5-carboxylicacid,ethylester(9CI) 5-(Ethoxycarbonyl)-1H-indazole ETHYL 1H-INDAZOLE-5-CARBOXYLAT Ethyl Indazole-5-carboxylate EthylIndazole-5-carboxylate> Ethyl1H-indazole-5-carboxylate,95% Indazole-5-carboxylic Acid Ethyl Ester Ethyl 1H-indazole-5-carboxylate 192944-51-7 CARBOXYLICESTER pharmacetical