ChemicalBook >> CAS DataBase List >>Methyl 1H-indazole-6-carboxylate

Methyl 1H-indazole-6-carboxylate

Methyl 1H-indazole-6-carboxylate structure

CAS No.: 170487-40-8

Chemical Name:: Methyl 1H-indazole-6-carboxylate

Synonyms: 1H-indazole-6-carboxylate;Methyl indazole-6-carboxy...;Methyl indazole-6-carboxylate;Methyl 1H-indazol-6-carboxylate;METHYL 1H-INDAZOLE-6-CARBOXYLATE;1H-Indazole-6-carboxylic acid methyl;INDAZOLE-6-CARBOXYLIC ACID METHYL ESTER;1H-Indazole-6-carboxylic acid methyl ester;6-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER;1H-Indazole-6-carboxylic acid methyl ester

CBNumber:: CB6127192

Molecular Formula:: C9H8N2O2

Molecular Weight:: 176.17

MDL Number:: MFCD07371612

MOL File:: 170487-40-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:56:55

Product description	Number	Pack Size	Price
1H-Indazole-6-carboxylic acid methyl ester Aldrich	SYX00165	1g	$201
Methyl Indazole-6-carboxylate >97.0%(GC)	M2823	1g	$30
Methyl Indazole-6-carboxylate >97.0%(GC)	M2823	5g	$86
METHYL 1H-INDAZOLE-6-CARBOXYLATE 97%	27028	5G	$18
METHYL 1H-INDAZOLE-6-CARBOXYLATE 97%	27028	25G	$47
More product size

Request For Quotation

Methyl 1H-indazole-6-carboxylate Properties

Melting point	142-144℃
Boiling point	345.2±15.0 °C(Predicted)
Density	1.324±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	12.43±0.40(Predicted)
color	White to Light yellow to Light orange
Water Solubility	Soluble in water.
InChI	InChI=1S/C9H8N2O2/c1-13-9(12)6-2-3-7-5-10-11-8(7)4-6/h2-5H,1H3,(H,10,11)
InChIKey	TUSICEWIXLMXEY-UHFFFAOYSA-N
SMILES	N1C2=C(C=CC(C(OC)=O)=C2)C=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

WGK Germany

HS Code

2933998090

NFPA 704

	1
2		0

Methyl 1H-indazole-6-carboxylate price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SYX00165	1H-Indazole-6-carboxylic acid methyl ester Aldrich	170487-40-8	1g	$201	2023-01-07	Buy
TCI Chemical	M2823	Methyl Indazole-6-carboxylate >97.0%(GC)	170487-40-8	1g	$30	2026-04-30	Buy
TCI Chemical	M2823	Methyl Indazole-6-carboxylate >97.0%(GC)	170487-40-8	5g	$86	2026-04-30	Buy
AstaTech	27028	METHYL 1H-INDAZOLE-6-CARBOXYLATE 97%	170487-40-8	5G	$18	2026-04-30	Buy
AstaTech	27028	METHYL 1H-INDAZOLE-6-CARBOXYLATE 97%	170487-40-8	25G	$47	2026-04-30	Buy

Product number	Packaging	Price	Buy
SYX00165	1g	$201	Buy
M2823	1g	$30	Buy
M2823	5g	$86	Buy
27028	5G	$18	Buy
27028	25G	$47	Buy

Methyl 1H-indazole-6-carboxylate Chemical Properties,Uses,Production

Uses

Methyl 1H-indazole-6-carboxylateis used in organic synthesis.

Synthesis

18595-18-1

170487-40-8

Example 1 Preparation of 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(dimethylcarbamoyl)-1H-indazol-3-yl)cyclohex-3-enecarboxylic acid (1A) Step 1: Preparation of methyl 1H-indazole-6-carboxylate (A-2). Methyl 3-amino-4-methylbenzoate (A-1) (5.0 g, 30.2 mmol) was dissolved in acetic acid (140 mL). An aqueous solution of sodium nitrite (2.1 g, 30.2 mmol) was added slowly and dropwise (3.5 mL) to the reaction mixture under cooling in an ice bath. After removing the ice bath, the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, about half of the solvent was removed by evaporation, and the remaining mixture was diluted with water (80 mL) and extracted with ethyl acetate (3 x 30 mL). The organic phases were combined, washed sequentially with water and saturated saline (2×200 mL each), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give the product A-2 (4.4 g, 83% yield). LCMS (ESI): calculated value for C9H8N2O2, [M + H]+: 177, measured value: 177.

References

[1] Patent: WO2008/61109, 2008, A2. Location in patent: Page/Page column 29-30
[2] Patent: WO2014/26328, 2014, A1. Location in patent: Page/Page column 39-40
[3] Patent: WO2014/28597, 2014, A2. Location in patent: Page/Page column 56
[4] Patent: WO2014/26327, 2014, A1. Location in patent: Page/Page column 59
[5] Patent: WO2014/28600, 2014, A2. Location in patent: Page/Page column 50; 51

Methyl 1H-indazole-6-carboxylate synthesis

Synthesis of Methyl 1H-indazole-6-carboxylate from Methyl 3-amino-4-methylbenzoate

Methyl 1H-indazole-6-carboxylate Preparation Products And Raw materials

Raw materials

Benzoic acid, 3-hydrazinyl-4-methyl-, methyl ester Methyl 3-amino-4-methylbenzoate 3-Amino-4-methylbenzoic acid TERT-BUTYL METHYL 1H-INDAZOLE-1,6-DICARBOXYLATE Sodium nitrite

1H-indazole-6-carboxylic acid Methanol 4-Methyl-3-nitrobenzoic acid Ammonium fluoborate Iodomethane

1of2

Preparation Products

methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate Methyl 1-methylindazole-6-carboxylate tert-butyl 6-(hydroxyMethyl)-1H-indazol-1-carboxylate

Methyl 1H-indazole-6-carboxylate Suppliers

Global( 213)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58

Supplier	Advantage
Labnetwork lnc.	58
Accela ChemBio Inc.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58

View Lastest Price from Methyl 1H-indazole-6-carboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	Methyl 1H-indazole-6-carboxylate 170487-40-8	US $1.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-05-26	Methyl 1H-indazole-6-carboxylate 170487-40-8	US $120.00 / kg	1kg	0.99	1000000	Hebei Fengjia New Material Co., Ltd
2025-04-04	Methyl 1H-indazole-6-carboxylate 170487-40-8	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

Methyl 1H-indazole-6-carboxylate
170487-40-8
US $1.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Methyl 1H-indazole-6-carboxylate
170487-40-8
US $120.00 / kg
0.99
Hebei Fengjia New Material Co., Ltd

Methyl 1H-indazole-6-carboxylate
170487-40-8
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Methyl 1H-indazole-6-carboxylate Spectrum

Methyl 1H-indazole-6-carboxylate(170487-40-8)¹HNMR

170487-40-8(Methyl 1H-indazole-6-carboxylate)Related Search:

Methyl 1H-indazole-6-carboxylate 5-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER 1H-indazole-6-carboxylic acid 4-BROMO-6-METHYLCARBOXYLATE-1H-INDAZOLE-3-CARBOXYLIC ACID 4-AMINO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

3-HYDROXY-6-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER 4-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER 4-METHOXY-6-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER ETHYL 1H-INDAZOLE-6-CARBOXYLATE 4-CHLORO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

4-BROMO-3-HYDROXYMETHYL-1H-INDAZOLE-6-CARBOXYLIC ACID METHYL ESTER 3-BROMO-4-NITRO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER 1H-Indazole-3,6-dicarboxylic acid, 6-methyl ester 4-METHOXY-3,6-DICARBOXYLIC ACID-(1H)INDAZOLE 6-METHYL ESTER 1H-INDAZOLE-6-CARBOXYLIC ACID, 4-BROMO-3-FORMYL-, METHYL ESTER

3-CHLORO-4-NITRO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER 4-AMINO-3-IODO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER 4-NITRO-6-INDAZOLECARBOXYLIC ACID METHYL ESTER

1of4

1H-Indazole-6-carboxylic acid Methyl ester 1H-Indazole-6-carboxylic acid methyl ester METHYL 1H-INDAZOLE-6-CARBOXYLATE INDAZOLE-6-CARBOXYLIC ACID METHYL ESTER 6-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER 1H-Indazole-6-carboxylic acid methyl ester Methyl indazole-6-carboxylate Methyl indazole-6-carboxy... 1H-indazole-6-carboxylate 1H-Indazole-6-carboxylic acid methyl ester, 6-(Methoxycarbonyl)-1H-indole 1H-Indazole-6-carboxylic acid Methyl ester 1H-Indazole-6-carboxylic acid methyl 1H-Indazole-6-carboxylic acid, methyl ester (9CI, ACI) Methyl 1H-indazol-6-carboxylate 170487-40-8