ChemicalBook >> CAS DataBase List >>5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione structure

CAS No.: 145915-60-2

Chemical Name:: 5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione

Synonyms: DAPH-7;DAPH 2;CGP 53353;CGP-53353 solid;CGP 53353, 10 mM in DMSO;PKC_βII/EGFR Inhibitor;5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione;PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem;5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE;5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione

CBNumber:: CB2299648

Molecular Formula:: C20H13F2N3O2

Molecular Weight:: 365.33

MDL Number:: MFCD00938569

MOL File:: 145915-60-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:50:37

Request For Quotation

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione Properties

storage temp.	2-8°C
solubility	DMSO: >10mg/mL
form	solid
color	orange
InChI	1S/C20H13F2N3O2/c21-11-1-5-13(6-2-11)23-17-9-15-16(20(27)25-19(15)26)10-18(17)24-14-7-3-12(22)4-8-14/h1-10,23-24H,(H,25,26,27)
InChIKey	RONQPWQYDRPRGG-UHFFFAOYSA-N
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

WGK Germany	3
Storage Class	11 - Combustible Solids

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	539652	CGP-53353 The PKC	145915-60-2	2mg	$272	2024-03-01	Buy
Sigma-Aldrich	C7866	CGP-53353 solid	145915-60-2	5mg	$313	2022-05-15	Buy
Usbiological	254940	CGP 53353 Asreported	145915-60-2	10mg	$531	2026-06-03	Buy
ChemScene	CS-0029281	CGP-53353 98.87%	145915-60-2	5mg	$173	2026-06-04	Buy
ChemScene	CS-0029281	CGP-53353 98.87%	145915-60-2	10mg	$271	2026-06-04	Buy

Product number	Packaging	Price	Buy
539652	2mg	$272	Buy
C7866	5mg	$313	Buy
254940	10mg	$531	Buy
CS-0029281	5mg	$173	Buy
CS-0029281	10mg	$271	Buy

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione Chemical Properties, Uses, Production

Uses

CGP 53353 inhibited tyrosine kinase activity of the EGF-R in five different human transitional cell carcinoma lines.

Definition

ChEBI: 5,6-bis(4-fluoroanilino)isoindole-1,3-dione is a member of phthalimides.

Biological Activity

Selective inhibitor of PKC β II (IC 50 values are 0.41 and 3.8 μ M for PKC β II and PKC β I respectively). Also inhibits prionogenic Sup35 fibrillization (IC 50 ~ 3.4 μ M) and inhibits de novo A β 42 assembly in vitro .

IC 50

PKCβII: 0.41 mM (IC₅₀); PKCβI: 3.8 mM (IC₅₀)

storage

Store at RT

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione Suppliers

Global Suppliers ( 43)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shanghai Rechem science Co., Ltd.	021-31433387 15618786686	sales@rechemscience.com	China	2970	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6288	58
Changzhou Chenhong Biotechnology Co., Ltd.	+86-0519-85788828 +86-13775037613	sales@chemrenpharm.com	China	4058	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Rechem science Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Changzhou Chenhong Biotechnology Co., Ltd.	58
Energy Chemical	58

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione Spectrum

5,6-BIS[(4-FLUOROPHENYL)AMINO]-1H-ISOINDOLE-1,3(2H)-DIONE(145915-60-2)¹HNMR

145915-60-2 (5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione) Related Search:

5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione 4,5-Dianilinophthalimide 4-Fluorodiphenylamine 3,4-Dimethyldiphenylamine Forskolin

Anti-Aging Compound Library

1of2

CGP 53353 5,6-BIS[(4-FLUOROPHENYL)AMINO]-2H-ISOINDOLE-1,3-DIONE 5,6-Bis[(4-fluorophenyl)amino]-2H-isoindole-1,3-dione, DAPH 2 DAPH 2 DAPH-7 PKCβII/EGFR Inhibitor - CAS 145915-60-2 - Calbiochem 1H-Isoindole-1,3(2H)-dione, 5,6-bis[(4-fluorophenyl)amino]- CGP-53353 solid 5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione CGP 53353, 10 mM in DMSO PKC_βII/EGFR Inhibitor 5,6-Bis[(4-fluorophenyl)amino]-1H-isoindole-1,3(2H)-dione 145915-60-2 C20H13F2N3O2 BioChemical Cell Signaling and Neuroscience Cell Biology Protein Kinase C (PKC) Kinase/Phosphatase Biology Serine/Threonine Kinase Inhibitors Protein Kinase