ChemicalBook >> CAS DataBase List >>M2I-1
M2I-1
- CAS No.
- 312271-03-7
- Chemical Name:
- M2I-1
- Synonyms
- M2I-1;M2I1;M2I 1;M2I-1;Mad2 inhibitor-1;M2I-1, 10 mM in DMSO;Mad2 inhibitor-1 (M2I-1);PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2;5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione;4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-
- CBNumber:
- CB23128969
- Molecular Formula:
- C19H24N4O4S
- Molecular Weight:
- 404.48
- MDL Number:
- MFCD00469459
- MOL File:
- 312271-03-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
M2I-1 price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 5mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 10mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 25mg | $253 | 2026-04-30 | Buy |
| Biosynth | MMA27103 | M2I-1 | 312271-03-7 | 10mg | $772.4 | 2026-06-04 | Buy |
M2I-1 Chemical Properties, Uses, Production
Uses
M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1].
Biological Activity
Cell permeable: yes', 'Primary Target
Mad2', 'Reversible: yes
References
[1] Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666. DOI:10.1021/acschembio.5b00121
M2I-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 86)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 989 | 55 |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 645 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2968 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9711 | 58 |
| Medi-tech Bioscientific Co., Ltd. | 0519-83246372 13585352506 | China | 1838 | 58 |
5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
M2I1;M2I 1;M2I-1
M2I-1
Mad2 inhibitor-1 (M2I-1)
Mad2 inhibitor-1
4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-
PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2
M2I-1, 10 mM in DMSO
312271-03-7
API
