| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
- M2I-1
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- $34.00
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2026-07-27
- CAS:312271-03-7
- Purity: 99.02%
- Supply Ability: 10g
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| Product Name: | M2I-1 | | Synonyms: | 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione;M2I1;M2I 1;M2I-1;M2I-1;Mad2 inhibitor-1 (M2I-1);Mad2 inhibitor-1;4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-;PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2;M2I-1, 10 mM in DMSO | | CAS: | 312271-03-7 | | MF: | C19H24N4O4S | | MW: | 404.48 | | EINECS: | | | Product Categories: | API | | Mol File: | 312271-03-7.mol |  |
| | M2I-1 Chemical Properties |
| density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble | | form | A crystalline solid | | pka | 4.79±0.20(Predicted) | | color | Yellow to orange |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | M2I-1 Usage And Synthesis |
| Uses | M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1]. | | Biological Activity | Cell permeable: yes', 'Primary Target
Mad2', 'Reversible: yes | | References | [1] Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666. DOI:10.1021/acschembio.5b00121 |
| | M2I-1 Preparation Products And Raw materials |
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