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(+)-ITD 1

CAS No.
1409968-46-2
Chemical Name:
(+)-ITD 1
Synonyms
(+)-ITD-1;3-Quinolinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-, ethyl ester, (4R)-
CBNumber:
CB23146244
Molecular Formula:
C27H29NO3
Molecular Weight:
415.52
MDL Number:
MOL File:
1409968-46-2.mol
Last updated:2025-04-18 09:51:53

(+)-ITD 1 Properties

Boiling point 569.9±50.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
pka 1.33±0.70(Predicted)

(+)-ITD 1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth JGC96846 ITD-1 1409968-46-2 10mg $1110 2026-06-04 Buy
Biosynth JGC96846 ITD-1 1409968-46-2 25mg $1809.75 2026-06-04 Buy
Biosynth JGC96846 ITD-1 1409968-46-2 50mg $2895.5 2026-06-04 Buy
Axon Medchem Axon2467 (+)-ITD-1 99% 2mg $181.5 2026-05-19 Buy
aablocks AA00A1C4 (+)-ITD 1 99% 1409968-46-2 2mg $267 2026-05-28 Buy
Product number Packaging Price Buy
JGC96846 10mg $1110 Buy
JGC96846 25mg $1809.75 Buy
JGC96846 50mg $2895.5 Buy
Axon2467 2mg $181.5 Buy
AA00A1C4 2mg $267 Buy

(+)-ITD 1 Chemical Properties, Uses, Production

Uses

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs)[1].

References

[1] Willems E, et al., Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52. DOI:10.1016/j.stem.2012.04.025

(+)-ITD 1 Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-ITD 1 Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
(+)-ITD-1 3-Quinolinecarboxylic acid, 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-, ethyl ester, (4R)- 1409968-46-2