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Semaglutide intermediate

Semaglutide intermediate structure

CAS No.: 1118767-15-9

Chemical Name:: Semaglutide intermediate

Synonyms: Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu;Carbaryl Impurity 1;tBuO-Ste-yGlu(OtBu)-;Somalutide side chain;Semaglutide Impurity 17;Semaglutide Impurity 45;tBuO-Ste-E(AEEA-AEEA-OSu)-OtBu;tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu;tBuO-C18-Glu(AEEA-AEEA-OSu)-OtBu;tBuO-C18-γGlu(tBu)-AEEA-AEEA-OSU

CBNumber:: CB23352999

Molecular Formula:: C47H82N4O15

Molecular Weight:: 943.17

MDL Number:: MFCD32661370

MOL File:: 1118767-15-9.mol

MSDS File:: SDS

Last updated:2026-03-18 11:52:23

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Semaglutide intermediate Properties

Density	1.15±0.1 g/cm3(Predicted)
pka	14.18±0.46(Predicted)
InChIKey	ZYJILBKLUVJVKQ-QNGWXLTQSA-N
SMILES	C(ON1C(=O)CCC1=O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

Semaglutide intermediate Chemical Properties,Uses,Production

Description

Semaglutide intermediates play a crucial role in the synthesis and development of Semaglutide, a potent GLP-1 receptor agonist.

Uses

Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes.

Synthesis

Somalutide side chain is synthesized from tetradecanedioic acid by condensation, reduction, ring-opening and Boc monoprotection of first synthesizing the intermediate mono-tert-butyl octadecanedioate, and then by further condensation reaction of the intermediate.

Semaglutide intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

Semaglutide intermediate Suppliers

Global( 121)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 +8617350879715	changaiwei@sinopeg.com	China	1125	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Adachibio Inc.	+81-8027837258; +8108027837258	sales@adachibio.com	Japan	992	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
Tianjin Zhongxin Chemtech Co., Ltd.	86-22-66880623 +8618622897568	sales@tjzxchem.com	China	572	58
Chengdu Pukang Biotechnology Co., Ltd	028-82550498	export@pu-kang.com	CHINA	210	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58

Supplier	Advantage
Wuhan Topule Biopharmaceutical Co., Ltd	58
BOC Sciences	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
Henan Fengda Chemical Co., Ltd	58
Adachibio Inc.	58
Henan Tianfu Chemical Co.,Ltd.	55
Tianjin Zhongxin Chemtech Co., Ltd.	58
Chengdu Pukang Biotechnology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58

View Lastest Price from Semaglutide intermediate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-05	tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9	US $0.00-0.00 / g	1g	98%	1g/bottle , 10g/bottle, 100g/bottle	XIAMEN SINOPEG BIOTECH CO., LTD.
2025-12-01	Semaglutide intermediate 1118767-15-9	US $0.00 / KG	1KG	98%	1000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	Semaglutide intermediate 1118767-15-9	US $2.00-0.50 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu
1118767-15-9
US $0.00-0.00 / g
98%
XIAMEN SINOPEG BIOTECH CO., LTD.

Semaglutide intermediate
1118767-15-9
US $0.00 / KG
98%
Shaanxi Dideu New Materials Co. Ltd

Semaglutide intermediate
1118767-15-9
US $2.00-0.50 / KG
99%
Henan Fengda Chemical Co., Ltd

1118767-15-9(Semaglutide intermediate)Related Search:

Semaglutide tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu OCTADECANEDIOIC ACID Boc-His(Trt)-Aib-OH 18-(tert-Butoxy)-18-oxooctadecanoic Acid

Boc-NH-PEG2-CH2COOH Fmoc-8-amino-3,6-dioxaoctanoic acid

1of2

Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu 3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester, (22S)- tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu 17-((S)-1-tert-Butoxycarbonyl-3-{2-[2-({2-[2-(2,5-dioxopyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]-ethylcarbamoyl}propylcarbamoyl)heptadecanoic acid tert-butyl ester 21,39-di-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) (S)-9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate tBuO-C18-Glu(AEEA-AEEA-OSu)-OtBu tBuO-Ste-γGlu(OtBu)-AEEA-AEEA-OSu tBuO-Ste-rGlu(OtBu)-AEEA-AEEA-OSu tert-butyl 18-[[(2S)-5-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-[(2-methylpropan-2-yl)oxy]-1,5-dioxopentan-2-yl]amino]-18-oxooctadecanoate tBuO-Ste-yGlu(OtBu)- tBuO-Ste-E(AEEA-AEEA-OSu)-OtBu tBuO-C18-y-Glu(AEEA-AEEA-OSu)-OtBu Somalutide side chain tBuO-C18-γGlu(tBu)-AEEA-AEEA-OSU Octa(OtBu)-Glu(AEEA-AEEA-OSu)-OtBu Carbaryl Impurity 1 Semaglutide Impurity 17 Semaglutide Impurity 45 OtBu-C18-Glu(OtBu)-AEEA-AEEA-NHS、tBuO-Ste-Glu(OtBu)-AEEA-AEEA-OSU tBuO-C18-γ-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9 118767-16-0 C47H82N4O15