Semaglutide intermediate manufacturers
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| | Semaglutide intermediate Basic information |
| Product Name: | Semaglutide intermediate | | Synonyms: | Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu;3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester, (22S)-;17-((S)-1-tert-Butoxycarbonyl-3-{2-[2-({2-[2-(2,5-dioxopyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]-ethylcarbamoyl}propylcarbamoyl)heptadecanoic acid tert-butyl ester;tBuO-Ste-γGlu(OtBu)-AEEA-AEEA-OSu;tert-butyl 18-[[(2S)-5-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-[(2-methylpropan-2-yl)oxy]-1,5-dioxopentan-2-yl]amino]-18-oxooctadecanoate;tBuO-Ste-yGlu(OtBu)-;tBuO-Ste-E(AEEA-AEEA-OSu)-OtBu;tBuO-C18-y-Glu(AEEA-AEEA-OSu)-OtBu | | CAS: | 1118767-15-9 | | MF: | C47H82N4O15 | | MW: | 943.17 | | EINECS: | | | Product Categories: | | | Mol File: | 1118767-15-9.mol |  |
| | Semaglutide intermediate Chemical Properties |
| density | 1.15±0.1 g/cm3(Predicted) | | pka | 14.18±0.46(Predicted) | | InChIKey | ZYJILBKLUVJVKQ-QNGWXLTQSA-N | | SMILES | C(ON1C(=O)CCC1=O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O |
| | Semaglutide intermediate Usage And Synthesis |
| Description | Semaglutide intermediates play a crucial role in the synthesis and development of Semaglutide, a potent GLP-1 receptor agonist.
| | Uses |
Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes.
| | Synthesis | Somalutide side chain is synthesized from tetradecanedioic acid by condensation, reduction, ring-opening and Boc monoprotection of first synthesizing the intermediate mono-tert-butyl octadecanedioate, and then by further condensation reaction of the intermediate. |
| | Semaglutide intermediate Preparation Products And Raw materials |
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