Thiodigalactoside
- CAS No.
- 51555-87-4
- Chemical Name:
- Thiodigalactoside
- Synonyms
- TDG;Thiodigalactoside;Thiodigalactoside - Bio-X ?;Galactosyl 1-thiogalactoside;Thiodigalactoside, 10 mM in DMSO;D-Galactopyranosyl-b-D-thiogalactopyranoside;d-galactopyranosyl-β-d-thiogalactopyranoside;D-GALACTOPYRANOSYL BETA-D-THIOGALACTOPYRANOSIDE;D-Galactopyranosyl-β-D-thiogalactopyranoside ,98%;β-D-Galactopyranoside, β-D-galactopyranosyl 1-thio-
- CBNumber:
- CB2340922
- Molecular Formula:
- C12H22O10S
- Molecular Weight:
- 358.36
- MDL Number:
- MFCD00057491
- MOL File:
- 51555-87-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >225°C (dec.) |
|---|---|
| Boiling point | 712.565±60.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.779±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly) |
| form | Solid |
| pka | 12.629±0.70(predicted) |
| color | White |
| Water Solubility | H2O: 2mg/mL, clear |
| InChI | InChI=1/C12H22O10S/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12/h3-20H,1-2H2/t3-,4-,5+,6+,7+,8+,9-,10-,11+,12/s3 |
| InChIKey | SYKYBMOFPMXDRQ-YSLNCGCNNA-N |
| SMILES | C1([C@H](O)[C@H]([C@@H](O)[C@@H](CO)O1)O)S[C@H]1[C@H](O)[C@H]([C@@H](O)[C@@H](CO)O1)O |&1:1,3,4,6,12,13,15,16,18,r| |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| HS Code | 29389090 |
| Storage Class | 11 - Combustible Solids |
Thiodigalactoside price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17154 | Thiodigalactoside ≥98% | 51555-87-4 | 25mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 17154 | Thiodigalactoside ≥98% | 51555-87-4 | 50mg | $93 | 2026-04-30 | Buy |
| Cayman Chemical | 17154 | Thiodigalactoside ≥98% | 51555-87-4 | 100mg | $132 | 2026-04-30 | Buy |
| Cayman Chemical | 17154 | Thiodigalactoside ≥98% | 51555-87-4 | 250mg | $190 | 2026-04-30 | Buy |
| Usbiological | 528981 | TDG Purifiedbyimmunoaffinitychromatography. | 100ul | $736 | 2026-06-03 | Buy |
Thiodigalactoside Chemical Properties,Uses,Production
Description
Galectins are a family of glycan-binding lectins with diverse regulatory roles in physiological processes. They have significant roles in inflammation and cancer. Thiodigalactoside is a diglycan that binds galectins-1, -3, -8, and -9 with Kd values between 24 and 78 μM. It is used to investigate the roles of these galectins in cell signaling and carcinogenesis.
Chemical Properties
White to off-white crystalline powder
Uses
Thiogdigalactosideis an inhibitor of galectin 1 which has an essential role in high-fat diet induced obesity development.
References
[1] ALI HASAN EBRAHIM. Galectins in cancer: carcinogenesis, diagnosis and therapy.[J]. Annals of translational medicine, 2014, 2 9: 88. DOI: 10.3978/j.issn.2305-5839.2014.09.12
[2] NANDOR GABOR THAN. Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia.[J]. Journal of Pathology and Translational Medicine, 2015, 49 3: 181-208. DOI: 10.4132/jptm.2015.02.25
[3] BADER A. SALAMEH . 1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors[J]. Bioorganic & Medicinal Chemistry, 2010, 18 14: Pages 5367-5378. DOI: 10.1016/j.bmc.2010.05.040
[4] HILDE VAN HATTUM. Tuning the Preference of Thiodigalactoside- and Lactosamine-Based Ligands to Galectin-3 over Galectin-1[J]. Journal of Medicinal Chemistry, 2013, 56 3: 1350-1354. DOI: 10.1021/jm301677r
[5] KOICHI ITO. Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress[J]. Angiogenesis, 2011, 14 3: 293-307. DOI: 10.1007/s10456-011-9213-5
[6] PEIWEN KUO. Galectin-1 mediates radiation-related lymphopenia and attenuates NSCLC radiation response.[J]. Clinical Cancer Research, 2014, 20 21: 5558-5569. DOI: 10.1158/1078-0432.ccr-14-1138
[7] R MUKHERJEE. Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats[J]. International Journal of Obesity, 2015, 39 9: 1349-1358. DOI: 10.1038/ijo.2015.74
Thiodigalactoside Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Z-trans Biochemistry Technology (Suzhou) Co.,Ltd | 0512-66317708 13372112871 | huijuan@zitrans.cn | China | 2260 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
View Lastest Price from Thiodigalactoside manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Thiodigalactoside
51555-87-4
|
10G | 98%min | 30kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-15 | Thiodigalactoside
51555-87-4
|
$34.00-52.00 | 99.90% | 10g | TargetMol Chemicals Inc. |
-
- Thiodigalactoside
51555-87-4
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Thiodigalactoside
51555-87-4
- $34.00-52.00
- 99.90%
- TargetMol Chemicals Inc.
