1,8-Naphthyridine
- CAS No.
- 254-60-4
- Chemical Name:
- 1,8-Naphthyridine
- Synonyms
- 1, 8 - nalidixic;1,8-NAPHTHYRIDINE;1,8-Pyridopyridine;1,8-Diazanapthalene;1,8-Naphthyridine>1,8-DIAZANAPHTHALENE;PYRIDO[2,3-B]PYRIDINE;1,8-NAPHTHYRIDINE 98+%;1,8-Diazanaphthalene 98%;1,8-Naphthyridine(6CI,7CI,8CI,9CI)
- CBNumber:
- CB2352000
- Molecular Formula:
- C8H6N2
- Molecular Weight:
- 130.15
- MDL Number:
- MFCD00059751
- MOL File:
- 254-60-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 99.8-99.9°C |
|---|---|
| Boiling point | 248.9±13.0 °C(Predicted) |
| Density | 1.183±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.39 |
| form | powder to crystal |
| pka | 3.55±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C8H6N2/c1-3-7-4-2-6-10-8(7)9-5-1/h1-6H |
| InChIKey | FLBAYUMRQUHISI-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CN=2)C=CC=1 |
| CAS DataBase Reference | 254-60-4(CAS DataBase Reference) |
| FDA UNII | 043R04VL4M |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2902900000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 |
|||||||||
| NFPA 704 |
|
1,8-Naphthyridine price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS021459 | 1,8-Naphthyridine | 254-60-4 | 10 mg | $77.9 | 2026-04-30 | Buy |
| TCI Chemical | N0464 | 1,8-Naphthyridine >98.0%(GC) | 254-60-4 | 1g | $124 | 2026-04-30 | Buy |
| TCI Chemical | N0464 | 1,8-Naphthyridine >98.0%(GC) | 254-60-4 | 100mg | $21 | 2026-04-30 | Buy |
| Activate Scientific | AS40063 | 1,8-Diazanapthalene 95% | 254-60-4 | 1g | $31 | 2026-06-04 | Buy |
| Apolloscientific | OR45139 | 1,8-Diazanaphthalene 98% | 254-60-4 | 1g | $66 | 2026-06-04 | Buy |
1,8-Naphthyridine Chemical Properties, Uses, Production
Description
1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.
Uses
1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.
Definition
ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8.
Purification Methods
Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]
1,8-Naphthyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Weifang Yuda Pharmaceutical Technology Co., Ltd. | 17663603912 | 2710256076@qq.com | China | 119 | 56 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 996 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from 1,8-Naphthyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 1,8-NAPHTHYRIDINE
254-60-4
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-15 | 1,8-NAPHTHYRIDINE
254-60-4
|
$1.00 | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-
- 1,8-NAPHTHYRIDINE
254-60-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 1,8-NAPHTHYRIDINE
254-60-4
- $1.00
- 99%
- Career Henan Chemical Co
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