MSOP
- CAS No.
- 66515-29-5
- Chemical Name:
- MSOP
- Synonyms
- MSOP;2-Methyl-O- phosphonoserine;Serine, 2-methyl-O-phosphono-;(RS)-α-Methylserine-O-phosphate;(R,S)-a-Methylserine-O-phosphate;(RS)-ALPHA-METHYLSERINE-O-PHOSPHATE;MSOP, group III metabotropic glutamate receptor antagonist
- CBNumber:
- CB2407711
- Molecular Formula:
- C4H10NO6P
- Molecular Weight:
- 199.1
- MDL Number:
- MFCD00673768
- MOL File:
- 66515-29-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
MSOP price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 456675 | MSOP | 66515-29-5 | 10mg | $439 | 2026-06-03 | Buy |
| Usbiological | 456675 | MSOP | 66515-29-5 | 25mg | $701 | 2026-06-03 | Buy |
| Usbiological | 255915 | MSOP Asreported | 66515-29-5 | 10mg | $466 | 2026-06-03 | Buy |
| Usbiological | 255915 | MSOP Asreported | 66515-29-5 | 50mg | $1253 | 2026-06-03 | Buy |
| Biosynth | RCA51529 | MSOP | 66515-29-5 | 25mg | $957 | 2026-06-05 | Buy |
MSOP Chemical Properties, Uses, Production
Uses
MSOP is a selective antagonist of group III mGlu receptors.
Biological Activity
MSOP is a selective group III metabotropic glutamate receptor antagonist. Displays an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. Has no activity on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons.
in vivo
It is found that TBOA-induced antinociceptive effects are significantly blocked by intrathecal co-administration of MSOP (second phase of formalin model: F3,16=30.96, P<0.001; CFA model: F3,16=30.77, P<0.001). As expected, intrathecal TBOA (10 μg) reduces the number of formalin-induced flinches and shakes by 47% of the value in the saline-treated group in the second phase (P<0.001) and blocked the CFA-induced decrease in ipsilateral paw withdrawal latency by 60% of the value in the saline-treated group (P=0.01). The number of formalin-induced flinches in the second phase in the group treated with MSOP and TBOA is increased by 56% (P=0.04) of the value in the TBOA-treated group. CFA-induced paw withdrawal latency in the group treated with MSOP and TBOA is decreased by 86% (P=0.03) of the value in the TBOA-treated group[2].
storage
Store at RT
MSOP Preparation Products And Raw materials
Raw materials
Preparation Products
MSOP Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10233 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
