4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
- CAS No.
- 320-43-4
- Chemical Name:
- 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
- Synonyms
- 4-Chloro-2-(trifluoromethyl)benzald;2-TRIFLUOROMETHYL-4-CHLOROBENZALDEHYDE;4-Chloro-2-fluoro-7-methoxyacetophenone;2-(Trifluoromthyl)-4-Chlorobenzaldehyde;4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE;Benzaldehyde, 4-chloro-2-(trifluoromethyl)-;4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE, 97%+
- CBNumber:
- CB2418832
- Molecular Formula:
- C8H4ClF3O
- Molecular Weight:
- 208.57
- MDL Number:
- MFCD03092987
- MOL File:
- 320-43-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | PC0558 | 5g | $21 |
| 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | PC0558 | 25g | $79 |
| 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | PC0558 | 100g | $252 |
| 4-Chloro-2-(trifluoromethyl)benzaldehyde 98% | AS38233 | 1g | $26 |
| 4-Chloro-2-(trifluoromethyl)benzaldehyde 98% | AS38233 | 5g | $49 |
| More product size | |||
| Boiling point | 218.5±40.0 °C(Predicted) |
|---|---|
| Density | 1.423±0.06 g/cm3(Predicted) |
| refractive index | 1.4960 |
| storage temp. | 2-8°C, stored under nitrogen |
| form | liquid |
| color | Clear, colourless |
| Sensitive | Air Sensitive |
| CAS DataBase Reference | 320-43-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-36-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2913000090 | |||||||||
| NFPA 704 |
|
4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC0558 | 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | 320-43-4 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC0558 | 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | 320-43-4 | 25g | $79 | 2026-06-04 | Buy |
| Apolloscientific | PC0558 | 4-Chloro-2-(trifluoromethyl)benzaldehyde ≥95% | 320-43-4 | 100g | $252 | 2026-06-04 | Buy |
| Activate Scientific | AS38233 | 4-Chloro-2-(trifluoromethyl)benzaldehyde 98% | 320-43-4 | 1g | $26 | 2026-06-04 | Buy |
| Activate Scientific | AS38233 | 4-Chloro-2-(trifluoromethyl)benzaldehyde 98% | 320-43-4 | 5g | $49 | 2026-06-04 | Buy |
4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE Chemical Properties,Uses,Production
Synthesis
320-41-2
320-43-4
The general procedure for the synthesis of 4-chloro-2-trifluoromethylbenzaldehyde using 2-trifluoromethyl-4-chlorobenzonitrile as a starting material was as follows: 2-trifluoromethyl-4-chlorobenzonitrile (appropriate amount) was added to a mixed solution of formic acid (96%, 15 mL) and water (3 mL). Nickel-aluminum alloy (1260 mg) was then added. The reaction mixture was heated and reacted at 100 °C overnight. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and filtered through diatomaceous earth to remove solid impurities. The filtrate was sequentially extracted with 1N sodium hydroxide solution and saturated aqueous sodium chloride solution. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give 4-chloro-2-trifluoromethylbenzaldehyde (555 mg, 87% yield). The product was characterized by 1HNMR (400 MHz, MeOH-d4): δ 10.29 (m, 1H), 8.10 (d, 1H, J = 8.4 Hz), 7.91 (d, 1H, J = 1.6 Hz), 7.85 (dd, 1H, J = 8.4,1.6 Hz).
References
[1] Patent: WO2006/44454, 2006, A1. Location in patent: Page/Page column 63
4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2971 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
View Lastest Price from 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
320-43-4
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
![]() |
2020-02-01 | 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
320-43-4
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-

- 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
320-43-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 4-CHLORO-2-(TRIFLUOROMETHYL)BENZALDEHYDE
320-43-4
- $3.00
- 98%
- Career Henan Chemical Co
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