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Boc-L-Histidine(Tosyl)

CAS No.
35899-43-5
Chemical Name:
Boc-L-Histidine(Tosyl)
Synonyms
BOC-HIS(TOS)-OH;Nα-(tert-Butoxycarbonyl)-τ-(p-toluenesulfonyl)-L-histidine;BOC-HIS(TOS);BOC-L-HIS(TOS);BOC-L-HIS(TOS)-OH;Boc-His(1-Tos)-OH;Boc-His(t-Tos)-OH;H-Octyl-Gly-OH(S);BOC-HIS(TOS)-OH IPA;Boc-His(tau-Tos)-OH
CBNumber:
CB2422161
Molecular Formula:
C18H23N3O6S
Molecular Weight:
409.46
MDL Number:
MFCD00065967
MOL File:
35899-43-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:28:25

Boc-L-Histidine(Tosyl) Properties

Melting point ~125 °C (dec.)
Density 1.19
storage temp. -20°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.50±0.10(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]20/D +16±1°, c = 1% in methanol
BRN 769957
Major Application peptide synthesis
InChI 1S/C18H23N3O6S/c1-12-5-7-14(8-6-12)28(25,26)21-10-13(19-11-21)9-15(16(22)23)20-17(24)27-18(2,3)4/h5-8,10-11,15H,9H2,1-4H3,(H,20,24)(H,22,23)/t15-/m0/s1
InChIKey DCLJSEPKYJSEHW-HNNXBMFYSA-N
SMILES Cc1ccc(cc1)S(=O)(=O)n2cnc(C[C@H](NC(=O)OC(C)(C)C)C(O)=O)c2
CAS DataBase Reference 35899-43-5(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
HS Code  29350090
Storage Class 13 - Non Combustible Solids
NFPA 704
1
0 0

Boc-L-Histidine(Tosyl) price More Price(85)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.53041 Boc-His(Tos)-OH Novabiochem? 35899-43-5 100g $386 2026-04-30 Buy
Sigma-Aldrich 15559 Boc-His(Tos)-OH ≥98.0% (TLC) 35899-43-5 5g $27.1 2023-06-20 Buy
Sigma-Aldrich 8.53041 Boc-His(Tos)-OH Novabiochem? 35899-43-5 25g $99.4 2023-01-07 Buy
TCI Chemical B2066 Nalpha-(tert-Butoxycarbonyl)-tele-(p-toluenesulfonyl)-L-histidine >98.0%(T) 35899-43-5 5g $81 2024-03-01 Buy
TCI Chemical B2066 Nalpha-(tert-Butoxycarbonyl)-tele-(p-toluenesulfonyl)-L-histidine >98.0%(T) 35899-43-5 25g $293 2024-03-01 Buy
Product number Packaging Price Buy
8.53041 100g $386 Buy
15559 5g $27.1 Buy
8.53041 25g $99.4 Buy
B2066 5g $81 Buy
B2066 25g $293 Buy

Boc-L-Histidine(Tosyl) Chemical Properties,Uses,Production

Chemical Properties

White to light yellow crystal powde

Uses

Boc-L-His(Tos)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

98-59-9
17791-52-5
35899-43-5
Synthesis of Boc-L-Histidine(Tosyl) from Tosyl chloride and N-Boc-L-Histidine

Boc-L-Histidine(Tosyl) Preparation Products And Raw materials

Global( 257)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Sichuan Guanghan Bio-Tech Co., Ltd +86-28-86127071 info@sino-produce.com China 400 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62

View Lastest Price from Boc-L-Histidine(Tosyl) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-L-Histidine(Tosyl) pictures 2019-07-06 Boc-L-Histidine(Tosyl)
35899-43-5
$1.00 1KG 99% 20kg Career Henan Chemical Co
Boc-L-Histidine(Tosyl) pictures 2019-07-06 Boc-L-Histidine(Tosyl)
35899-43-5
$7.00 1KG 99% 1000KG Career Henan Chemical Co

Boc-L-Histidine(Tosyl) Spectrum

BOC-N-IM-4-TOLUENESYLFONYL-L-HISTIDINE BOC-L-HISTIDINE(TOSYL) BOC-L-HIS(TOS) BOC-L-HIS(TOS)-OH BOC-HIS(TOS) BOC-HISTIDINE(TOS)-OH BOC-HIS(TOS)-OH IPA NALPHA-BOC-TELE-TOSYL-L-HISTIDINE N-ALPHA-BOC-NIM-TOSYL-L-HISTIDINE ISOPROPYL ALCOHOL N-ALPHA-BOC-N(IM)-TOSYL-L-HISTIDINE N-ALPHA-TERT-BUTYLOXYCARBONYL-N-IM-TOSYL-L-HISTIDINE N ALPHA-T-BUTOXYCARBONYL-N(IM)-TOSYL-L-HISTIDINE N-ALPHA-T-BUTOXYCARBONYL-N-TAU-TOSYL-L-HISTIDINE N-ALPHA-T-BUTYLOXYCARBONYL-N-TAU-TOSYL-L-HISTIDINE NALPHA-TERT-BUTOXYCARBONYL-N(IM)-TOSYL-L-HISTIDINE N-(ALPHA)-(TERT-BUTOXYCARBONYL)-TAU-(P-TOLUENESULFONYL)-L-HISTIDINE NALPHA-(TERT-BUTOXYCARBONYL)-TELE-(P-TOLUENESULFONYL)-L-HISTIDINE NALPHA-(TERT-BUTOXYCARBONYL)-T-(P-TOLUENESULFONYL)-L-HISTIDINE N-ALPHA-T-BOC-IM-TOSYL-L-HIS N-ALPHA-T-BOC-N-IM-TOSYL-L-HISTIDINE Nα-Boc-N(im)-tosyl-L-histidine Butoxycarbonyltoluenosulfonylhistidine N^(alpha)-(tert-Butoxycarbonyl)-tau-(p-toluenosulfonyl)-L-histidine N-T-boc-im-tosyl-L-histidine free acid N-tert-Butoxycarbonyl-N-imidazole-(4-toluenesulfonyl)-L-histidine N-alpha-t-Butyloxycarbonyl-N-im-t-tosyl-L-histidine Boc-His(Tos)-OH >=98.0% (TLC) (R)-L-(+)-Boc-his(tos)-OH Boc-His(1-Tos)-OH Boc-His(tau-Tos)-OH nα-boc-n(im)-tosyl-l-histidine N-ALPHA-T-BUTYLOXYCARBONYL-N-IM-TOSYL-L-HISTIDINE NALPHA-tert-Butoxycarbonyl-N-imidazole-(4-toluenesulfonyl)-L-histidine Nα-Boc-Nim-4-toluenesylfonyl-L-histidine≥ 98% (HPLC) N-(tert-butoxycarbonyl)-im-tosyl-L-histidine (S)-2-(tert-butoxycarbonylamino)-3-(1-tosyl-1H-imidazol-4-yl)propanoic acid Boc-L-Histidine(Tosy L-Histidine, N-[(1,1-diMethylethoxy)carbonyl]-1-[(4-Methylphenyl)sulfonyl]- Nalpha-Boc-tele-tosyl-L-histidine Boc-His(Tos)-OH Boc-His(t-Tos)-OH N^a-Boc-1-toluenesulfonyl-L-histidine, 98% 2-{[(tert-butoxy)carbonyl]aMino}-3-{1-[(4-Methylbenzene)sulfonyl]-1H-iMidazol-4-yl}propanoic acid N-Boc-1-(p-toluenesulfonyl)-L-histidine, 98% Nα-Boc-τ-tosyl-L-histidine Nα-Boc-τ-tosyl-L-histidine (Tert-Butoxy)Carbonyl His(Tos)-OH (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[1-(4-methylbenzenesulfonyl)-1H-imidazol-4-yl]propanoic acid 3-[1-(4-methylphenyl)sulfonyl-4-imidazolyl]-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid H-Octyl-Gly-OH(S) Nα-(tert-Butoxycarbonyl)-τ-(p-toluenesulfonyl)-L-histidine > Boc-L-Histidine(Tosyl) USP/EP/BP Nα-Boc-Nim-4-toluenesylfonyl-L-histidine (2S)-3-[1-(4-methylphenyl)sulfonylimidazol-4-yl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid N-[(1,1-Dimethylethoxy)carbonyl]-1-[(4-methylphenyl)sulfonyl]-L-histidine BOC-HIS(TOS)-OH Nα-(tert-Butoxycarbonyl)-τ-(p-toluenesulfonyl)-L-histidine 35899-43-5 72246-24-8