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3-Amino-4-chlorobenzotrifluoride

3-Amino-4-chlorobenzotrifluoride structure

CAS No.: 121-50-6

Chemical Name:: 3-Amino-4-chlorobenzotrifluoride

Synonyms: 2-CHLORO-5-(TRIFLUOROMETHYL)ANILINE;Fast Orange RD Salt;Fast Orange Salt RD;6-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUIDINE;usafma-13;C.I. 37050;USAF ma-13;orangesaltnrd;2-Chloro-5-(tr;Orange Salt NRD

CBNumber:: CB2430564

Molecular Formula:: C7H5ClF3N

Molecular Weight:: 195.57

MDL Number:: MFCD00007673

MOL File:: 121-50-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:28:22

Product description	Number	Pack Size	Price
3-Amino-4-chlorobenzotrifluoride for synthesis	8.41772	50mL	$120
3-Amino-4-chlorobenzotrifluoride	8.41772	8417720050	$104
3-Amino-4-chlorobenzotrifluoride >98.0%(GC)	A0948	25g	$47
3-Amino-4-chlorobenzotrifluoride >98.0%(GC)	A0948	500g	$365
3-Amino-4-chlorobenzotrifluoride	140023	1.00g	$101
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3-Amino-4-chlorobenzotrifluoride Properties

Melting point	10 °C
Boiling point	82-83 °C (9 mmHg)
Density	1.428 g/mL at 25 °C(lit.)
vapor pressure	0.15 hPa
refractive index	n20/D 1.499(lit.)
Flash point	75 °C
storage temp.	Store below +30°C.
solubility	11g/l
pka	1.43±0.10(Predicted)
form	clear liquid
Colour Index	37050
color	Colorless to Yellow to Green
Specific Gravity	1.428
Water Solubility	11 g/L (60 ºC)
BRN	879910
InChI	1S/C7H5ClF3N/c8-5-2-1-4(3-6(5)12)7(9,10)11/h1-3H,12H2
InChIKey	VKTTYIXIDXWHKW-UHFFFAOYSA-N
SMILES	FC(F)(F)c1cc(c(cc1)Cl)N
CAS DataBase Reference	121-50-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	7XBP8297PJ
NIST Chemistry Reference	Benzenamine, 2-chloro-5-(trifluoromethyl)-(121-50-6)
EPA Substance Registry System	Benzenamine, 2-chloro-5-(trifluoromethyl)- (121-50-6)
UNSPSC Code	12352116
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H411

Precautionary statements

P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338

Hazard Codes

Xn,Xi,N

Risk Statements

20/21/22-51/53-36/37/38

Safety Statements

36/37-60-57-36/37/39-26-36

RIDADR

UN 2810 6.1/PG 3

WGK Germany

RTECS

XU5775000

Autoignition Temperature

≥560°C

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

III

HS Code

29214300

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2

REACH Registrations

Active

NFPA 704

	1
2		0

3-Amino-4-chlorobenzotrifluoride price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.41772	3-Amino-4-chlorobenzotrifluoride for synthesis	121-50-6	50mL	$120	2026-04-30	Buy
Sigma-Aldrich	8.41772	3-Amino-4-chlorobenzotrifluoride	121-50-6	8417720050	$104	2021-12-16	Buy
TCI Chemical	A0948	3-Amino-4-chlorobenzotrifluoride >98.0%(GC)	121-50-6	25g	$47	2026-04-30	Buy
TCI Chemical	A0948	3-Amino-4-chlorobenzotrifluoride >98.0%(GC)	121-50-6	500g	$365	2026-04-30	Buy
Matrix Scientific	140023	3-Amino-4-chlorobenzotrifluoride	121-50-6	1.00g	$101	2026-05-18	Buy

Product number	Packaging	Price	Buy
8.41772	50mL	$120	Buy
8.41772	8417720050	$104	Buy
A0948	25g	$47	Buy
A0948	500g	$365	Buy
140023	1.00g	$101	Buy

3-Amino-4-chlorobenzotrifluoride Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLORLESS TO LIGHT YELLOW LIQUID

Uses

2-Chloro-5-trifluoromethylaniline

Synthesis

328-84-7

39885-50-2

121-50-6

Example 1: N-methylpyrrolidone (1050 mL) was added to an autoclave with 102 g of anhydrous activated potassium fluoride followed by 377 g of 3,4-dichlorobenzotrifluoride. At ambient temperature, 158 g of ammonia was vented from a pressure tank into the reactor. The reaction mixture was heated to 245-250 °C over a period of 2 h, at which time the reactor pressure reached 30-32 kg/cm2. excess ammonia gas was continued to be passed from the pressure tank to maintain the reactor pressure at 38-40 kg/cm2 at a liquid temperature of 245-250 °C. The reaction was maintained at this temperature and pressure condition for 8 h. The reaction was completed with the addition of 377 g of potassium fluoride, followed by the addition of 377 g of 3,4-dichlorobenzotrifluoride. Upon completion of the reaction, the mixture was cooled to ambient temperature and the unreacted ammonia gas was drained and recovered. The reaction mixture was filtered and the products were separated by fractional distillation to give 2-chloro-4-trifluoromethylaniline (77% yield) and 2-chloro-5-trifluoromethylaniline (13% yield) based on 3,4-dichlorobenzotrifluoride consumption calculations.

References

[1] Patent: WO2011/107998, 2011, A1. Location in patent: Page/Page column 17
[2] Patent: US2013/30190, 2013, A1. Location in patent: Paragraph 0060

3-Amino-4-chlorobenzotrifluoride synthesis

Synthesis of 3-Amino-4-chlorobenzotrifluoride from 3,4-Dichlorobenzotrifluoride

3-Amino-4-chlorobenzotrifluoride Preparation Products And Raw materials

Raw materials

3,4-Dichlorobenzotrifluoride Ammonia 3-CHLORO-2-NITROBENZOTRIFLUORIDE Potassium fluoride N-Methyl-2-pyrrolidone

4-Chloro-3-nitrobenzotrifluoride 4-Chlorobenzotrifluoride Water

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Preparation Products

2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 4-Amino-3-chlorobenzotrifluoride (2-CHLORO-5-TRIFLUOROMETHYL)PHENYLTHIOUREA 2-CHLORO-5-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 4-CHLORO-3-IODOBENZOTRIFLUORIDE

N-[2-chloro-5-(trifluoromethyl)phenyl]-3-oxobutanamide N-(4-{[2-chloro-5-(trifluoromethyl)anilino]sulfonyl}phenyl)acetamide Benzamide, 5-chloro-N-(2,4-difluorophenyl)-2-hydroxy-

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3-Amino-4-chlorobenzotrifluoride Suppliers

Global( 409)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5231	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	967	58
Henan Xiangtong Chemical Co., Ltd.	86-371-61312303	info@hnxtchem.com	CHINA	292	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Worldyang Chemical Co.,Ltd.	58
Henan Xiangtong Chemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58

View Lastest Price from 3-Amino-4-chlorobenzotrifluoride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	3-Amino-4-chlorobenzotrifluoride 121-50-6	$18.60	1KG	99%	5000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-04-17	3-Amino-4-chlorobenzotrifluoride 121-50-6	$2.00-5.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2026-03-20	3-Amino-4-chlorobenzotrifluoride 121-50-6	$10.00	1KG	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

3-Amino-4-chlorobenzotrifluoride
121-50-6
$18.60
99%
Hebei Chuanghai Biotechnology Co,.LTD

3-Amino-4-chlorobenzotrifluoride
121-50-6
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

3-Amino-4-chlorobenzotrifluoride
121-50-6
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

3-Amino-4-chlorobenzotrifluoride Spectrum

3-Amino-4-chlorobenzotrifluoride(121-50-6)MS 3-Amino-4-chlorobenzotrifluoride(121-50-6)¹HNMR 3-Amino-4-chlorobenzotrifluoride(121-50-6)¹³CNMR 3-Amino-4-chlorobenzotrifluoride(121-50-6)IR1

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6-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUIDINE 4-CHLORO-A,A,A-TRIFLUORO-M-TOLUIDINE 4-CHLORO-3-AMINOBENZOTRIFLUORIDE 3-AMINO-4-CHLOROTRIFLUOROTOLUENE 3-AMINO-4-CHLORO-A,A,A-TRIFLUOROTOLUENE 3-AMINO-4-CHLOROBENZOTRIFLUORIDE 2-chloro-5-(trifluoromethyl)-benzenamin 3-Amino-4-chloro-alpha,alpha,alpha-trifluorotoluene 6-Chloro-3-(trifluoromethyl)aniline 2-Chloro-5-(tr Chloro-5-(trifluoroMethyl)an 2-Chloro-5-(trifluoromethyl)aniline, 6-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine 3-Amino-4-chorobenzotrifluoride 6-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine 3-Amino-4-chlorobenzotrifluoride C.I. 37050 3-Amino-4-chlorobenzotrifluoride for synthesis 2-Chloro-5-(trifluoromethyl)aniline >=98.0% (GC) 4-chloro-3-aminotrifluorotoluene 3-Amino-4-chlorobenzotrifluoride, 6-Chloro-α,α,α-trifluoro-m-toluidine Azoene Fast Orange RD 3-Amino-4-chlorobenzotrifluoride ,97% C.I.Azoic Diazo Component 49 TIMTEC-BB SBB003593 LABOTEST-BB LT00053884 FAST ORANGE RD OIL C.I. 37050 3-Amino-4-Chloro-(Trifluoromethyl)Benzene 3-maino-4-chloro-benzotrifluoride 5-Chloro-2-(trifluoromethyl)benzenamine 3-AMINO-4-CHLOROBENZOTRIFLUORIDE 99% 1-AMINO-2-CHLORO-5-(TRIFLUORMETHYL)-BENZENE 3-Amino-4-chlorobenzotrifluoride98% 6-Chlor-.alpha,alpha,alpha-trifluor-m-toluidin AKOS BBS-00000946 6-CHLORO-A,A,A-TRIFLUORO-M-TOLUIDINE 6-chloro-alpha,alpha,alpha-trifluoro-m-toluidin Azoene Fast Orange RD Salt azoenefastorangerdsalt Benzenamine,2-chloro-5-(trifluoromethyl)- Daito Orange Salt RD daitoorangesaltrd Diazo Fast Orange RD diazofastorangerd Fast Orange RD Salt Fast Orange Salt RD Fast Orange Salt RDA Fast Orange Salt RDN fastorangerdsalt fastorangesaltrd fastorangesaltrda fastorangesaltrdn Hiltosal Fast Orange RD Salt hiltosalfastorangerdsalt m-Toluidine, 6-chloro-alpha,alpha,alpha-trifluoro- Orange Salt NRD orangesaltnrd Sanyo Fast Orange Salt RD sanyofastorangesaltrd USAF ma-13