Lynestrenol
- CAS No.
- 52-76-6
- Chemical Name:
- Lynestrenol
- Synonyms
- 17-alpha-ethinyl-17-beta-hydroxyoestr-4-ene;exluten;exluton;lynenol;LYNDIOL;exlution;exlutona;Exlutena;nsc-37725;org485-50
- CBNumber:
- CB2441014
- Molecular Formula:
- C20H28O
- Molecular Weight:
- 284.44
- MDL Number:
- MFCD00051135
- MOL File:
- 52-76-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 158°C |
|---|---|
| alpha | D -13° (chloroform) |
| Boiling point | 366.92°C (rough estimate) |
| Density | 1.0083 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, soluble in acetone and in ethanol (96 per cent). |
| pka | 13.12±0.40(Predicted) |
| form | Solid |
| color | Crystals from MeOH |
| Merck | 14,5629 |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1 |
| InChIKey | YNVGQYHLRCDXFQ-XGXHKTLJSA-N |
| SMILES | O[C@@]1([C@@]2([C@H]([C@H]3[C@@H]([C@H]4CCCC=C4CC3)CC2)CC1)C)C#C |
| CAS DataBase Reference | 52-76-6 |
| EWG's Food Scores | 1 |
| FDA UNII | N2Z8ALG4U5 |
| Proposition 65 List | Lynestrenol |
| ATC code | G03AC02,G03DC03 |
| EPA Substance Registry System | Lynestrenol (52-76-6) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H351-H361 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| RTECS | RC8964300 |
| HS Code | 2937230000 |
| Hazardous Substances Data | 52-76-6(Hazardous Substances Data) |
Lynestrenol price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001034 | Lynestrenol for peak identification European Pharmacopoeia (EP) Reference Standard | 52-76-6 | 20 mg | $127 | 2026-04-30 | Buy |
| Sigma-Aldrich | L0800000 | Lynestrenol European Pharmacopoeia (EP) Reference Standard | 52-76-6 | 50 mg | $164 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1370906 | Lynestrenol | 52-76-6 | 20mg | $542 | 2026-04-30 | Buy |
| Sigma-Aldrich | L0800000 | Lynestrenol European Pharmacopoeia (EP) Reference Standard | 52-76-6 | l0800000 | $150 | 2024-03-01 | Buy |
| Usbiological | 281361 | Lynestrenol Asreported | 52-76-6 | 2mg | $337 | 2026-06-03 | Buy |
Lynestrenol Chemical Properties, Uses, Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Lynestrenol is an orally available progestogen hormone used in contraception to avoid hereditary angiodema as well as in treatment of ischemic stroke.
Uses
Progestogen;Antioestrogen
Definition
ChEBI: Lynestrenol is a steroid. It derives from a hydride of an estrane.
brand name
Anacycline 101;Anacylin 101;Anacylin 28;Ancylin;Athilyn;Endometril;Exluton (a);Fysiognens;Fysionorm;Gestrol;Lindiol 2.5;Lyn_ratiopharm;Lyn_ratiophram_sequenz;Lyndeol;Lyndile tt;Lyndiol e.;Lyndiolett;Lynoenstrenol;Lyn-ratiopharm;Mini pregnon;Minifol;Minilyn;Neo lyndiol;Neo-lindiol;Neo-lynobol;Nonovulet;Noracyclin 22;Normophasic;Novostat;Org 485-50;Orgaluton;Orgametrol;Ovamezzo;Ovanone;Ovanon-e;Ovariostat;Ovoresta micro;Ovostat-28;Ovostat-micro;Phasicon;Physiostat;Physistat;Pregnon-28;Restovar.
World Health Organization (WHO)
Lynestrenol, a synthetic progestogen, was introduced in the early 1960s as a component in oral contraceptive preparations. In 1967, as a result of new regulations required by the United States Food and Drug Administration, lynestrenol was submitted to long-term toxicity studies and by the early 1970s it was shown to be associated with an increased incidence of mammary tumours in beagle bitches which led to its withdrawal by at least one regulatory authority. Subsequently the validity of the beagle bitch model as a predictor of carcinogenicity of steroid contraceptives has been contested by many national regulatory authorities and lynestrenol remains available in some countries for contraceptive and other purposes. (Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984)
Safety Profile
An experimental teratogen.Experimental reproductive effects. Human reproductiveeffects by ingestion and implant routes: menstrual cyclechanges or disorders, female fertility index, other fertilitychanges and effects on females. Questionable carcinoge
Lynestrenol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
View Latest Price from Lynestrenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Lynestrenol
52-76-6
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-09-16 | Lynestrenol
52-76-6
|
1g | 98.0%-102.0%;BP | 100 KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-08 | Lynestrenol
52-76-6
|
1g | 98.0%(LC) | 100kg | Hangzhou ICH Biofarm Co., Ltd |
-
- Lynestrenol
52-76-6
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Lynestrenol
52-76-6
- $0.00
- 98.0%-102.0%;BP
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Lynestrenol
52-76-6
- 98.0%(LC)
- Hangzhou ICH Biofarm Co., Ltd
