2,6-Dibromo-3-hydroxypyridine
- CAS No.
- 6602-33-1
- Chemical Name:
- 2,6-Dibromo-3-hydroxypyridine
- Synonyms
- 2,6-dibromopyridin-3-ol;3-Pyridinol, 2,6-dibromo-;2,6-Dibromo-3-hydroxypyridine;2,6-DIBROMO-3-HYDROXYPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB2443568
- Molecular Formula:
- C5H3Br2NO
- Molecular Weight:
- 252.89
- MDL Number:
- MFCD01318479
- MOL File:
- 6602-33-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 164.0 to 168.0 °C |
|---|---|
| Boiling point | 369.3±37.0 °C(Predicted) |
| Density | 2.228±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.86±0.10(Predicted) |
| color | White to Light yellow |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H302-H319 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2,6-Dibromo-3-hydroxypyridine price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5174 | 2,6-Dibromo-3-hydroxypyridine >97.0%(T) | 6602-33-1 | 1g | $78 | 2026-04-30 | Buy |
| Apolloscientific | OR346545 | 2,6-Dibromopyridin-3-ol 97% | 6602-33-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR346545 | 2,6-Dibromopyridin-3-ol 97% | 6602-33-1 | 5g | $39 | 2026-06-04 | Buy |
| Apolloscientific | OR346545 | 2,6-Dibromopyridin-3-ol 97% | 6602-33-1 | 25g | $131 | 2026-06-04 | Buy |
| Apolloscientific | OR346545 | 2,6-Dibromopyridin-3-ol 97% | 6602-33-1 | 100g | $512 | 2026-06-04 | Buy |
2,6-Dibromo-3-hydroxypyridine Chemical Properties, Uses, Production
Synthesis
109-00-2
6602-33-1
General procedure for the synthesis of 2,6-dibromo-3-hydroxypyridine from 3-hydroxypyridine: Ice-cold bromine (16.2 mL, 315 mmol) was added dropwise to a stirring 2.5 M sodium hydroxide solution (320 mL, 800 mmol). This mixed solution was then slowly added to a 2.5 M sodium hydroxide solution (110 mL, 275 mmol) containing 3-hydroxypyridine (10.0 g, 105 mmol). The reaction mixture was stirred at 0 °C for 1 hour, followed by continued stirring at room temperature for 4 hours. Upon completion of the reaction, a small amount of precipitate was removed by filtration. The filtrate was cooled and the pH was adjusted to 1 with concentrated hydrochloric acid, at which point a solid precipitated. The solid product was collected by filtration, washed with water, dried, and recrystallized from carbon tetrachloride to give 2,6-dibromo-3-hydroxypyridine (12.1 g, 46% yield) as a beige solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ= 11.14 (br s, 1H), 7.47 (d, J = 8.0 Hz, 1H), 7.26 (d, J = 8.0 Hz, 1H); mass spectra (ES-ve) m/z: 250, 252, 254 (M-H)-.
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 15, p. 4298 - 4311
[2] Australian Journal of Chemistry, 1981, vol. 34, # 4, p. 927 - 932
[3] Patent: WO2010/56549, 2010, A1. Location in patent: Page/Page column 97
[4] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5630 - 5634
[5] Patent: WO2013/181931, 2013, A1. Location in patent: Page/Page column 40
2,6-Dibromo-3-hydroxypyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 974 | 65 |
| Pharmsynth Pharmaceutical (Chengdu) Technology Co.,LTD | 15528092102 | Pharmsynth@hotmail.com | China | 116 | 60 |
| Baiyin Chengze Chemical Technology Co., Ltd. | +86 943-8535351 13389336721 | sales@chengzechem.com | China | 300 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from 2,6-Dibromo-3-hydroxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2,6-DIBROMO-3-HYDROXYPYRIDINE
6602-33-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-12 | 2,6-DIBROMO-3-HYDROXYPYRIDINE
6602-33-1
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2,6-DIBROMO-3-HYDROXYPYRIDINE
6602-33-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,6-DIBROMO-3-HYDROXYPYRIDINE
6602-33-1
- $1.00
- 99%
- Career Henan Chemical Co
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