3-Hydroxypyridine
- CAS No.
- 109-00-2
- Chemical Name:
- 3-Hydroxypyridine
- Synonyms
- PYRIDIN-3-OL;3-PYRIDINOL;3-HP;3-PYRIDOL;3-PYRIDONE;2(1H)-PYRIDONE;pyridin-3(4H)-one;NSC 18470;2-PYRIDON;B-PYRIDONE
- CBNumber:
- CB6852775
- Molecular Formula:
- C5H5NO
- Molecular Weight:
- 95.1
- MDL Number:
- MFCD00006378
- MOL File:
- 109-00-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 125-128 °C (lit.) |
|---|---|
| Boiling point | 280-281 °C(lit.) |
| Density | 1.1418 (rough estimate) |
| refractive index | 1.5939 (estimate) |
| Flash point | 173°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 33g/l |
| form | Crystalline Powder |
| pka | 4.79, 8.75(at 20℃) |
| color | Beige to brown |
| PH | 6.0-6.5 (33g/l, H2O, 20℃) |
| Water Solubility | 32.26g/L(20 ºC) |
| BRN | 105699 |
| InChI | 1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H |
| InChIKey | GRFNBEZIAWKNCO-UHFFFAOYSA-N |
| SMILES | Oc1cccnc1 |
| LogP | 0.480 |
| CAS DataBase Reference | 109-00-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4KBE4P5B6S |
| NIST Chemistry Reference | 3-Pyridinol(109-00-2) |
| EPA Substance Registry System | 3-Pyridinol (109-00-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-40 | |||||||||
| Safety Statements | 26-36-37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UV1144050 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29333999 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
3-Hydroxypyridine price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H57009 | 3-Hydroxypyridine 98% | 109-00-2 | 25g | $42.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | H57009 | 3-Hydroxypyridine 98% | 109-00-2 | 100g | $50.8 | 2026-04-30 | Buy |
| TCI Chemical | H0331 | 3-Hydroxypyridine >98.0%(GC)(T) | 109-00-2 | 25g | $42 | 2026-04-30 | Buy |
| TCI Chemical | H0331 | 3-Hydroxypyridine >98.0%(GC)(T) | 109-00-2 | 100g | $104 | 2026-04-30 | Buy |
| Usbiological | 278634 | 3-Hydroxypyridine ≥98% | 109-00-2 | 250g | $333 | 2026-06-03 | Buy |
3-Hydroxypyridine Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal. Soluble in alcohol and water, slightly soluble in ether and benzene. It becomes a red solution when it encounters ferric chloride, and it is easy to decompose in the air.
Uses
3-Hydroxypyridine (cas# 109-00-2) is a compound useful in organic synthesis.
Preparation
3-hydroxypyridine was prepared by reacting furfurylamine with H2O2 in the presence of HCl, followed by hydrolysis. The optimal conditions were found as fellows: molar ratio of furfurylamine: HCl : H2O2 = 1 : 5 : 1.1, and H2O2 added dropwisely at 0-5 °C, and then refluxed at 100-105 °C for 0.5 h.
Definition
ChEBI: 3-Hydroxypyridine is a monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant.
brand name
Ventavis (Schering).
Purification Methods
Crystallise 3-hydroxypyridine from *C6H6, water or EtOH. [Beilstein 21 III/IV 402, 21/2 V 68.]
3-Hydroxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lianyungang Shenghe Biotechnology Co., Ltd. | 0518-87108777 13585296001 | haizaofu@163.com | China | 44 | 58 |
| Yancheng Huahong Chemical Co., Ltd. | 15366451979 | sales@huahongchem.com | China | 23 | 58 |
| Jinan Dexinjia Bio&Tech Co., Ltd | 0531-82375880 15098789112 | 3845379039@qq.com | China | 1457 | 58 |
| Fuxin Kaituo Fine Chemical Technology Co., Ltd | 15714082442 | 3757845877@qq.com | China | 343 | 58 |
| Nanjing Yihua Biotechnology Co., Ltd | 13429882898; 13429882898 | 1096323105@qq.com | China | 291 | 58 |
| Shandong Shenganbei New Energy Co. , Ltd. . Nanjing branch | 18761883648 | sab202211@163.com | China | 1672 | 58 |
| Beijing Dongxing Science and Technology Co.,Ltd | 15801121354; 15801121354 | dx_chem@sina.com | China | 23 | 58 |
| Jinan Shengbang Biotechnology Co., Ltd. | 13685312009 | 418162321@qq.com | China | 60 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
View Latest Price from 3-Hydroxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | 3-Hydroxypyridine
109-00-2
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-20 | 3-Hydroxypyridine
109-00-2
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-05-28 | 3-Hydroxypyridine
109-00-2
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 3-Hydroxypyridine
109-00-2
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 3-Hydroxypyridine
109-00-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Hydroxypyridine
109-00-2
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
