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RO-5963

RO-5963 Structure
RO-5963 structure
CAS No.
1416663-77-8
Chemical Name:
RO-5963
Synonyms
RO-5963;RO5963,RO 5963;RO-5963, 10 mM in DMSO;1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-α-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo-
CBNumber:
CB24668451
Molecular Formula:
C24H21ClF2N4O5
Molecular Weight:
518.9
MDL Number:
MFCD32067934
MOL File:
1416663-77-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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RO-5963 Properties

Density 1.562±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 7.71±0.20(Predicted)
form Solid
color Light yellow to yellow

RO-5963 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0069466 RO-5963 98.19% 1416663-77-8 1mg $91 2026-06-04 Buy
ChemScene CS-0069466 RO-5963 98.19% 1416663-77-8 5mg $227 2026-06-04 Buy
ChemScene CS-0069466 RO-5963 98.19% 1416663-77-8 10mg $314 2026-06-04 Buy
ChemScene CS-0069466 RO-5963 98.19% 1416663-77-8 25mg $487 2026-06-04 Buy
ChemScene CS-0069466 RO-5963 98.19% 1416663-77-8 50mg $650 2026-06-04 Buy
Product number Packaging Price Buy
CS-0069466 1mg $91 Buy
CS-0069466 5mg $227 Buy
CS-0069466 10mg $314 Buy
CS-0069466 25mg $487 Buy
CS-0069466 50mg $650 Buy

RO-5963 Chemical Properties, Uses, Production

Description

RO-5963 is an inhibitor of the interaction of both MDM2 and MDMX with p53.

Uses

RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively[1].

References

[1] Graves B, et al. Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11788-93. DOI:10.1073/pnas.1203789109

RO-5963 Preparation Products And Raw materials

Raw materials

Preparation Products

RO-5963 Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhengzhou Alpha Chemical Co. LTD 0371-53732842 13383863444 3838551451@qq.com China 9989 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 9998 58
Supplier Advantage
TargetMol Chemicals Inc. 58
Zhengzhou Alpha Chemical Co. LTD 58
cjbscvictory 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Beijing Boorsen Biotechnology Co., Ltd 58
RD International Technology Co., Limited 58
Shanghai Amole Biotechnology Co., Ltd. 58
Guangzhou Ruidi Biotechnology Co., Ltd. 58

View Latest Price from RO-5963 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RO-5963 pictures 2026-07-27 RO-5963
1416663-77-8
 $64.00-239.00 99.36% 10g TargetMol Chemicals Inc.
  • RO-5963 pictures
  • RO-5963
    1416663-77-8
  • $64.00-239.00
  • 99.36%
  • TargetMol Chemicals Inc.

RO-5963 Spectrum

RO-5963(1416663-77-8)1HNMR

1416663-77-8 (RO-5963) Related Search:

RO 2443 RO-5963 UBA1 Protein, Human (sf9, His-GST) UBA5 Protein, Human (His) UBE2A Protein, Human (GST-His)
WWP2 Protein, Human (sf9, His-GST)

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RO-5963 RO5963,RO 5963 1-Imidazolidineacetamide, 4-[(6-chloro-7-methyl-1H-indol-3-yl)methylene]-α-(3,4-difluorophenyl)-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-2,5-dioxo- RO-5963, 10 mM in DMSO 1416663-77-8