OGERIN NEGATIVE CONTROL
- CAS No.
- 1125453-08-8
- Chemical Name:
- OGERIN NEGATIVE CONTROL
- Synonyms
- OGERIN NEGATIVE CONTROL;Ogerin negative control >=98% (HPLC);Benzenemethanol, 3-[4-amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]-
- CBNumber:
- CB24740261
- Molecular Formula:
- C17H17N5O
- Molecular Weight:
- 307.35
- MDL Number:
- MFCD29472590
- MOL File:
- 1125453-08-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 623.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 20mg/mL, clear |
| form | powder |
| pka | 14.14±0.10(Predicted) |
| color | white to beige |
| InChI | 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) |
| InChIKey | RVKAHYFWSKSSQQ-UHFFFAOYSA-N |
| SMILES | NC1=NC(C2=CC(CO)=CC=C2)=NC(NCC3=CC=CC=C3)=N1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
OGERIN NEGATIVE CONTROL price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1483 | Ogerin negative control ≥98% (HPLC) | 1125453-08-8 | 5MG | $101 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1483 | Ogerin negative control ≥98% (HPLC) | 1125453-08-8 | 25MG | $380 | 2025-07-31 | Buy |
| Biosynth | AVB45308 | Ogerin negative control | 1125453-08-8 | 25mg | $822 | 2026-06-04 | Buy |
| Biosynth | AVB45308 | Ogerin negative control | 1125453-08-8 | 50mg | $1315 | 2026-06-04 | Buy |
| Biosynth | AVB45308 | Ogerin negative control | 1125453-08-8 | 100mg | $1830 | 2026-06-04 | Buy |
OGERIN NEGATIVE CONTROL Chemical Properties,Uses,Production
Uses
Ogerin analogue 1 (compound 20) is a structural analog of Ogerin (HY-110279). Ogerin analogue 1 is generally used as a negative control[1].
Biochem/physiol Actions
Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.
References
[1] Yu X, et al. Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68). J Med Chem. 2019 Aug 22;62(16):7557-7574. DOI:10.1021/acs.jmedchem.9b00869
OGERIN NEGATIVE CONTROL Preparation Products And Raw materials
Raw materials
Preparation Products
OGERIN NEGATIVE CONTROL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Energy Chemical | 58 |
