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(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone

(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone structure

CAS No.: 132861-87-1

Chemical Name:: (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone

Synonyms: PD 81,723;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone;(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone

CBNumber:: CB2484082

Molecular Formula:: C14H12F3NOS

Molecular Weight:: 299.31

MDL Number:: MFCD01321053

MOL File:: 132861-87-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:51:19

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(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Properties

Melting point	100-104 °C(Solv: ligroine (8032-32-4))
Boiling point	411.7±45.0 °C(Predicted)
Density	1.328±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	DMSO: ~13 mg/mL
form	solid
pka	-1.36±0.13(Predicted)
color	yellow

SAFETY

Risk and Safety Statements

WGK Germany	3

(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	42371	PD 81723 ≥95%	132861-87-1	5mg	$98	2026-04-30	Buy
Cayman Chemical	42371	PD 81723 ≥95%	132861-87-1	10mg	$157	2026-04-30	Buy
Cayman Chemical	42371	PD 81723 ≥95%	132861-87-1	25mg	$368	2026-04-30	Buy
Usbiological	256193	PD 81723 Asreported	132861-87-1	10mg	$403	2026-06-03	Buy
Usbiological	256193	PD 81723 Asreported	132861-87-1	50mg	$990	2026-06-03	Buy

Product number	Packaging	Price	Buy
42371	5mg	$98	Buy
42371	10mg	$157	Buy
42371	25mg	$368	Buy
256193	10mg	$403	Buy
256193	50mg	$990	Buy

(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Chemical Properties, Uses, Production

Uses

PD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.

Biological Activity

Allosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .

storage

Store at RT

(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Preparation Products And Raw materials

Raw materials

Preparation Products

(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Suppliers

Global Suppliers ( 42)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Aikon International Limited	025-58859352 19370895928	sales01@aikonchem.com	China	15078	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58
Shanghai Universal Biotech Co.,Ltd	15921930842 15921930842	yh-wang@univ-bio.com	China	25030	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24951	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BOC Sciences	65
EMMX Biotechnology LLC	60
Shanghai YuanYe Biotechnology Co., Ltd.	60
Amadis Chemical Company Limited	58
Aikon International Limited	58
TargetMol Chemicals Inc.	58
Energy Chemical	58
Shanghai Universal Biotech Co.,Ltd	58
TargetMol Chemicals Inc.	58

View Latest Price from (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	PD 81723 132861-87-1	$143.00-533.00		99.97%	10g	TargetMol Chemicals Inc.

PD 81723
132861-87-1
$143.00-533.00
99.97%
TargetMol Chemicals Inc.

132861-87-1 ((2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone) Related Search:

2-Amino-3-benzoyl-4,5-dimethylthiophene (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone 3-(3-Methylbenzoyl)thiophene 3-Benzoylthiophene 3-(3-Trifluoromethylbenzoyl)thiophene

(2-Amino-3-thienyl)(phenyl)methanone

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(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone PD 81,723 (2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone (3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone 4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]- (2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone 132861-87-1 C14H12F3NOS Adenosine receptor