Suprofen
- CAS No.
- 40828-46-4
- Chemical Name:
- Suprofen
- Synonyms
- Profenol;Suprol;TN 762;r25061;Anemet;Srendam;Suprocil;Topalgic;Profenal;maldocil
- CBNumber:
- CB2496867
- Molecular Formula:
- C14H12O3S
- Molecular Weight:
- 260.31
- MDL Number:
- MFCD00079572
- MOL File:
- 40828-46-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 278°C |
|---|---|
| Boiling point | 373.57°C (rough estimate) |
| Density | 1.2959 (rough estimate) |
| refractive index | 1.5050 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.5 mg/ml |
| pka | 3.91(at 25℃) |
| form | Powder |
| color | White to off-white |
| Water Solubility | soluble |
| InChI | InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17) |
| InChIKey | MDKGKXOCJGEUJW-UHFFFAOYSA-N |
| SMILES | C1(=CC=C(C(C)C(=O)O)C=C1)C(=O)C1SC=CC=1 |
| CAS DataBase Reference | 40828-46-4(CAS DataBase Reference) |
| FDA UNII | 988GU2F9PE |
| ATC code | M01AE07 |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P330+P331+P310 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2934990002 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral | |||||||||
| Toxicity | LD50 (7 days post-drug) in mice, rats, guinea pigs, dogs (mg/kg): 590, 353, 280, 160 orally (Niemegeers) | |||||||||
| NFPA 704 |
|
Suprofen price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1495 | Suprofen ≥98% (HPLC) | 40828-46-4 | 5MG | $89 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1495 | Suprofen ≥98% (HPLC) | 40828-46-4 | 25MG | $288 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1642507 | Suprofen United States Pharmacopeia (USP) Reference Standard | 40828-46-4 | 200MG | $277 | 2026-04-30 | Buy |
| TCI Chemical | U0138 | Suprofen min. 98.0 % | 40828-46-4 | 25MG | $86 | 2026-04-30 | Buy |
| TCI Chemical | U0138 | Suprofen min. 98.0 % | 40828-46-4 | 100MG | $259 | 2026-04-30 | Buy |
Suprofen Chemical Properties, Uses, Production
Description
Suprofen is an arylpropionic acid analgesic/antiinflammatory agent with close structural resemblance to ketoprofen. It is more potent in many assays than indomethacin and ketoprofen and appears better tolerated.
Chemical Properties
Off-White to Light-Brown
Originator
Janssen (Belgium)
Uses
Prostaglandin biosynthesis inhibitor. Analgesic
Uses
Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.
Definition
ChEBI: An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
brand name
Profenal (Alcon);Algiamida;Algiasdi;Bordol;Erdol;Masterfen;Sufenid;Supranol;Surfex;MALDOCIL.
Veterinary Drugs and Treatments
Suprofen is a non-steroidal anti-inflammatory agent similar to flurbiprofen. Suprofen and flurbiprofen are phenylalkanoic acids that inhibit the cyclo-oxygenase enzymes responsible for conversion of arachadonic acid from cell membranes into various prostaglandins. These prostaglandins mediate certain aspects of ocular inflammation including disruption of the blood-aqueous barrier, uveal vasodilation, increases in intraocular pressure, and leakage of white blood cells and protein from uveal vessels into the aqueous humor. Prostaglandins cause iris sphincter constriction (miosis) independent of cholinergic mechanisms. Suprofen can inhibit this intraocular miosis and may also be useful in the management of uveal inflammation (usually in addition to topical steroids).
Suprofen Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Suprofen Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sangel Pharmaceutical & Chemical Factory | 0571-0571-85773987 13505717485 | 1610413282@qq.com | China | 70 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
View Latest Price from Suprofen manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Suprofen
40828-46-4
|
1g | 98%-102% | 100G | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-20 | Suprofen USP/EP/BP
40828-46-4
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-07-27 | Suprofen
40828-46-4
|
$59.00-198.00 | 99.33% | 10g | TargetMol Chemicals Inc. |
-
- Suprofen
40828-46-4
- 98%-102%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Suprofen USP/EP/BP
40828-46-4
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Suprofen
40828-46-4
- $59.00-198.00
- 99.33%
- TargetMol Chemicals Inc.
