ChemicalBook >> CAS DataBase List >>4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

CAS No.
53005-05-3
Chemical Name:
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
Synonyms
DIDS, Disodium Salt - CAS 53005-05-3;4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid;2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
CBNumber:
CB2683689
Molecular Formula:
C16H10N2O6S4
Molecular Weight:
454.52
MDL Number:
MFCD00065493
MOL File:
53005-05-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:43:19
Product description Number Pack Size Price
DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem 309795 250mg $217
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid 97% MT-10026 50g $628
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid 97% MT-10026 50g $628
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% CHM0024866 1G $671.86
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% CHM0024866 5G $1052.67

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Properties

Melting point >400°C
Density 1.54±0.1 g/cm3(Predicted)
pka -1.32±0.50(Predicted)
FDA UNII QHR3Z2PN8M

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HazardClass  IRRITANT-HARMFUL

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 309795 DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem 53005-05-3 250mg $217 2026-04-30 Buy
AHH MT-10026 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid 97% 50g $628 2026-05-26 Buy
AHH MT-10026 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid 97% 50g $628 2026-05-25 Buy
American Custom Chemicals Corporation CHM0024866 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% 53005-05-3 1G $671.86 2021-12-16 Buy
American Custom Chemicals Corporation CHM0024866 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 95.00% 53005-05-3 5G $1052.67 2021-12-16 Buy
Product number Packaging Price Buy
309795 250mg $217 Buy
MT-10026 50g $628 Buy
MT-10026 50g $628 Buy
CHM0024866 1G $671.86 Buy
CHM0024866 5G $1052.67 Buy

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot

Uses

Ion channel inhibitor; especially of anion transport.

Definition

ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid.

General Description

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.

Biochem/physiol Actions

Primary TargetCl- uptake

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Suppliers

Global( 32)Suppliers
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TargetMol Chemicals Inc.
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Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35896 56
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID 2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid) 4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid 4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato- 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid 4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid DIDS, Disodium Salt - CAS 53005-05-3 53005-05-3 C16H10N2O6S4 Cross Linking Reagents Fluorescent Labels & Indicators