4 4'-Diisothiocyanato-2 2'-stilbenedisu&
- CAS No.
- 207233-90-7
- Chemical Name:
- 4 4'-Diisothiocyanato-2 2'-stilbenedisu&
- Synonyms
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-D;4 4'-Diisothiocyanato-2 2'-stilbenedisu&;Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate;DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate;Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate;4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT;disodium 2,2'-(E)-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonate);4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate;4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate;4,4μ-Diisothiocyanatostilbene-2,2μ-disulfonic acid hydrate disodium salt
- CBNumber:
- CB6499068
- Molecular Formula:
- C16H13N2NaO7S4
- Molecular Weight:
- 496.52
- MDL Number:
- MFCD00009638
- MOL File:
- 207233-90-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | 2-8°C |
|---|---|
| solubility | 0.1 M potassium bicarbonate: soluble50mg/mL |
| form | powder |
| color | yellow |
| BRN | 8179433 |
| InChI | 1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2-1+;; |
| InChIKey | GEPAYBXVXXBSKP-SEPHDYHBSA-L |
| SMILES | [Na+].[Na+].[O-]S(=O)(=O)c1cc(ccc1\C=C\c2ccc(cc2S([O-])(=O)=O)N=C=S)N=C=S |
| UNSPSC Code | 12352200 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 22-26 |
| WGK Germany | 3 |
| HS Code | 29309090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3 |
4 4'-Diisothiocyanato-2 2'-stilbenedisu& price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3514 | 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate ≥80% (elemental analysis), powder | 207233-90-7 | 25mg | $60 | 2023-01-07 | Buy |
| Sigma-Aldrich | D3514 | 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate ≥80% (elemental analysis), powder | 207233-90-7 | 1g | $529 | 2022-05-15 | Buy |
| Biosynth | HIA23390 | 4,4′-Diisothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate | 207233-90-7 | 250mg | $900 | 2026-06-04 | Buy |
| Biosynth | HIA23390 | 4,4′-Diisothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate | 207233-90-7 | 500mg | $1170 | 2026-06-04 | Buy |
| Apolloscientific | BID2117 | Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate 90% | 207233-90-7 | 50mg | $96 | 2026-06-04 | Buy |
4 4'-Diisothiocyanato-2 2'-stilbenedisu& Chemical Properties, Uses, Production
Uses
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:
- as band3 protein inhibitor in rabbits(19)
- for the inhibition of bicarbonate transporters in brain slice tissue(20)
- as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)
reaction suitability
reagent type: cross-linking reagent
Biochem/physiol Actions
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.
4 4'-Diisothiocyanato-2 2'-stilbenedisu& Preparation Products And Raw materials
Raw materials
Preparation Products
4 4'-Diisothiocyanato-2 2'-stilbenedisu& Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Artis Chemistry (Shanghai) Co. Ltd. | 86-21-60936353 | China | 335 | 58 | |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9872 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5037 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| JiangSu Star Science Co.,Ltd | 400-605-7200 15335295587 | 3941881028@qq.com | China | 3755 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29676 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 9968 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53589 | 58 |
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