2-Methylene-1,3-propanediol
- CAS No.
- 3513-81-3
- Chemical Name:
- 2-Methylene-1,3-propanediol
- Synonyms
- 2-Methylene-1;2-methylene-3-propanediol;1-（4-pyridinyl) acetone;2-methylenepropane-1,3-diol;2-METHYLENE-1,3-PROPANEDIOL;2-Methylidenepropane-1,3-diol;1,3-Propanediol, 2-methylene-;2-Methylene-1,3-propanediol>2-Methylene-1,3-propanediol 97%;2-METHYLENE-1,3-PROPANEDIOL,97+%
- CBNumber:
- CB2684161
- Molecular Formula:
- C4H8O2
- Molecular Weight:
- 88.11
- MDL Number:
- MFCD00075162
- MOL File:
- 3513-81-3.mol
- MSDS File:
- SDS
| Boiling point | 93-95 °C/2 mmHg (lit.) |
|---|---|
| Density | 1.081 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 14.14±0.10(Predicted) |
| form | Viscous Liquid |
| color | Clear colorless to pale yellow |
| BRN | 1737653 |
| InChI | InChI=1S/C4H8O2/c1-4(2-5)3-6/h5-6H,1-3H2 |
| InChIKey | JFFYKITVXPZLQS-UHFFFAOYSA-N |
| SMILES | C(O)C(=C)CO |
| CAS DataBase Reference | 3513-81-3(CAS DataBase Reference) |
| EPA Substance Registry System | 1,3-Propanediol, 2-methylene- (3513-81-3) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29053990 | |||||||||
| NFPA 704 |
|
2-Methylene-1,3-propanediol price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 339512 | 2-Methylene-1,3-propanediol 97% | 3513-81-3 | 5g | $133.95 | 2025-07-31 | Buy |
| TCI Chemical | M2473 | 2-Methylene-1,3-propanediol >96.0%(GC) | 3513-81-3 | 1g | $35 | 2025-07-31 | Buy |
| TCI Chemical | M2473 | 2-Methylene-1,3-propanediol >96.0%(GC) | 3513-81-3 | 5g | $106 | 2025-07-31 | Buy |
| TRC | B494823 | 2-Methylene-1,3-propanediol | 3513-81-3 | 500mg | $60 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK193879 | 2-Methylene-1,3-propanediol 97% | 3513-81-3 | 1g | $79 | 2021-12-16 | Buy |
2-Methylene-1,3-propanediol Chemical Properties,Uses,Production
Chemical Properties
clear colorless to pale yellow viscous liquid
Synthesis
3775-29-9
3513-81-3
General procedure for the synthesis of 2-methylene-1,3-propanediol from 2-methylenepropane-1,3-diyl diacetate: allyl alcohol (1 eq.) was dissolved with acetic anhydride (1.2 eq.) in dichloromethane (DCM, concentration ca. 1 M) at 0 °C. Subsequently, pyridine (1 eq.) and 4-dimethylaminopyridine (DMAP, 0.1 mol%) were added to the reaction system. The reaction mixture was kept stirred at 0 °C for 30 min and then gradually warmed up to room temperature. After completion of the reaction, the reaction was quenched with 2N hydrochloric acid solution, the organic layer was separated, washed sequentially with water and brine and finally dried with anhydrous sodium sulfate. The solvent was removed by careful evaporation under reduced pressure to give pure 2-methylene propane-1,3-diyl diacetate (2d) without further purification. Subsequent processing was carried out via Method B. Specifically, purification by column chromatography (eluent ratio hexane:ethyl acetate = 20:1) afforded 2-methylene-1,3-propanediol as a colorless oil (20 g, 91% yield). The analytical data of the resulting compound were in agreement with literature reports.
References
[1] Patent: WO2018/53322, 2018, A1. Location in patent: Paragraph 0090; 00143
[2] J. Appl. Chem. USSR (Engl. Transl.), 1988, vol. 61, # 4, p. 853 - 855
[3] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1988, vol. 61, # 4, p. 934 - 937
[4] Synlett, 2008, # 15, p. 2321 - 2325
2-Methylene-1,3-propanediol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PNP Biotech Co. Ltd | +8618516098983 | sales@pnpbiotech.com | China | 1001 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
View Lastest Price from 2-Methylene-1,3-propanediol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 2-Methylene-1,3-propanediol
3513-81-3
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
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|
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2024-03-28 | 2-Methylene-1,3-propanediol
3513-81-3
|
US $0.00 / kg | 25kg | 98% | Inquiry | PNP Biotech Co. Ltd | |
 |
2019-09-02 | 2-Methylene-1,3-propanediol
3513-81-3
|
US $7.00 / KG | 1KG | 99% | 1000KG | Career Henan Chemical Co |
-
- 2-Methylene-1,3-propanediol
3513-81-3
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-Methylene-1,3-propanediol
3513-81-3
- US $0.00 / kg
- 98%
- PNP Biotech Co. Ltd
-
- 2-Methylene-1,3-propanediol
3513-81-3
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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