1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
- CAS No.
- 76697-50-2
- Chemical Name:
- 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
- Synonyms
- 2-(isopropylsulfonyl)a;2-propan-2-ylsulfonylaniline;2-(isopropylsulfonyl)aniline;2-(Isopropylsulphonyl)aniline;2-(propane-2-sulfonyl)aniline;2-AMinophenyl Isopropyl Sulfone;2-(isopropylsulfonyl)benzenaMine;2-(Isopropylsulphonyl)aniline 98%;2-(Propane-2-sulfonyl)-phenylaMine;1-Amino-2-(isopropylsulfonyl)benzene
- CBNumber:
- CB2727345
- Molecular Formula:
- C9H13NO2S
- Molecular Weight:
- 199.27
- MDL Number:
- MFCD08445603
- MOL File:
- 76697-50-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(Isopropylsulfonyl)aniline >98.0%(GC) | I1033 | 1g | $47 |
| 2-(Isopropylsulfonyl)aniline >98.0%(GC) | I1033 | 5g | $142 |
| 2-AminophenylIsopropylSulfone | A611880 | 1g | $120 |
| 2-Aminophenyl Isopropyl Sulfone | 159401 | 1g | $403 |
| 2-AminophenylIsopropylSulfone | A611880 | 5g | $415 |
| More product size | |||
| Melting point | 83.0 to 87.0 °C |
|---|---|
| Boiling point | 381.1±34.0 °C(Predicted) |
| Density | 1.194±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | solid |
| pka | -0.79±0.10(Predicted) |
| color | Beige |
| InChI | InChI=1S/C9H13NO2S/c1-7(2)13(11,12)9-6-4-3-5-8(9)10/h3-7H,10H2,1-2H3 |
| InChIKey | GMLAMRMKROYXNZ-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=CC=C1S(C(C)C)(=O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2930909899 | |||||||||
| NFPA 704 |
|
1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | I1033 | 2-(Isopropylsulfonyl)aniline >98.0%(GC) | 76697-50-2 | 1g | $47 | 2025-07-31 | Buy |
| TCI Chemical | I1033 | 2-(Isopropylsulfonyl)aniline >98.0%(GC) | 76697-50-2 | 5g | $142 | 2025-07-31 | Buy |
| TRC | A611880 | 2-AminophenylIsopropylSulfone | 76697-50-2 | 1g | $120 | 2021-12-16 | Buy |
| Usbiological | 159401 | 2-Aminophenyl Isopropyl Sulfone | 76697-50-2 | 1g | $403 | 2021-12-16 | Buy |
| TRC | A611880 | 2-AminophenylIsopropylSulfone | 76697-50-2 | 5g | $415 | 2021-12-16 | Buy |
1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Chemical Properties,Uses,Production
Uses
2-Aminophenyl Isopropyl Sulfone is a reagent used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment.
Synthesis
70415-86-0
76697-50-2
Step 3: Preparation of 2-(isopropylsulfonyl)aniline (4); 1-(isopropylsulfonyl)-2-nitrobenzene (3, 2 g, 8.73 mmol) was dissolved in methanol (25 ml) to form a homogeneous mixture. 10% palladium carbon (200 mg, 10 mol%) was added to the mixture and the reaction mixture was stirred under hydrogen atmosphere for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the complete conversion of feedstock 3 to product 4. Upon completion of the reaction, the mixture was filtered through diatomaceous earth, and the filtrate was concentrated under reduced pressure to afford 2-(isopropylsulfonyl)aniline (4, 1.73 g, quantitative yield).' HNMR (CDCl3): δ 7.66-7.62 (d, 1H), 7.40-7.30 (t, 1H), 6.85-6.78 (t, 1H), 6.73-6.70 (d, 1H), 5.10 (br s, 1H), 3.40-3.30 (m, 1H), 1.30 (s, 6H).
References
[1] Patent: WO2011/140338, 2011, A1. Location in patent: Page/Page column 46-47
[2] Patent: CN106854200, 2017, A. Location in patent: Paragraph 0064
[3] Patent: CN106146468, 2016, A. Location in patent: Paragraph 0088; 0101; 0102
[4] Patent: CN106336382, 2017, A. Location in patent: Paragraph 0099; 0141; 0142; 0143
[5] Patent: US2018/57457, 2018, A1. Location in patent: Paragraph 0260; 0262
1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13636 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-26 | 2-(Isopropylsulfonyl)aniline
76697-50-2
|
US $0.00-0.00 / kg | 0.1kg | 99%(HPLC) | 5000kg/Year | Nanjing Fred Technology Co., Ltd | |
 |
2023-05-04 | 2-(isopropyl sulfonyl) aniline
7669-50-2
|
US $48.00-40.00 / KG | 10公斤 | 99% | 200tons | Guangzhou Sunton Biotechnology Co., Ltd. | |
 |
2019-07-06 | 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
76697-50-2
|
US $100.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 2-(Isopropylsulfonyl)aniline
76697-50-2
- US $0.00-0.00 / kg
- 99%(HPLC)
- Nanjing Fred Technology Co., Ltd
-
- 2-(isopropyl sulfonyl) aniline
7669-50-2
- US $48.00-40.00 / KG
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
-
- 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
76697-50-2
- US $100.00 / KG
- 98%
- Career Henan Chemical Co
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