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Diphenylethylphosphine oxide

Diphenylethylphosphine oxide Structure
Diphenylethylphosphine oxide structure
CAS No.
1733-57-9
Chemical Name:
Diphenylethylphosphine oxide
Synonyms
ETHYLDIPHENYLPHOSPHINE OXIDE;AURORA KA-1563;ethydiphenylphosphine oxide;diphenylethyl-phosphineoxid;Diphenylethylphosphine oxide;Phosphine oxide, ethyldiphenyl-;Ethyldiphenylphosphine oxide 97%;Diphenylphosphinoethane monoxide;[ethyl(phenyl)phosphoryl]benzene;Diphenylethylphosphine oxide, 98+%
CBNumber:
CB2761547
Molecular Formula:
C14H15OP
Molecular Weight:
230.24
MDL Number:
MFCD00013912
MOL File:
1733-57-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:26
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Diphenylethylphosphine oxide Properties

Melting point 120-125 °C (lit.)
Boiling point 179-180°C 14mm
Density 1,064 g/cm3
Flash point >110°C
storage temp. Store at room temperature
form solid
Appearance White to off-white Solid
InChI 1S/C14H15OP/c1-2-16(15,13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12H,2H2,1H3
InChIKey AKTGKEBIBGSCLD-UHFFFAOYSA-N
SMILES CCP(=O)(c1ccccc1)c2ccccc2
CAS DataBase Reference 1733-57-9(CAS DataBase Reference)
FDA UNII CB83WF95OB
UNSPSC Code 12352002
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
RIDADR  3278
WGK Germany  3
RTECS  SZ0199240
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Diphenylethylphosphine oxide price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 454419 Ethyldiphenylphosphine oxide 97% 1733-57-9 5g $468 2023-06-20 Buy
Activate Scientific AS225996 Diphenylethylphosphine oxide 95% 1733-57-9 1g $109 2026-06-04 Buy
Activate Scientific AS225996 Diphenylethylphosphine oxide 95% 1733-57-9 5g $274 2026-06-04 Buy
aablocks AA001YOM Ethyldiphenylphosphine oxide 98% 1733-57-9 100mg $27 2026-05-28 Buy
aablocks AA001YOM Ethyldiphenylphosphine oxide 98% 1733-57-9 250mg $39 2026-05-28 Buy
Product number Packaging Price Buy
454419 5g $468 Buy
AS225996 1g $109 Buy
AS225996 5g $274 Buy
AA001YOM 100mg $27 Buy
AA001YOM 250mg $39 Buy

Diphenylethylphosphine oxide Chemical Properties,Uses,Production

Uses

Reactant for:

  • Regioselective lactonization of unsymmetrical 1,4-diols
  • Synthesis of a nanostructured dioxomolybdenum(VI) catalyst for liquid-phase epoxidation of olefins
  • Reduction of tertiary phosphine oxides with DIBAL-H
  • Diphenylphosphineyl-mediated synthesis of ketones
  • Nucleophilic aromatic substitution of hydrogen by phosphorous stabilized carbanions
  • Stereospecific reduction to form phosphines

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 3931, 1983 DOI: 10.1016/S0040-4039(00)94318-1

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling

storage

DIPHENYLETHYLPHOSPHINE OXIDE is irritant; moisture sensitive; stored under N2; needs refrigeration

Diphenylethylphosphine oxide synthesis

64-17-5
4559-70-0
1733-57-9
Synthesis of Diphenylethylphosphine oxide from Ethanol and Diphenylphosphine oxide

Diphenylethylphosphine oxide Preparation Products And Raw materials

Raw materials

Phosphine oxide, ethylphenyl- alpha-(Diphenylphosphinyl)-ethanol Ethyltriphenylphosphonium iodide Diphenyl(vinyl)phosphine oxide Diphenyliodonium trifluoromethanesulfonate
Sodium ethoxide Bromoethane Phenylboronic acid Ethanol Ethyl diphenylphosphinite
Diphenylphosphine oxide

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Preparation Products

1-methoxy-4-[methyl(phenyl)phosphoryl]benzene Phosphine oxide, diethylphenyl-

Diphenylethylphosphine oxide Suppliers

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Zhengzhou Kingorgchem Chemical Technology Co., Ltd.gy Co., Ltd. 0371-65511006 18625597674 info@kingorgchem.com;sales@kingorgchem.com China 806 55
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4578 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4372 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Bide Pharmatech Ltd. 60
Shanghai Kewel Chemical Co., Ltd. 50
Sigma-Aldrich 80
Zhengzhou Kingorgchem Chemical Technology Co., Ltd.gy Co., Ltd. 55
Lynnchem 58
Novachemistry 58
Aikon International Limited 58

Diphenylethylphosphine oxide Spectrum

DIPHENYLETHYLPHOSPHINE OXIDE(1733-57-9)MSDIPHENYLETHYLPHOSPHINE OXIDE(1733-57-9)1HNMRDIPHENYLETHYLPHOSPHINE OXIDE(1733-57-9)13CNMRDIPHENYLETHYLPHOSPHINE OXIDE(1733-57-9)IR1

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AURORA KA-1563 [ethyl(phenyl)phosphoryl]benzene Diphenylphosphinoethane monoxide Ethyldiphenylphosphine oxide 97% diphenylethyl-phosphineoxid Phosphine oxide, ethyldiphenyl- Ethyldiphenyl phosphine oxide, 98 % Diphenylethylphosphine oxide, 98+% ethydiphenylphosphine oxide ETHYLDIPHENYLPHOSPHINE OXIDE Diphenylethylphosphine oxide 1733-57-9 C2H5PC6H52O Catalysis and Inorganic Chemistry Phosphorus Compounds Phosphine Ligands Catalysis and Inorganic Chemistry Phosphine Ligands Phosphorus Compounds