1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-
![1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- Structure](CAS/20210111/GIF/856691-44-6.gif)
- CAS No.
- 856691-44-6
- Chemical Name:
- 1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-
- Synonyms
- ONO-9780307;1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-
- CBNumber:
- CB28347178
- Molecular Formula:
- C30H35NO7
- Molecular Weight:
- 521.6
- MDL Number:
- MOL File:
- 856691-44-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- Properties
| Boiling point | 725.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | DMSO : 190 mg/mL (364.26 mM; Need ultrasonic) |
| pka | 4.25±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0066007 | ONO-9780307 99.94% | 856691-44-6 | 5mg | $704 | 2026-06-04 | Buy |
| ChemScene | CS-0066007 | ONO-9780307 99.94% | 856691-44-6 | 10mg | $1062 | 2026-06-04 | Buy |
| ChemScene | CS-0066007 | ONO-9780307 99.94% | 856691-44-6 | 25mg | $1896 | 2026-06-04 | Buy |
| ChemScene | CS-0066007 | ONO-9780307 99.94% | 856691-44-6 | 50mg | $2871 | 2026-06-04 | Buy |
| ChemScene | CS-0066007 | ONO-9780307 99.94% | 856691-44-6 | 100mg | $4333 | 2026-06-04 | Buy |
1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- Chemical Properties, Uses, Production
Uses
ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1].
Biological Activity
ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1]. VT107 (0.1~10000 μM; LPA1-B103 and Vector-B103 cells) results in inhibition of Ca2+ mobilization[1].ONO-9780307 is used to solve the LPA1 crystal structure, binds to an orthosteric site in LPA1[1].
IC 50
LPA1 Receptor: 2.7 nM (IC50)
References
[1]. Mizuno H, et al. Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry. J Lipid Res. 2019;60(1):212-217.
1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Olix ( Hubei) Pharmaceutical Technology Co., Ltd | 17316404525 17316404525 | 209533805@qq.com | China | 9769 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50068 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Nantong QuanYi Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| Olix ( Hubei) Pharmaceutical Technology Co., Ltd | 58 |
| Aladdin Scientific | 58 |
856691-44-6 (1H-Pyrrole-3-acetic acid, 1-[(2S,3S)-2-[(2,3-dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-) Related Search:
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