Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]-
![Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- Structure](CAS/20210111/GIF/133162-24-0.gif)
- CAS No.
- 133162-24-0
- Chemical Name:
- Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]-
- Synonyms
- Aminoarteether;SM934 free base;β-Aminoarteether;β-Aminoarteether, 10 mM in DMSO;Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]-
- CBNumber:
- CB28359317
- Molecular Formula:
- C17H29NO5
- Molecular Weight:
- 327.42
- MDL Number:
- MFCD34470920
- MOL File:
- 133162-24-0.mol
- MSDS File:
- SDS
Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- Properties
| Boiling point | 421.0±45.0 °C(Predicted) |
|---|---|
| Density | 1.20±0.1 g/cm3(Predicted) |
| pka | 8.46±0.10(Predicted) |
| form | Oil |
| color | Light yellow to yellow |
| FDA UNII | 2TF7EGV39I |
Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0140201 | β-Aminoarteether 99.29% | 133162-24-0 | 5mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0140201 | β-Aminoarteether 99.29% | 133162-24-0 | 10mg | $780 | 2026-06-04 | Buy |
| ChemScene | CS-0140201 | β-Aminoarteether 99.29% | 133162-24-0 | 25mg | $1327 | 2026-06-04 | Buy |
| ChemScene | CS-0140201 | β-Aminoarteether 99.29% | 133162-24-0 | 50mg | $1896 | 2026-06-04 | Buy |
| ChemScene | CS-0140201 | β-Aminoarteether 99.29% | 133162-24-0 | 100mg | $2654 | 2026-06-04 | Buy |
Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- Chemical Properties, Uses, Production
Uses
β-Aminoarteether (SM934 free base) is an Artemisinin derivative with orally active. β-Aminoarteether can be used for inflammation and autoimmune disease research, such as lupus diseases[1].
Definition
ChEBI: Beta-aminoarteether is an artemisinin derivative in which the lactone of (+)-artemisinin has been converted into the corresponding lactol 2-aminoethyl ether [beta (S) configuration at the new stereocentre]. It is an artemisinin derivative and a primary amino compound.
in vivo
β-Aminoarteether (SM934; 1-10 mg/kg; oral administration; daliy; for 3 months) treatment significantly delays the progression of glomerulonephritis and increases the survival rate of NZB/W F1 mice. β-Aminoarteether treatment promots the IL-10 production of macrophages from NZB/W F1 mice[1].
| Animal Model: | Female NZB/W F1 mice (Six and half months old)[1] |
| Dosage: | 1 mg/kg, 3 mg/kg, and 10 mg/kg |
| Administration: | Oral administration; daliy; for 3 months |
| Result: | Significantly delayed the progression of glomerulonephritis and increased the survival rate of NZB/W F1 mice. |
References
[1] Li-Fei Hou, et al. SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development. PLoS One. 2012;7(2):e32424. DOI:10.1371/journal.pone.0032424
[2] Yang FM, Fan D, Yang XQ, et al. The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling. Acta Pharmacol Sin. 2021;42(4):593-603. DOI:10.1038/s41401-020-0484-5
Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9185 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| Henan Yinuokai New Materials Co., Ltd | 15565215982 15565215982 | 15565215982@163.com | China | 3768 | 58 |
| Hubei YoungXin Pharmaceutical Tech Co.,Ltd. | 0714-3999001 19171453112 | 2881391661@qq.com | China | 9990 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
View Latest Price from Ethanamine, 2-[[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]oxy]- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-30 | β-Aminoarteether
133162-24-0
|
$148.00-596.00 | 96.09% | 10g | TargetMol Chemicals Inc. |
-
- β-Aminoarteether
133162-24-0
- $148.00-596.00
- 96.09%
- TargetMol Chemicals Inc.
