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L-Homoserine

L-Homoserine structure

CAS No.: 672-15-1

Chemical Name:: L-Homoserine

Synonyms: HOMOSERINE;HSE;(S)-2-AMINO-4-HYDROXYBUTANOIC ACID;H-HOMOSER-OH;H-HSE-OH;H-HOSER-OH;H-HOMOSERINE;(2S)-2-Amino-4-hydroxybutanoic acid;RODH;SDR9C6

CBNumber:: CB2854094

Molecular Formula:: C4H9NO3

Molecular Weight:: 119.12

MDL Number:: MFCD00063090

MOL File:: 672-15-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-22 18:57:36

Product description	Number	Pack Size	Price
L-Homoserine	H6515	1g	$397
L-Homoserine	H6515	5g	$1950
L-(-)-Homoserine for synthesis	8.14359	1g	$161
L-Homoserine >98.0%(T)	H1030	1g	$62
L-Homoserine >98.0%(T)	H1030	5g	$204
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L-Homoserine Properties

Melting point	203 °C (dec.)(lit.)
alpha	-8.5 º (c=2, H2O 22 ºC)
Boiling point	222.38°C (rough estimate)
Density	1.3126 (rough estimate)
refractive index	1.4183 (estimate)
storage temp.	Store below +30°C.
solubility	1100g/l
pka	2.71(at 25℃)
form	Crystalline Powder
color	White to light yellow
optical activity	-8.825 (H2O) +18.326 (2 mol dm-3 HCl)
Water Solubility	1100 g/L (30 ºC)
Merck	14,4739
BRN	1721681
InChI	1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChIKey	UKAUYVFTDYCKQA-VKHMYHEASA-N
SMILES	[N+H3][C@@H](CCO)C(=O)[O-]
LogP	-1.289 (est)
CAS DataBase Reference	672-15-1(CAS DataBase Reference)
FDA UNII	6KA95X0IVO
UNSPSC Code	12352209
NACRES	NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P271-P280

Risk Statements

36/37/38

Safety Statements

24/25-44-35-26-28-7-4-3/9

WGK Germany

HS Code

29225000

Storage Class

11 - Combustible Solids

NFPA 704

	0
0		0

L-Homoserine price More Price(68)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H6515	L-Homoserine	672-15-1	1g	$397	2026-04-30	Buy
Sigma-Aldrich	H6515	L-Homoserine	672-15-1	5g	$1950	2026-04-30	Buy
Sigma-Aldrich	8.14359	L-(-)-Homoserine for synthesis	672-15-1	1g	$161	2026-04-30	Buy
TCI Chemical	H1030	L-Homoserine >98.0%(T)	672-15-1	1g	$62	2026-04-30	Buy
TCI Chemical	H1030	L-Homoserine >98.0%(T)	672-15-1	5g	$204	2026-04-30	Buy

Product number	Packaging	Price	Buy
H6515	1g	$397	Buy
H6515	5g	$1950	Buy
8.14359	1g	$161	Buy
H1030	1g	$62	Buy
H1030	5g	$204	Buy

L-Homoserine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystalline powder

Uses

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.

Definition

ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 3147, 1958 DOI: 10.1021/ja01545a057
The Journal of Organic Chemistry, 24, p. 1794, 1959 DOI: 10.1021/jo01093a610

General Description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Biochem/physiol Actions

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

Purification Methods

Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]

L-Homoserine synthesis

Synthesis of L-Homoserine from L-METHIONINE METHYLSULFONIUM IODIDE

L-Homoserine Preparation Products And Raw materials

Raw materials

Preparation Products

DL-Threonine L-Lysine hydrochloride N-Fmoc-L-homoserine O-ACETYL-L-HOMOSERINE HYDROCHLORIDE

L-Homoserine Suppliers

Global( 541)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21588	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
AB PharmaTech,LLC	323-480-4688	sales@acrospharmatech.com	United States	989	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29817	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1319	58

Supplier	Advantage
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Shanghai Yingrui Biopharma Co.,Ltd	58

View Lastest Price from L-Homoserine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-15	L-Homoserine 672-15-1	US $0.00 / KG	1KG	98.0%	5000kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-15	L-Homoserine 672-15-1	US $2.00 / box	1box	99.99%	200000T	Anhuyan (Hainan) Biotechnology Co., LTD
2026-04-22	L-Homoserine 672-15-1	US $0.00 / removed		99.77%	10g	TargetMol Chemicals Inc.

L-Homoserine
672-15-1
US $0.00 / KG
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

L-Homoserine
672-15-1
US $2.00 / box
99.99%
Anhuyan (Hainan) Biotechnology Co., LTD

L-Homoserine
672-15-1
US $0.00 / removed
99.77%
TargetMol Chemicals Inc.

L-Homoserine Spectrum

L-Homoserine(672-15-1)MS L-Homoserine(672-15-1)¹HNMR L-Homoserine(672-15-1)¹³CNMR L-Homoserine(672-15-1)IR1 L-Homoserine(672-15-1)IR2 L-Homoserine(672-15-1)Raman

672-15-1(L-Homoserine)Related Search:

trans-4-Hydroxy-L-proline methyl ester hydrochloride beta-Methyl L-aspartate hydrochloride H-ASP(OTBU)-OTBU HCL Dimethyl L-aspartate hydrochloride H-CIS-HYP-OME HCL

H-ASP(OET)-OET HCL L-Threonine DL-4-Amino-3-hydroxybutyric acid L(+)-allo-Threonine allo-DL-Threonine

DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE 2-Hydroxy-4-amino butanoic acid (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid DL-Homoserine (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID

D(-)-allo-Threonine H-ASP-OBZL HCL H-ASP(OTBU)-OME HCL

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(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID (S)-2-AMINO-4-HYDROXYBUTYRIC ACID L-2-AMINO-4-HYDROXYBUTANOIC ACID L-2-AMINO-4-HYDROXYBUTYRIC ACID L-2-AMINO-4-HYDROXYBUTYRIC ACID HYDROCHLORIDE H-L-HSE-OH H-HSE-OH H-HOSER-OH H-HOSER-OH HCL H-HOMOSER-OH H-HOMOSERINE HSE HOMOSERINE HOMOSERINE-L 2-AMINO-4-HYDROXYBUTYRIC ACID L-2-Amino-4-hydroxybutyricacid=H-Hser-OH (S)-2-AMINO-4-HYDROXYBUTANOIC ACID (S)-Homeserine HOMOSERINE, (S)-2-AMINO-4-HYDROXYBUTYRIC ACID L-Homoserine, (S)-2-Amino-4-hydroxybutyric acid H-HOSER-OHCL L-Beta-Homo-Ser (2S)-2-Amino-4-hydroxybutanoic acid H-HoSer-OHCl;H-HoSer-OHCl L-Homoserine,97% (S)-2-Amino-4-hydroxybutyric acid Hse L-Homoserine 98% (S)-2-Amino-4-hydroxybutyric acid Hse H-HoSer-OH H-Hser-OH ,98% L-Homoserine NSC 206251 L-(-)-HOMOSERINE FOR SYNTHESIS L-HoMoserine, 95+% HSD17B6 RODH SDR9C6 L-Homoserine, >=98% L-Homoserine> L-Homoserine USP/EP/BP laevo-homoserine (2S)-2-azaniumyl-4-hydroxybutanoate L-Homoserine 672-15-1 L-Homoserine (9CI, ACI) (2S)-2-amino-4-hydroxybutanoic acid (homoserine) Lysine Impurity 12 (L-?Homoserine) LChemicalbook-2-AMINO-4-HYDROXYBUTYRICACID Carisoprodol Impurity 3 (Carisoprodol EP Impurity C) L-Homoserine, 10 mM in DMSO L-Homoserine H-HSer-OH, H-Hse-OH, H-HoSer-OH 672-15-1 6-00-6 627-15-1 HOCH2CH2CHNH2COOH Amino Acid Library BioChemical Homo-Amino Acids Metabolomics